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1. Srivastava, D.K., Navratna, V., Tosh, D.K. et al. Structure of the human dopamine transporter and mechanisms of inhibition. Nature 632, 672–677 (2024).
2. Pezacki, A. T. et al. A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools. Proceedings of the National Academy of Sciences 121, e2401579121 (2024).
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16. Salcedo-Sora, J.E., Robison, A.T.R., Zaengle-Barone, J., Franz, K.J., Kell, D.B., (2021) Membrane Transporters Involved in the Antimicrobial Activities of Pyrithione in Escherichia coli. Molecules 26, 582
17. Smith, A. D., Garcia-Santamarina, S., Ralle, M., Loiselle, D. R., Haystead, T. A., and Thiele, D. J. (2021) Transcription factor-driven alternative localization of Cryptococcus neoformans superoxide dismutase. J Biol Chem, 100391
18. Paul, J. S., and Small, B. C. (2021) Chronic exposure to environmental cadmium affects growth and survival, cellular stress, and glucose metabolism in juvenile channel catfish (Ictalurus punctatus). Aquat Toxicol 230, 105705
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20. Roy, S., McCann, C. J., Ralle, M., Ray, K., Ray, J., Lutsenko, S., and Jayakanthan, S. (2020) Analysis of Wilson disease mutations revealed that interactions between different ATP7B mutants modify their properties. Scientific Reports 10, 13487
21. Morrell, A., Tripet, B. P., Eilers, B. J., Tegman, M., Thompson, D., Copié, V., and Burkhead, J. L. (2020) Copper modulates sex-specific fructose hepatoxicity in nonalcoholic fatty liver disease (NALFD) Wistar rat models. The Journal of nutritional biochemistry 78, 108316
22. Miesen, T. J., Engstrom, A. M., Frost, D. C., Ajjarapu, R., Ajjarapu, R., Lira, C. N., and Mackiewicz, M. R. (2020) A hybrid lipid membrane coating “shape-locks” silver nanoparticles to prevent surface oxidation and silver ion dissolution. RSC Advances 10, 15677-15693
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24. Harris, C. J., Gray, N. E., Caruso, M., Hunter, M., Ralle, M., and Quinn, J. F. (2020) Copper Modulation and Memory Impairment due to Hippocampal Tau Pathology. Journal of Alzheimer's Disease Preprint, 1-12
25. Gudekar, N., Shanbhag, V., Wang, Y., Ralle, M., Weisman, G. A., and Petris, M. J. (2020) Metallothioneins regulate ATP7A trafficking and control cell viability during copper deficiency and excess. Scientific Reports 10, 7856
26. Edwards, S., Zhao, G., Tran, J., Patten, K. T., Valenzuela, A., Wallis, C., Bein, K. J., Wexler, A. S., Lein, P. J., and Rao, X. (2020) Pathological Cardiopulmonary Evaluation of Rats Chronically Exposed to Traffic-Related Air Pollution. Environ Health Perspect 128, 127003
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28. Yang, H., Liu, C.-N., Wolf, R. M., Ralle, M., Dev, S., Pierson, H., Askin, F., Steele, K. E., Magnuson, T. H., Schweitzer, M. A., Wong, G. W., and Lutsenko, S. (2019) Obesity is associated with copper elevation in serum and tissues. Metallomics : integrated biometal science 11, 1363-1371
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31. Jeong, S. Y., Hogarth, P., Placzek, A., Gregory, A. M., Fox, R., Zhen, D., Hamada, J., van der Zwaag, M., Lambrechts, R., Jin, H., Nilsen, A., Cobb, J., Pham, T., Gray, N., Ralle, M., Duffy, M., Schwanemann, L., Rai, P., Freed, A., Wakeman, K., Woltjer, R. L., Sibon, O. C., and Hayflick, S. J. (2019) 4'-Phosphopantetheine corrects CoA, iron, and dopamine metabolic defects in mammalian models of PKAN. EMBO Mol Med 11, e10489
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34. Yadav, R., and Scott, E. E. (2018) Endogenous insertion of non-native metalloporphyrins into human membrane cytochrome P450 enzymes. The Journal of biological chemistry 293, 16623-16634
35. Toro, T. B., Edenfield, S. A., Hylton, B. J., and Watt, T. J. (2018) Chelatable trace zinc causes low, irreproducible KDAC8 activity. Analytical biochemistry 540-541, 9-14
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37. Meacham, K. A., Cortés, M. P., Wiggins, E. M., Maass, A., Latorre, M., Ralle, M., and Burkhead, J. L. (2018) Altered zinc balance in the Atp7b(-/-) mouse reveals a mechanism of copper toxicity in Wilson disease. Metallomics : integrated biometal science 10, 1595-1606
