RPR with Reflex to Titer for Treatment Response or Reinfections
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
Routine: 5 to 24 Hours
Urgent: 5 to 24 Hours
Test Schedule:
7 days a week
Specimen Requirements:
6.0 mL blood in serum separator tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. A minimum of 1 mL serum is needed.
Storage/Transport Temperature: Refrigerated 5 days; Frozen if delayed in testing (avoid repeated freeze/thaw cycles).
Unacceptable Specimens: grossly hemolyzed, grossly lipemic, contaminated, plasma, CSF or other body fluids.
Pediatric Specimen Requirements:
1.0 mL blood in serum separator tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. A minimum of 1 mL serum is needed.
Storage/Transport Temperature: Refrigerated 5 days; Frozen if delayed in testing (avoid repeated freeze/thaw cycles).
Unacceptable Specimens: grossly hemolyzed, grossly lipemic, contaminated, plasma, CSF or other body fluids.
Reference Range:
RPR: Nonreactive
RPR Titer: Less than 1:1
Comments:
Preferred test for monitoring treatment response in established syphilis.
Methodology: Semi-Quantitative Particle Agglutination
If RPR is reactive, then a RPR titer will be added. Additional charges will apply.
Hepatitis B Surface AG W/Reflex Confirmation
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
2 Days
Test Schedule:
Monday through Friday.
Specimen Requirements:
4 mL blood in GOLD serum separator tube or a RED top tube.
Pediatric Specimen Requirements:
2 mL blood in GOLD serum separator tube or a RED top tube.
Synonyms:
HBS
HBSAG
Hep B Surf AG
Hep B Surf AG Confirmation
Syphilis Antibody Screen W/ Reflex To RPR, Titer, and TP-PA Confirm
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
Routine: 5 to 24 Hours
Urgent: 5 to 24 Hours
Test Schedule:
7 days a week
Interpretation:
| Result | Final Interpretation |
| Non - Reactive | Non-reactive for treponema antibodies |
| Reactive | Reactive for treponema antibodies |
Specimen Requirements:
6.0 mL blood in serum separator tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. A minimum of 2 mL serum is needed. Avoid freezing.
Storage/Transport Temperature: Refrigerated. Avoid freezing.
Unacceptable Specimens: grossly hemolyzed, grossly lipemic, contaminated, plasma, CSF or other body fluids.
Pediatric Specimen Requirements:
1.0 mL blood in serum separator tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. A minimum of 2 mL serum is needed.
Storage/Transport Temperature: Refrigerated. Avoid freezing.
Unacceptable Specimens: grossly hemolyzed, grossly lipemic, contaminated, plasma, CSF or other body fluids.
Reference Range:
Treponema pallidum Antibodies: Nonreactive
RPR: Nonreactive
RPR Titer: Less than 1:1
Comments:
Recommended test for syphilis screen for patients 18 months old or older (reverse algorithm).
Methodology: Chemiluminescent microparticle immunoassay (CMIA) technology
If Treponema antibodies screen is reactive, then a RPR with Reflex to RPR Titer or T. pallidum Antibody by Particle Agglutination [LAB103951] will be added. T. pallidum Antibody by Particle Agglutination (Opens in a new window) is performed by ARUP.
Additional charges will apply.
Immunoglobulin Panel
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Includes:
IgA, Serum
IgG, Serum
IgM, Serum
Turnaround Time:
Routine: 4 days
Test Schedule:
Monday, Wednesday, and Friday.
Specimen Requirements:
2 mL blood in a GOLD top tube. Separate serum from cells ASAP or within 2 hours of collection. Send 1 mL aliquot refrigerated.
Stability:
Plasma is stable for 7 days refrigerated at 2-8 C
Pediatric Specimen Requirements:
Minimum volume = 0.5mL serum
Reference Range:
IgG 768 - 1632 (mg/dL)
IgA 68 - 408 (mg/dL)
IgM 35 – 263 (mg/dL)
Synonyms:
IgA
IgG
IgM
HIV AB/AG Screening w/Reflex to Quant
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Includes:
HIV AB/AG Screen
If Screen is Reactive, reflex to:
HIV-1 RNA Quant (LAB00779)
HIV Ab Confirmation
Turnaround Time:
Routine: 2 days, additional time for reflex testing.
Test Schedule:
HIV AB/AG Screen = 7 days a week
HIV RNA Quant = Tuesday and Friday
HIV AB Confirm = 7 days a week
Specimen Requirements:
6 mL LAVENDER top (EDTA) vacutainer. Purple top only for reflex to viral load testing.
Send 1 mL aliquot of plasma refrigerated, do not aliquot all plasma off the cells. Send plasma and cells.
Stability:
Whole blood collected in EDTA tubes may be stored and/or transported for up to 24 hours at room temp or refrigerated (2 to 25 C) prior to plasma separation
Refrigerated (2 to 8 C) plasma is stable for up to 7 days for HIV AB/AG Screen and HIV AB Confirm, 6 days for HIV RNA QUANT
Pediatric Specimen Requirements:
Do not order for pediatric patients less than 2 years of age, see Comment section below.
Minimum volume for testing = 1 mL plasma, do not aliquot all plasma off the cells. Send plasma and cells.
Stability:
Reference Range:
Nonreactive
Comments:
Billable EAP and CPT Codes: Reflexes create additional charges.
Do not order for pediatric patients less than 2 years of age. NIH guidelines recommend virologic assays (i.e. RNA tests) that directly detect HIV for diagnosis of HIV infection in infants younger than 2 years.
This test is not intended for use in screening blood, plasma or tissue donors.
