About us

The Integrated Pathology Core (IPC) provides investigators with state-of-the-art histology and advanced optical light microscopy imaging and analysis through extensive expertise, services, data analysis, and access to advanced equipment. Services provided include routine histology, cryosectioning, immunohistochemistry, next-generation RNAScope/DNAScope in situ hybridization, advanced optical light (bright field and multi-spectral confocal) microscopy, digital whole-slide imaging, and quantitative image analysis. Core personnel are available at every stage of histology and microscopy-based experiments, from planning to training, troubleshooting, and quality control.

The Core has an extensive resource of tissue-based analyses and techniques including multiplexed immunohistochemical and immunofluorescence staining and RNA/DNAScope in situ hybridization. In addition to routine and automated histology equipment, advanced histology techniques are supported by a Biocare IntelliPATH automated stainer for immunohistochemistry. Imaging and microscopy capabilities include a Leica Stellaris 8 confocal, Leica Aperiao AT2 bright field slide scanner, Olympus VS120 fluorescence (up to 5 channels) and Bright field slide scanner with multiple slide inserts, and a Keyence BZ-X810 Fluorescence Microscope.  Image analysis is supported by multiple platforms including the HALO Image Analysis suite (Indica Lab, Corrales, NM), an advanced quantitative image analysis package that supports unique tissue-specific and disease-specific applications.