Tacrolimus

Orderable EAP code:

LAB00287

Billable EAP Codes:

80002112 x 1

CPT Codes:

80197 x 1

Lab Section:

Immunology

Turnaround Time:

Routine: 1 day

Test Schedule:

Monday through Friday.

Units:

ng/mL

Critical Values:

20 ng/mL or greater.

Specimen Requirements:

3 mL blood in a LAVENDER top (EDTA) tube; redraw if the specimen is clotted. 
Stable for 48 hours at room temperature or for 7 days refrigerated (2 to 8 degrees Celsius). If testing is delayed more than 7 days, store frozen at -10 degrees Celsius or less.

Pediatric Specimen Requirements:

0.5 mL blood in a pediatric LAVENDER top (EDTA) tube.

Reference Range:

Therapeutic range: 5 to 15 ng/mL

Comments:

Test performed by immunoassay using Abbott Architect i2000.

Samples for analysis of Tacrolimus should be collected 30 minutes to 1 hour prior to the next dose so that the measured concentration of drug represents trough level. Some other factors influencing therapeutic range, dose administered, and result interpretation include time since transplantation, the organ transplanted, co-administration of other immunosuppressants and interaction with other drugs that may increase or decrease Tacrolimus concentrations.

Synonyms:

FK506 (Tacrolimus), Whole Blood