Welcome
Thank you for visiting the Transgenic Mouse Model core website at Oregon Health and Science University. The core is located in the Biomedical Research Building in order to take advantage of the new pathogen-free barrier animal facility. Currently, the TMM Core is generating CRISPR/cas9 knock-out and knock-in, conventional knock-out, and transgenic mice, as well as performing various other services (cryopreserving mouse embryos and sperm, carrying out IVF) for the researchers of OHSU and other organizations.
Changes to the Transgenic Mouse Models Core
We want to acknowledge the valuable contributions of Lev Fedorov, Ph.D., who will retire at the end of December 2024, to the Transgenic Mouse Models (TMM) core and OHSU research community. During his 16-plus years of service, Fedorov’s leadership enabled the TMM Core to support numerous projects and advance our capabilities in transgenic mouse models and their contributions to research.
The TMM core will transition to a new, reduced-service operating model which continue to offer some essential services, including cryopreservation of mouse embryos and sperm, long-term storage in dedicated cryo-freezers and rederivation of mouse strains to specific pathogen-free status by embryo transfer. Generation of genetically modified mouse strains will no longer be offered.
