Opiate/Oxycodone Confirm Quantitative, Urine

Orderable EAP code:

LAB100064

Billable EAP Codes:

80002007 x 1
80004402 x 1

CPT Codes:

80361 x 1
80365 x 1

Lab Section:

Biochemical Genetics

Includes:

Codeine, Morphine, Hydrocodone, Hydromorphone, Oxycodone, Oxymorphone, and 6-Acetylmorphine (qualitative).

Turnaround Time:

7 to 10 Days

Test Schedule:

Twice per week

Units:

ng/mL

Specimen Requirements:

1 mL (100 microliters minimum) urine in sample cup. Stable 3 days ambient, 14 days refrigerated, 14 days frozen.

Pediatric Specimen Requirements:

1 mL (100 microliters minimum) urine in sample cup. Stable 3 days ambient, 14 days refrigerated, 14 days frozen.

Reference Range:

Negative

Comments:

Opiate detection window 2 to 3 days.

Confirmation Cut-off:
Hydrocodone, Codeine, Oxycodone, Oxymorphone, Morphine, and Hydromorphone by LC-MS: greater than 50 ng/mL
6-Acetylmorphine: positive if greater than 10 ng/mL
Presence of 6-Acetylmorphine (6-AM) is suggestive of heroin ingestion.

Certain synthetic and natural opiates are not detected by this method. The compounds not detected include, but are not limited, to the following: Demerol (meperidine), Fentanyl, Thebaine, Etorphine, Oripavine, Norcodeine, Nalbuphine, Buprenorphine, Naloxone and Naltrexone. Morphine-glucuronide and codeine-glucuronide are metabolic products of morphine and codeine respectively.
Identification of specific drug(s) taken by specimen donor is problematic due to common metabolites, some of which are prescription drugs themselves. The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. A very small amount of an unexpected drug analyte in the presence of a large amount of an expected drug analyte may reflect pharmaceutical impurity. Interpretive questions should be directed to the laboratory.

Results confirmed by mass spectroscopy. This is a lab-developed test not evaluated by the FDA. These results are for clinical use only.
 

Synonyms:

Opiate Confirmation