Antibody Identification

Orderable EAP code:

LAB00223

Billable EAP Codes:

80001619 x 1

CPT Codes:

86870 x 1

Lab Section:

Transfusion Services

Turnaround Time:

Routine: 8 hours
Urgent: 2 hours

Test Schedule:

Available 24 hours a day.

Interpretation:

Interpretive report provided. 

Specimen Requirements:

6.0 mL blood LAVENDER top tube. Specimen stability: up to 3 days at room temperature.
See link for instructions for identification and labeling of Transfusion Service specimens. 
Sample Information (Opens in a new window)

Pediatric Specimen Requirements:

Less than 4 months old:  2 mL blood in a LAVENDER top tube.
4 months to 3 years: 3 mL blood in a LAVENDER top tube.
Specimen stability: up to 3 days at room temperature.

Reference Range:

Reflexed whenever antibody screen is positive.

Comments:

Serum red blood cell antibody specificity is determined by reacting patient serum with extended panel of reagent red blood cells of known phenotype. The clinical significance of some of the more commonly encountered red cell alloantibodies are summarized in the Transfusion Manual. Clinically significant alloantibodies (e.g., Rh, Kell, Duffy, Kidd) may be present in patients with hemolytic transfusion reactions or hemolytic disease of the newborn. Serum autoantibodies usually react with all panel cells (i.e. "panagglutinins"), and are present in the sera of 80% of patients with warm (IgG) autoimmune hemolytic anemia.

Synonyms:

Panel Study
Red Cell Antibody Identification
Red Cell Panel

Pre-BMT Type and Screen

Orderable EAP code:

LAB100508

Billable EAP Codes:

80001606 x 1
80001618 x 1
80001648 x 1

CPT Codes:

86901 x 1
86850 x 1
86900 x 1

Lab Section:

Transfusion Services

Turnaround Time:

Routine: 2 hours
Urgent: 1 hour

Test Schedule:

Available 24 hours a day.

Specimen Requirements:

6.0 mL blood in a LAVENDER top tube. Specimen stability: up to 3 days at room temperature.
See link for instructions for identification and labeling of Transfusion Service specimens. 
Sample Information. (Opens in a new window)

Pediatric Specimen Requirements:

Less than 4 months old: 1 to 2 mL blood in a LAVENDER top tube. 
4 months to 3 years: 3 mL blood in a LAVENDER top tube.
Specimen stability: up to 3 days at room temperature.

Reference Range:

If the antibody screen is positive, antibody identification will automatically be performed.

Comments:

Should be ordered prior to a patient receiving a bone marrow transplant. When this specimen is drawn or as soon as the information is available, a BMT Transfusion Profile should also be ordered in EPIC. The BMT Transfusion Profile gives Nursing and the Transfusion Service details about the transplant, including the donor ABO/Rh type and what blood products (plasma products and red cell containing products) the patient should receive during and after they have received their transplant.

Transfusion Reaction Workup

Orderable EAP code:

LAB100052

Billable EAP Codes:

80001648 x 1
80001606 x 1
80001622 x 1

CPT Codes:

86900 x 1
86901 x 1
86880 x 1

Lab Section:

Transfusion Services

Turnaround Time:

Routine: N/A
Urgent: 1 hour

Test Schedule:

Available 24 hours a day.

Specimen Requirements:

6.0 mL blood in a LAVENDER top tube. Specimen stability: up to 24 hours at room temperature.
See link for instructions for identification and labeling of Transfusion Service specimens. 
Sample Information. (Opens in a new window)

Pediatric Specimen Requirements:

Less than 4 months old: 1 to 2 mL blood in a LAVENDER top tube.
4 months to 3 years: 3 mL blood in a LAVENDER top tube.
Specimen stability: up to 24 hours at room temperature.

Comments:

Following a suspected transfusion reaction, order a Transfusion Reaction workup, collect the post reaction sample, complete the form reporting the systems. If documenting the administration in EPIC, send the specimen and paperwork with the blood unit and all attached tubing and fluids to Transfusion Service.

NOTE: No additional blood products should be administered until the investigation is complete except for mild itching or hives controlled by antihistamine treatment.    
 

Prenatal Type and Screen

Orderable EAP code:

LAB01083

Billable EAP Codes:

80001648 x 1
80001606 x 1
80001618 x 1

CPT Codes:

86900 x 1
86901 x 1
86850 x 1

Lab Section:

Transfusion Services

Includes:

ABO, Rh, Antibody Screen

Turnaround Time:

Routine: 2 hours
Urgent: 1 hour

Test Schedule:

Available 24 hours a day.

Specimen Requirements:

6.0 mL blood in a LAVENDER top tube. Specimen stability: up to 3 days at room temperature.
See link for instructions for identification and labeling of Transfusion Service specimens. 
Sample Information (Opens in a new window)

Pediatric Specimen Requirements:

Less than 4 months old: 1 to 2 mL in a LAVENDER top tube.
4 months to 3 years: 2.0 mL in a LAVENDER top tube.
Specimen stability: up to 3 days at room temperature.

Comments:

To be used for prenatal patients only. If the antibody screen is positive and an antibody implicated in causing Hemolytic Disease of the Newborn (HDN) is identified, antibody titers will be reflexed.

Prenatal Antibody Screen

Orderable EAP code:

LAB01082

Billable EAP Codes:

80001618 x 1

CPT Codes:

86850 x 1

Lab Section:

Transfusion Services

Turnaround Time:

Routine: 2 hours
Urgent: 1 hour

Test Schedule:

Available 24 hours a day.

Specimen Requirements:

6.0 mL blood in a LAVENDER top tube. Specimen stability: up to 3 days at room temperature.
See link for instructions for identification and labeling of Transfusion Service specimens. 
Sample Information (Opens in a new window)

Pediatric Specimen Requirements:

Less than 4 months old: 1 to 2 mL in a LAVENDER top tube.
4 months to 3 years: 2.0 mL in a LAVENDER top tube.
Specimen stability: up to 3 days at room temperature.

Comments:

To be used for prenatal patients only, when ABO/Rh is not required, and only antibody screen is requested. If the antibody screen is positive, and an antibody implicated in causing Hemolytic Disease of the Newborn (HDN) is identified, antibody titers will be reflexed.

Cord Blood DAT

Orderable EAP code:

LAB102360

Billable EAP Codes:

80001622 x 1

CPT Codes:

86880 x 1

Lab Section:

Transfusion Services

Turnaround Time:

Routine: 2 hours
Urgent: 1 hour

Test Schedule:

Available 24 hours a day.

Specimen Requirements:

1.0 mL blood in a LAVENDER top tube. Specimen stability: up to 3 days at room temperature.
See link for instructions for identification and labeling of Transfusion Service specimens. 
Sample Information (Opens in a new window)

Pediatric Specimen Requirements:

1.0 mL blood in a LAVENDER top tube. Specimen stability: up to 3 days at room temperature.

Reference Range:

Negative

Comments:

Demonstrates the presence of immunoglobulins, complement, or protein adsorbed to red cells of a neonate or infant. Of value in the diagnosis and evaluation of hemolytic anemia, hemolytic disease of the newborn, suspected transfusion reactions, and in some diseases.
Detects the presence of red blood cell-bound IgG and/or complement by agglutination using an antiglobulin (Coombs) reagent. Positive results occurring in cord blood are primarily due to maternal antibodies binding to the infant RBCs and can cause hemolytic disease of the newborn. Extended evaluation may include elution studies.

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