Platelet Aggregations with ATP Release
Orderable EAP code:
Billable EAP Codes:
CPT Codes:
Lab Section:
Turnaround Time:
1 day
Test Schedule:
Specimen must be collected at OHSU PPV or DCH by appointment only. Schedule with Lab Client Services 503-494-7383. Schedule appointments Tuesdays, 9:00 to 12:00, at least 1 hour apart and no more than 3 per day.
Specimen Requirements:
Patients should refrain from non-steroidal anti-inflammatory drugs, aspirin and aspirin containing products, (unless the patient is being checked for aspirin resistance) or dietary supplements known to affect platelet function 10-14 days prior to testing.
Four FULL 2.7 mL whole blood LIGHT BLUE (3.2% sodium citrate) tubes and one 3 mL whole blood LAVENDER (EDTA). Do NOT send in pneumatic tube system. Do NOT spin.
Stability is 3 hours at Room Temperature.
Sample must be received in SIC Lab within 1 hour of the draw.
Pediatric Specimen Requirements:
Patients should refrain from non-steroidal anti-inflammatory drugs, aspirin and aspirin containing products, (unless the patient is being checked for aspirin resistance) or dietary supplements known to affect platelet function 10-14 days prior to testing.
Three FULL 2.7 mL whole blood LIGHT BLUE (3.2% sodium citrate) tubes and one 3 mL whole blood LAVENDER (EDTA). Do NOT send in pneumatic tube system. Do NOT spin.
Stability is 3 hours at Room Temperature.
Sample must be received in SIC Lab within 1 hour of the draw.
For pediatric patients requiring multiple coagulation tests, please call 503-494-7383 regarding draw volumes.
Reference Range:
Thrombin ATP Release (1 Unit/mL) greater than 0.5 nmole
Ristocetin Aggregation (0.25mg/mL) less than 5 Ohms
Ristocetin Aggregation (1.0mg/mL) greater than 5 Ohms
Collagen Aggregation (1ug/mL) 12 to 33 Ohms
Collagen ATP Release (1ug/mL) 0.5 to 1.7 nmole
Collagen Aggregation (5ug/mL) 17 to 42 Ohms
Collagen ATP Release (5ug/mL) 0.7 to 2.4 nmole
ADP Aggregation (10uM) 10 to 31 Ohms
ADP ATP Release (10uM) 0.35 to 1.4 nmole
Arachidonic Acid Aggregation (0.5mM) 10 to 32 Ohms
Arachidonic Acid ATP Release (0.5mM) 0.44 to 2.0 nmole
Comments:
This test is to screen for specific hereditary and acquired platelet functional abnormalities such as rare congenital disorders (Glanzmann's thrombasthenia and Bernard-Soulier syndrome).
Synonyms:
Aggregation
Plt Agg