PNH Test (High Sensitivity)

Orderable EAP code:

LAB00299, LAB101194

Billable EAP Codes:

80002141 x 1 (First)
80002129 x 7 (Additional)
88187 x 1 (Profee for each read)

CPT Codes:

88185 x 1 (First)
88184 x 7 (Additional)
88187 x 1 (Profee for each read)

Lab Section:

Flow Cytometry

Turnaround Time:

Routine: 5 days

Test Schedule:

Monday through Friday, 8:00 am to 4:30 pm.

Specimen Requirements:

6 mL blood in one full 6 mL LAVENDER top (EDTA) tube required.
Samples should be received and processed within 48 hours.

Pediatric Specimen Requirements:

4 mL blood in one full 4 mL LAVENDER top (EDTA) tube required.
Samples should be received and processed within 48 hours.

Comments:

Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) have a defect in the pig-a gene and lack glycosylphosphatidylinositol (GPI) anchored proteins including CD59 (membrane inhibitor of reactive lysis) which protects cells from complement mediated lysis. This test measures the presence or absence of CD59 by flow cytometry. A consultative report will be sent. 

Synonyms:

Paroxysmal Nocturnal Hemoglobinuria
PIG-A Gene Function For PNH
PNH by Flow