Publications

2024

Astrocyte-dependent local neurite pruning in Beat-Va neurons.
Lehmann KS, Hupp MT, Abalde-Atristain L, Jefferson A, Cheng YC, Sheehan AE, Kang Y, Freeman MR. J Cell Biol. 2025 Jan 6;224(1):e202312043. doi: 10.1083/jcb.202312043. Epub 2024 Dec 9. PMID: 39652106.

The Biology of Glia.
Stevens B, Monk KR, Freeman MR. Cold Spring Harb Perspect Biol. 2024 Sep 16:a041809. doi: 10.1101/cshperspect.a041809. Online ahead of print. PMID: 39284663.

Glial Regulation of Circuit Wiring, Firing, and Expiring in the Drosophila Central Nervous System.
Coutinho-Budd J, Freeman MR, Ackerman S. Cold Spring Harb Perspect Biol. 2024 Dec 2;16(12):a041347. doi: 10.1101/cshperspect.a041347. PMID: 38565270.

Astrocyte growth is driven by the Tre1/S1pr1 phospholipid-binding G protein-coupled receptor. 
Chen J, Stork T, Kang Y, Nardone KAM, Auer F, Farrell RJ, Jay TR, Heo D, Sheehan A, Paton C, Nagel KI, Schoppik D, Monk KR, Freeman MR. Neuron. 2024 Jan 3;112(1):93-112.e10. PMID: 38096817

2023

Glial TGFβ activity promotes neuron survival in peripheral nerves.
Lassetter AP, Corty MM, Barria R, Sheehan AE, Hill JQ, Aicher SA, Fox AN, Freeman MR.
J Cell Biol. 2023 Jan 2;222(1):e202111053.
PMID: 36399182

2022

Discoidin domain receptor regulates ensheathment, survival and caliber of peripheral axons.
Corty MM, Hulegaard AL, Hill JQ, Sheehan AE, Aicher SA, Freeman MR.
Development. 2022 Dec 1;149(23):dev200636
PMID: 36355066

Astrocytic GABA transporter controls sleep by modulating GABAergic signaling in Drosophila circadian neurons.
Chaturvedi R, Stork T, Yuan C, Freeman MR, Emery P.
Curr Biol. 2022 May 9;32(9):1895-1908.e5.
PMID: 35303417

2021

An ELISA-based method for rapid genetic screens in Drosophila.
Jay TR, Kang Y, Jefferson A, Freeman MR.
Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2107427118.
PMID: 34686600

SARM1 signaling mechanisms in the injured nervous system
Sambashivan S, Freeman MR
Curr Opin Neurobiol. 2021 Jun 24;69:247-255
PMID: 34175654

TSG101 negatively regulates mitochondrial biogenesis in axons
Lin TH, Bis-Brewer DM, Sheehan AE, Townsend LN, Maddison DC, Züchner S, Smith GA, Freeman MR
Proc Natl Acad Sci USA 2021 May 18;118(20):e2018770118
PMID: 33972422

Astrocytes close a motor circuit critical period
Ackerman SD, Perez-Catalan NA, Freeman MR, Doe CQ
Nature 2021 Apr;592(7854):414-420
PMID: 33828296

Injury-induced inhibition of bystander neurons requires dSarm and signaling from glia
Hsu JM, Kang Y, Corty MM, Mathieson D, Peters OM, Freeman MR
Neuron 2021 Feb 3;109(3):473-487.e5
PMID: 33296670