Synonyms:
AIDS Antibody Screen
Acquired Immunodeficiency Syndrome
HIV Antibody Screen
HIV - 1,2 AB/ HIV-1 P24 AG Screen
HIV P-24 Antigen
Human Immunodeficiency Virus
P-24 Antigen
Monoclonal Protein Study – SPEP and Immunotyping
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
Routine: 7 days
Test Schedule:
Monday through Friday.
Specimen Requirements:
4 mL blood in a GOLD top tube. Separate serum from cells ASAP or within 2 hours of collection. A minimum of 2.0 mL serum is needed.
Synonyms:
IFE
Immunoelectrophoresis
Immunofixation
Monoclonal Protein Detection Quantitation and Characterization
MGUS study
Monoclonal Protein Study
Multiple Myeloma Study
Protein ELP
Protein Electrophoresis
Serum Protein Electrophoresis
SPEP
Monoclonal Protein Study Expanded Panel, Serum
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
Routine: 6 days
Test Schedule:
SPEP reflex to Immunotyping: Monday through Friday.
Immunoglobulin Panel: Monday, Wednesday, and Friday.
Specimen Requirements:
Labels for two specimens will print.
SPEP reflex to Immunotyping: 4 mL blood in a GOLD top tube. Separate serum from cells ASAP or within 2 hours of collection. A minimum of 2.0 mL serum is needed.
Immunoglobulin Panel Serum: 2 mL blood in a GOLD top tube. Separate serum from cells ASAP or within 2 hours of collection. A minimum of 1.0 mL serum is needed.
Tacrolimus
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
Routine: 1 day
Test Schedule:
Monday through Friday.
Units:
Critical Values:
20 ng/mL or greater.
Specimen Requirements:
3 mL blood in a LAVENDER top tube (EDTA); redraw if specimen clotted. Specimen is stable for up to 7 days refrigerated (2 to 8 C). If testing is delayed more than 7 days, store frozen at -10 C or less.
Pediatric Specimen Requirements:
0.5 mL blood in a LAVENDER top tube (EDTA); redraw if specimen clotted. Specimen is stable for up to 7 days refrigerated (2 to 8 C). If testing is delayed more than 7 days, store frozen at -10 C or less.
Reference Range:
Therapeutic range: 5 to 15 ng/mL
Comments:
Test performed by immunoassay using Abbott Architect i2000.
Samples for analysis of Tacrolimus should be collected 30 minutes to 1 hour prior to the next dose so that the measured concentration of drug represents trough level. Some other factors influencing therapeutic range, dose administered, and result interpretation include time since transplantation, the organ transplanted, co-administration of other immunosuppressants and interaction with other drugs that may increase or decrease Tacrolimus concentrations.
Synonyms:
FK506 (Tacrolimus), Whole Blood
Sirolimus Quantitation
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
Routine: 1 day
Test Schedule:
Monday through Friday.
Units:
Specimen Requirements:
3 mL blood in a LAVENDER top tube (EDTA); redraw if specimen clotted. Specimen is stable for up to 7 days refrigerated (2 to 8 C). If testing is delayed more than 7 days, store frozen at -10 C or less.
Pediatric Specimen Requirements:
0.5 mL blood in a LAVENDER top tube (EDTA); redraw if specimen clotted. Specimen is stable for up to 7 days refrigerated (2 to 8 C). If testing is delayed more than 7 days, store frozen at -10 C or less.
Reference Range:
4 to 12 ng/mL
Comments:
Test performed by immunoassay using Abbott Architect i2000.
Kidney transplant (in combination with Cyclosporine): 4 to 12 ng/mL
Toxic value: greater than 25 ng/mL
Interpretive Data: A range of 12 to 20 ng/mL has been suggested for liver transplant. Samples for analysis of Sirolimus should be collected 30 minutes to 1 hour prior to the next dose so that the measured concentration of drug represents trough levels. The optimal therapeutic range for a given patient may differ from this suggested range based on the indication for therapy, treatment phase (initiation or maintenance), use in combination with other drugs, time of specimen collection relative to prior dose and/or type of transplanted organ.
Synonyms:
Rapamune
Rapamycin
RPR With Reflex to Titer and TP-PA Confirmation
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
Routine: 5 to 24 Hours
Urgent: 5 to 24 Hours
Test Schedule:
7 days a week
Specimen Requirements:
6.0 mL blood in serum separator tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. A minimum of 1 mL serum is needed.
Storage/Transport Temperature: Refrigerated 5 days; Frozen if delayed in testing (avoid repeated freeze/thaw cycles).
Unacceptable Specimens: grossly hemolyzed, grossly lipemic, contaminated, plasma, CSF or other body fluids.
Pediatric Specimen Requirements:
1.0 mL blood in serum separator tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. A minimum of 1 mL serum is needed.
Storage/Transport Temperature: Refrigerated 5 days; Frozen if delayed in testing (avoid repeated freeze/thaw cycles).
Unacceptable Specimens: grossly hemolyzed, grossly lipemic, contaminated, plasma, CSF or other body fluids.
Reference Range:
RPR: Nonreactive
RPR Titer: Less than 1:1
Comments:
Recommended test for congenital syphilis screen for patients less than 18 months old (traditional algorithm).
Methodology: Semi-Quantitative Particle Agglutination
If RPR is reactive, then a RPR titer and TP-PA confirmation will be added. Additional charges apply. TP-PA is sent to ARUP for confirmation Treponema pallidum Antibody by TP-PA (Opens in a new window).
Synonyms:
Syphilis Serology
Syphilis Reverse Testing Algorithm
Rapid Plasma Reagin
Rapid Plasma Reagin Reflex to Titer or TPPA