Alex Nechiporuk, Ph.D.

  • Professor of Cell, Developmental and Cancer Biology, School of Medicine
  • Cell and Developmental Biology Graduate Program, School of Medicine
  • Neuroscience Graduate Program, School of Medicine
  • Program in Molecular and Cellular Biosciences, School of Medicine
  • Cancer Biology Graduate Program, School of Medicine

Education and training

  • Degrees

    • Ph.D., 2002, University of Utah

Memberships and associations:

  • Society for Developmental Biology
  • American Society for Cell Biology

Areas of interest

  • zebrafish axonal transport neuron development lateral line sensory systems

Publications

Publications

  • RhoA GEF Mcf2lb regulates rosette integrity during collective cell migration

    Development (Cambridge)
    1. Hannah M. Olson
    2. Amanda Maxfield
    3. Nicholas L. Calistri
    4. Laura M. Heiser
    5. Weiyi Qian
    6. Holger Knaut
    7. Alex V. Nechiporuk
  • Single-Cell Analysis of Rohon-Beard Neurons Implicates Fgf Signaling in Axon Maintenance and Cell Survival

    Journal of Neuroscience
    1. Adam M. Tuttle
    2. Lauren N. Miller
    3. Lindsey J. Royer
    4. Hua Wen
    5. Jimmy J. Kelly
    6. Nicholas L. Calistri
    7. Laura M. Heiser
    8. Alex V. Nechiporuk
  • c-Kit Receptor Maintains Sensory Axon Innervation of the Skin through Src Family Kinases

    Journal of Neuroscience
    1. Adam M. Tuttle
    2. Matthew B. Pomaville
    3. Katherine C. Delgado
    4. Kevin Wright
    5. Alex V. Nechiporuk
  • NudC regulated Lis1 stability is essential for the maintenance of dynamic microtubule ends in axon terminals

    iScience
    1. Dane Kawano
    2. Katherine Pinter
    3. Madison Chlebowski
    4. Ronald S. Petralia
    5. Ya Xian Wang
    6. Alex V. Nechiporuk
    7. Catherine M. Drerup
  • Lamellipodia-like protrusions and focal adhesions contribute to collective cell migration in zebrafish

    Developmental Biology
    1. Hannah M. Olson
    2. Alex V. Nechiporuk
  • HDAC1-mediated repression of the retinoic acid-responsive gene ripply3 promotes second heart field development

    PLoS genetics
    1. Yuntao Charlie Song
    2. Tracy E. Dohn
    3. Ariel B. Rydeen
    4. Alex V. Nechiporuk
    5. Joshua S. Waxman
  • Retrograde ret signaling controls sensory pioneer axon outgrowth

    eLife
    1. Adam Tuttle
    2. Catherine M. Drerup
    3. Molly Marra
    4. Hillary McGraw
    5. Alex V. Nechiporuk
  • The Paf1 complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors

    Development (Cambridge)
    1. Michael J. Jurynec
    2. Xiaoying Bai
    3. Brent W. Bisgrove
    4. Haley Jackson
    5. Alex Nechiporuk
    6. Rebecca A.S. Palu
    7. Hannah A. Grunwald
    8. Yi Chu Su
    9. Kazuyuki Hoshijima
    10. H. Joseph Yost
    11. Leonard I. Zon
    12. David Jonah Grunwald
  • Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo

    Proceedings of the National Academy of Sciences of the United States of America
    1. Amy L. Herbert
    2. Meng Meng Fu
    3. Catherine M. Drerup
    4. Ryan S. Gray
    5. Breanne L. Harty
    6. Sarah D. Ackerman
    7. Thomas O'Reilly-Pol
    8. Stephen L. Johnson
    9. Alex V. Nechiporuk
    10. