Martin Pike, Ph.D., focuses his research on the pathophysiology of brain diseases, including malignant glioma and stroke, using MRI/MRS in tandem with other approaches. His lab employs dynamic contrast MRI approaches to investigate anti-angiogenic/anti-tumor treatment strategies employing mouse models of malignant glioma. Dr. Pike’s team is currently developing novel combinational treatment strategies for malignant glioma which exploit autophagic cell death. These are implemented in combination with immunohistological analyses and in vitro assessments of underlying mechanisms.

Dr. Pike's goal is to develop effective molecularly targeted combination treatment strategies that will provide hope for patients with malignant glioma. His group is also investigating stroke neuroprotection strategies and using MR based molecular imaging approaches to investigate stroke related inflammation.

Dr. Pike completed his bachelor’s from Williams College in Williamstown, Massachusetts in 1978 and his doctorate in chemistry from the State University of New York in 1985. He was an NIH Postdoctoral Fellow at The Johns Hopkins University School of Medicine, Division of Cardiology in Baltimore, Maryland and, from 1988 to 2008, was a faculty member at the Department of Medicine, division of cardiovascular disease and the Department of Cell Biology at the University of Alabama at Birmingham. He joined OHSU as a visiting scholar at the Advanced Imaging Research Center in 2007 and became a research associate professor at the OHSU Knight Cancer Institute in 2008.