What is it about?

Masculinization of the fetus depends on interplay between the brain and gonads. Blocking the testosterone produced by the fetal testes does not fully prevent masculinization of the brain because of compensatory mechanisms. It has not been known whether blocking production of testosterone by the gonads would effectively prevent masculinization of the fetal brain.

Why is it important?

How the brain and gonads develop in the fetus has long-lasting consequences for life.

Find this paper in Endocrinology and in Pubmed.