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Orderable EAP code:

LAB00240

Billable EAP Codes:

80001817 x 1

CPT Codes:

85384 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 2 Hours
Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Units:

mg/dL

Critical Values:

Less than or equal to 50 mg/dL.

Specimen Requirements:

3.2% sodium citrate tubes are acceptable provided they are filled to the line on the manufacturers label. Tubes must be full (see comments below). Whole blood specimens are stable for up to (and including) 4 hours at room temperature. Citrate plasma separated from cells is stable for up to (and including) 14 days at -20 degrees C.

Pediatric Specimen Requirements:

Add blood to the 1.3 mL mark of Pediatric BLUE top tube, 3.2% sodium citrate.

Reference Range:

Reference Range: 150 to 393 mg/dL

Comments:

Draw volume is critical due to the liquid anticoagulant. Allow tubes to fill by vacuum.

Tubes with rubber stopper: fill to line on label.
Tubes with plastic (Hemogard) cap: the fill level is above the top of the label.
Syringe: do not remove the vacutainer stopper. Insert the needle through the stopper and allow the tube to fill by vacuum. Do not overfill the vacutainer.
Pediatric tubes have no vacuum. Remove the cap and add blood to the 1.3 mL mark. Do not overfill.

Clotted specimens are unacceptable.

Synonyms:

Coags
Fibrinogen Level, Quantitative

Orderable EAP code:

LAB00154

Billable EAP Codes:

80003570 x 1

CPT Codes:

82728 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 2 Hours
Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Units:

ng/mL

Specimen Requirements:

4 mL blood in a GREEN top, lithium heparin tube.

Pediatric Specimen Requirements:

0.5 mL blood in a GREEN top, lithium heparin tube.

Reference Range:

Male and Female greater than 18 years:
Less than 20 ng/mL: Consistent with iron deficiency
21 to 50 ng/mL: possible iron deficiency
51 to 99 ng/mL: iron deficiency unlikely unless inflammation present or patient older than 65 years of age
100 to 200 ng/mL: normal, not consistent with iron deficiency
Greater than 200 ng/mL: if transferrin saturation is greater than 45%, consider hemochromatosis

Orderable EAP code:

LAB00256

Billable EAP Codes:

80001094 x 1 (Factor VIII Coag)

CPT Codes:

85240 x 1 (Factor VIII Coag)

Lab Section:

Core Lab

Includes:

Assay is included in the Von Willebrand Panel.

Turnaround Time:

1 Day

Test Schedule:

Batched once per day. Must be in Core Lab by 7:00 AM. Call 503-494-7383 if STAT.

Units:

Specimen Requirements:

3.2% sodium citrate tubes are acceptable when they are filed to the line on the manufacturers label. Tubes must be full (see comments below). For referral testing, submit 2 x 1.0 mL frozen platelet poor citrated plasma.

Sodium citrate specimens must be processed and frozen within 2 hours of specimen collection.

OHSU clinics must cab specimen to the Core Lab, Hatfield Research Center (HRC), Room 9D05 if processing is delayed or not possible on site. A phone call is helpful to alert the lab at 503-494-5764.

Detailed instructions are under the Hemostasis & Thrombosis section (Opens in a new window).

Pediatric Specimen Requirements:

Add blood to the 1.3 mL mark of Pediatric BLUE top tube, 3.2% sodium citrate. For pediatric patients requiring multiple coagulation tests, please call 503-494-7383 regarding draw volumes.

Reference Range:

Reference Range: 50% to 150%

Comments:

Draw volume is critical due to the liquid anticoagulant. Allow tubes to fill by vacuum.

Tubes with rubber stopper: fill to line on label.
Tubes with plastic (Hemogard) cap: the fill level is above the top of the label.
Syringe: do not remove the vacutainer stopper. Insert the needle through the stopper and allow the tube to fill by vacuum. Do not overfill the vacutainer.
Pediatric tubes have no vacuum. Remove the cap and add blood to the 1.3 mL mark. Do not overfill.

Avoid warfarin (Coumadin) therapy for 2 weeks and heparin therapy for 2 days prior to the test.

Use: detect coagulant factor VIII deficiency. Factor VIII deficiency (Hemophilia A) is the most common of the hereditary bleeding disorders. Deficiences of factor VIII are inherited as sex-linked recessive disorders. Factor VIII is a molecular complex consisting of VIII:C, which corrects the abnormal clotting time, and VIII:R the "related protein" (the von Willebrand protein) which corrects the defect in von Willebrand disease. VIII:C portion of the complex is a glycoprotein with molecular weight of about 285,000. There are both VIII:C deficient patients (CRM-type also named hemophilia A-, the common form) and VIII:C nonfunctional molecular variant patients (CRM+ type also named hemophilia A+).

Female patients with VWD on oral contraceptives or who are pregnant may have normal F. VIII values. F. VIII is also an acute-phase reactant and is elevated with stress or exercise.

Synonyms:

F8A
Factor 8
Factor VIII
FVIIIA

Orderable EAP code:

LAB00255

Billable EAP Codes:

80001093 x 1 (Factor IX Activity)

CPT Codes:

85250 x 1 (Factor IX Activity)

Lab Section:

Core Lab

Turnaround Time:

Routine: 1 Day
Urgent: N/A

Test Schedule:

Batched daily 7 days per week. Please call 503-494-5764 if STAT.

Units:

Specimen Requirements:

Sodium citrate specimens must be processed and frozen within 2 hours of specimen collection.

OHSU clinics must cab specimen to the Core Lab, Hatfield Research Center (HRC), Room 9D05 if processing is delayed or not possible on site. A phone call is helpful to alert the lab at 503-494-5764.

