The Zeiss Elyra PS.1 is a combination setup for the following imaging modalities - 

• Laser-scanning confocal microscopy (LSM710). Pinhole-based out-of-focus light rejection in confocal microscopy has long been used for high-resolution imaging. On our setup, this well-accepted methodology can be compared to the more advanced super-resolution technologies without moving the sample.
• Airyscan detection is a super-resolution technology with optical sectioning capabilities that yields up to 5-fold improvement in voxel resolution.
• Super-resolution structured illumination microscopy or SIM. SIM is an easily accessible super-resolution technology that uses standard fluorophores and yields up to 8-fold improvement in voxel resolution.

• Single-molecule localization microscopy, such as PALM and  STORM. Single molecule localization techniques generally require use of unusual labeling techniques, but can yield more than ten-fold lateral resolution improvement. Note that imaging is limited to area close to the coverslip.

Please contact core staff  for a free consultation about your super-resolution imaging needs.