Chen Lab

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Welcome to the Yabing Chen Lab Page!

Mission

We strive to cultivate a diverse, equitable and vibrant academic environment that promotes innovative scientific discovery with collaborative teamwork and supports career advancement of all members with different career goals.

Research Overview

To discover novel molecular and cellular mechanisms regulating vascular smooth muscle cell phenotypic modulation and transdifferentiation and its cross-talk with other cells in the pathogenesis of cardiovascular diseases and aging.

Join Our Team

We are recruiting Research Staff, Graduate Students and Postdocs!

Arterioscler Thromb Vasc Biol. 2023 Jan
Arterioscler Thromb Vasc Biol. 2023 Jan;43(1):15-29

Research Projects

  1. Elucidate an essential role of oxidative stress-induced Runx2 in regulating vascular smooth muscle cell osteogenic differentiation and vascular calcification in atherosclerosis, diabetic vasculopathy and vascular aging.
  2. Discover the novel mechanisms underlying vascular osteoclasts in atherosclerotic vascular calcification.
  3. Discover the regulation of protein O-GlcNAcylation in vascular smooth muscle cell osteogenic differentiation and calcification in diabetes.
  4. Elucidate the molecular mechanisms underlying vascular smooth muscle cell phenotypic switch in pan-vascular pathology and their contribution to cognitive impairments and dementia.

Lab Members

Current members

Yabing Chen, PhD, MBA, FAHA

Yabing Chen, PhD, MBA, FAHA
Professor and Vice Chair for Research
Department of Pathology and Laboratory Medicine
chenyab@ohsu.edu

Contact

Richard Jones Hall Biomedical Research Building, Room 1386
3222 SW Research Dr
Portland, OR 97239
P: 503.494.1547

Links