Detailed instructions are under Hemostasis & Thrombosis section (Opens in a new window).

Pediatric Specimen Requirements:

Add blood to the 1.3 mL mark of Pediatric BLUE top tube, 3.2% sodium citrate. For pediatric patients requiring multiple coagulation tests, please call 503-494-7383 regarding draw volumes.

Reference Range:

Reference Range: 65% to 150%

Comments:

Draw volume is critical due to the liquid anticoagulant. Allow tubes to fill by vacuum.

Tubes with rubber stopper: fill to line on label.
Tubes with plastic (Hemogard) cap: the fill level is above the top of the label.
Syringe: do not remove the vacutainer stopper. Insert the needle through the stopper and allow the tube to fill by vacuum. Do not overfill the vacutainer.
Pediatric tubes have no vacuum. Remove the cap and add blood to the 1.3 mL mark. Do not overfill.

Avoid warfarin (Coumadin) therapy for 2 weeks and heparin therapy for 2 days prior to the test.

Assay to document Factor IX deficiency. Factor IX deficiency (PTC or plasma thromboplastin component or Christmas disease) is commonly referred to as hemophilia B. It has a recessive sex-linked mode of inheritance, males are affected, females are carriers. It occurs in 1 of 25,000 males. Low levels of factor IX may be present in patients with liver disease. Severity of the symptoms correlate directly with the degree of prolongation of APTT test (level of factor IX deficiency). Mildly affected patient may show excessive bleeding only with major trauma or surgery. The APTT may not be prolonged if the factor IX level is over 25%. In most cases of hemophilia B, the prothrombin time and thrombin times are normal. A subgroup of cross reacting material positive hemophilia B patients, however, is defined by its markedly prolonged ox-brain prothrombin time. The molecular defect of this "hemophilia Bm" (factor IXHilo) has recently been described. Methodology: APTT based clotting assay.

Synonyms:

F9A
Factor IX
Factor 9

Orderable EAP code:

LAB00073

Billable EAP Codes:

80005565 x 1

CPT Codes:

82077 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 2 Hours
Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Units:

mg/dL

Critical Values:

Greater than or equal to 400 mg/dL

Specimen Requirements:

4 mL blood in a GREEN top, lithium heparin tube.

Reference Range:

Negative

Comments:

Methanol, isopropanol, and acetone are not measured.
Oregon legal limit 0.08 g/dL, 80 mg/dL

Synonyms:

ETOH, Alcohol (Ethanol), Blood Alcohol Level

Orderable EAP code:

LAB00234

Billable EAP Codes:

80001821 x 1

CPT Codes:

85652 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 2 Hours
Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Units:

mm/hr

Specimen Requirements:

3.0 mL blood in a LAVENDER top tube.

Specimen stability: 4 hours at room temperature, 24 hours refrigerated. Do not freeze.

Pediatric Specimen Requirements:

1.0 mL blood in a 3 mL LAVENDER top tube

Submit all sed rate specimens, even low volume peds specimens, in standard size EDTA tubes. Microtainers are not compatible with instrumentation used to measure sed rate.

Specimen stability: 4 hours at room temperature, 24 hours refrigerated. Do not freeze.

Reference Range:

Age	Male	Female
0 days to 50 years	0 to 15 mm/hr	0 to 20 mm/hr
50 years to 150 years	0 to 20 mm/hr	0 to 30 mm/hr

Comments:

Clotted specimens are unacceptable.

Conditions such as cold agglutinins, anemia (including sickle cell disease), multiple myeloma, hemolysis, icterus or lipemia may affect sedimentation rate results.

Synonyms:

ESR, SED Rate, Westergren ESR

Orderable EAP code:

LAB00330

Billable EAP Codes:

80001836 x 1

CPT Codes:

89051 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 2 Hours
Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Units:

% Eosinophils/100 cells counted.

Specimen Requirements:

12 mL urine in a clean cup.

Pediatric Specimen Requirements:

1 mL urine in a clean cup.

Reference Range:

None seen.

Orderable EAP code:

LAB00370

Billable EAP Codes:

80001839 x 1

CPT Codes:

89190 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 2 Hours
Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Units:

% Eosinophils/100 cells counted.

Specimen Requirements:

2 dry nasal secretion smears on slides or swab or exudate in sterile container.

Reference Range:

None seen.

Synonyms:

Eosinophils, Exudate

Orderable EAP code:

LAB102855

Billable EAP Codes:

80002909 x 1

CPT Codes:

87498 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 4 Hours
Urgent: 2 Hours

Test Schedule:

24 hours, 7 days a week.

Critical Values:

Positive for Enterovirus by PCR

Specimen Requirements:

0.5 mL CSF in sterile container. STAT to lab.

Reference Range:

Negative

Comments:

Positive enterovirus results do not rule out other causes of meningitis including bacteria, fungi and other viruses. Negative enterovirus results do not entirely rule out enterovirus as a cause of meningitis, as virus, if present, may be below detection levels. Does not detect Parechovirus.

Orderable EAP code:

LAB00430

Billable EAP Codes:

80001655 x 1

CPT Codes:

80051 x 1

Lab Section:

Core Lab

Includes:

Na, K, Cl, CO2

Turnaround Time:

Routine: 2 Hours
Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Critical Values:

See individual test listings for critical values.

Specimen Requirements:

4 mL blood in a GREEN top, lithium heparin tube.

Pediatric Specimen Requirements:

0.5 mL in a 1.0 mL GREEN top, lithium heparin tube.

Reference Range:

See individual test listings for reference ranges.

Synonyms:

Electrolyte

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