MMG encompasses numerous research faculty, clinicians, fellows, and students with diverse research interests surrounding molecular and medical genetics approaches to understanding the basis and treatment of human disease. Our research includes cancer genetics, molecular genetics, gene therapy technologies, molecular diagnostics, developmental genetics, medical genetics cytogenetics, quantitative trait genetics, biochemical genetics, cell biology and biochemistry. Several laboratories focus on "tumor suppressor" and "oncogene" pathways involved in a variety of common human cancers, with one goal being to capitalize on this knowledge for translational research purposes. One central theme in the program is the utilization of a variety of genetic, molecular and cellular approaches for analyzing normal and disease processes.
Donations can also be made by check; please make check(s) payable to: OHSU Foundation
Account 25260 Genetics Research
OHSU Foundation
P.O. Box 29017
Portland, OR 97296
(800) 462-6608
MMG Highlights
Congratulations to Lucia Carbone and team
They have a fascinating article titled "The complete sequence and comparative analysis of ape sex chromosomes" that was published on May 29, 2024 in Journal Nature.
Congratulations to Hiroyuki Nakai and Team
They have a fantastic article titled "Finding DNA Tags in AAV Stacks" that was published on March 7, 2024 in TheScientist. In this article gives a more in depth look of the work that the Nakai lab does.
Congratulations to Melanie Gillingham and co-authors
Melanie Gillingham, Ph.D., R.D., L.D., has won the 2023 Emmanuel Shapira Award from the Society for Inherited Metabolic Disorders (SIMD). The Shapira Award was established in 2003 to recognize the best paper in the field of biochemical genetics and metabolism published in Molecular Genetics and Metabolism (MGM) by an SIMD member or their trainee.
Dr. Gillingham and her co-authors' paper, titled " Resting and total energy expenditure of patients with long-chain fatty acid oxidation disorders (LC-FAODs),” in MGM Vol. 138, Issue 3, was selected for the award.
Congratulations to Brian O'Roak
Congratulations to Brian O'Roak for being awarded the OBI Neuroscience Campaign Fund's Brain Health Across the Lifespan grant for his project, "An innovative tool for the study of TBR1-related autism," made possible through the OHSU Foundation.
Congratulations to Susan J. Hayflick
Susan J. Hayflick, M.D., Ph.D., professor and chair, molecular and medical genetics, professor, pediatrics and neurology, has been awarded the 2024 Sidney Carter Award in Child Neurology by the American Academy of Neurology (AAN).
The Carter Award, one of the AAN’s premier honors, recognizes outstanding work by an individual in the field of child neurology/developmental neurobiology. Dr. Hayflick was chosen because of her work advancing the study of rare diseases in children. She will be presented this award as part of the AAN’s Presidential Plenary Session on Sunday, April 14, 2024 at the Colorado Convention Center in Denver, CO. where she will deliver the annual Carter Lecture. The title of her talk is “PKAN and the arc of a career.”
OHSU Changemakers
MMG faculty Susan Hayflick, Penny Hogarth, Allison Gregory, Brian O’Roak, and Cary Harding are among the OHSU researchers studying rare diseases. Their work has led to breakthrough discoveries, offering new hope to patients and their families. Read full article.
Meet the author: Andrew Adey
In this interview with Cell Reports Methods, Dr. Andrew Adey talks about developing a more broadly accessible method for paired whole-genome and chromatin accessibility sequencing from single cells, as well as the current and future landscape of genome-scale molecular profiling.