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40. Rupp, J. C., Locatelli, M., Grieser, A., Ramos, A., Campbell, P. J., Yi, H., Steel, J., Burkhead, J. L., and Bortz, E. (2017) Host Cell Copper Transporters CTR1 and ATP7A are important for Influenza A virus replication. Virology journal 14, 11-11
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42. Krey, J. F., Drummond, M., Foster, S., Porsov, E., Vijayakumar, S., Choi, D., Friderici, K., Jones, S. M., Nuttall, A. L., and Barr-Gillespie, P. G. (2016) Annexin A5 is the Most Abundant Membrane-Associated Protein in Stereocilia but is Dispensable for Hair-Bundle Development and Function. Scientific reports 6, 27221-27221
43. Chu, Y. H., Sibrian-Vazquez, M., Escobedo, J. O., Phillips, A. R., Dickey, D. T., Wang, Q., Ralle, M., Steyger, P. S., and Strongin, R. M. (2016) Systemic Delivery and Biodistribution of Cisplatin in Vivo. Mol Pharm 13, 2677-2682
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46. Oh, K. Y., Roberts, V. H. J., Schabel, M. C., Grove, K. L., Woods, M., and Frias, A. E. (2015) Gadolinium Chelate Contrast Material in Pregnancy: Fetal Biodistribution in the Nonhuman Primate. Radiology 276, 110-118
47. Bonnemaison, M. L., Back, N., Duffy, M. E., Ralle, M., Mains, R. E., and Eipper, B. A. (2015) Adaptor Protein-1 Complex Affects the Endocytic Trafficking and Function of Peptidylglycine alpha-Amidating Monooxygenase, a Luminal Cuproenzyme. J Biol Chem 290, 21264-21279
48. Voss, K., Harris, C., Ralle, M., Duffy, M., Murchison, C., and Quinn, J. F. (2014) Modulation of tau phosphorylation by environmental copper. Translational neurodegeneration 3, 24
49. Gaier, E. D., Kleppinger, A., Ralle, M., Covault, J., Mains, R. E., Kenny, A. M., and Eipper, B. A. (2014) Genetic determinants of amidating enzyme activity and its relationship with metal cofactors in human serum. BMC endocrine disorders 14, 58
50. Gaier, E. D., Miller, M. B., Ralle, M., Aryal, D., Wetsel, W. C., Mains, R. E., and Eipper, B. A. (2013) Peptidylglycine alpha-amidating monooxygenase heterozygosity alters brain copper handling with region specificity. J Neurochem 127, 605-619
51. Yeh, S., Ralle, M., Phan, I. T., Francis, P. J., Rosenbaum, J. T., and Flaxel, C. J. (2012) Occult intraocular foreign body masquerading as panuveitis: inductively coupled mass spectrometry and electrophysiologic analysis. J Ophthalmic Inflamm Infect 2, 99-103
52. Vyleta, M. L., Wong, J., and Magun, B. E. (2012) Suppression of ribosomal function triggers innate immune signaling through activation of the NLRP3 inflammasome. PloS one 7, e36044-e36044
53. Gray, L. W., Peng, F., Molloy, S. A., Pendyala, V. S., Muchenditsi, A., Muzik, O., Lee, J., Kaplan, J. H., and Lutsenko, S. (2012) Urinary copper elevation in a mouse model of Wilson's disease is a regulated process to specifically decrease the hepatic copper load. PloS one 7, e38327-e38327
54. Gaier, E. D., Kleppinger, A., Ralle, M., Mains, R. E., Kenny, A. M., and Eipper, B. A. (2012) High serum Cu and Cu/Zn ratios correlate with impairments in bone density, physical performance and overall health in a population of elderly men with frailty characteristics. Exp Gerontol 47, 491-496
55. Quinn, J. F., Harris, C., Kaye, J. A., Lind, B., Carter, R., Anekonda, T., and Ralle, M. (2011) Gender effects on plasma and brain copper. Int J Alzheimers Dis 2011, 150916
56. Burkhead, J. L., Ralle, M., Wilmarth, P., David, L., and Lutsenko, S. (2011) Elevated copper remodels hepatic RNA processing machinery in the mouse model of Wilson's disease. J Mol Biol 406, 44-58
57. Anekonda, T. S., Wadsworth, T. L., Sabin, R., Frahler, K., Harris, C., Petriko, B., Ralle, M., Woltjer, R., and Quinn, J. F. (2011) Phytic acid as a potential treatment for alzheimer's pathology: evidence from animal and in vitro models. J Alzheimers Dis 23, 21-35
58. Quinn, J. F., Harris, C. J., Cobb, K. E., Domes, C., Ralle, M., Brewer, G., and Wadsworth, T. L. (2010) A copper-lowering strategy attenuates amyloid pathology in a transgenic mouse model of Alzheimer's disease. J Alzheimers Dis 21, 903-914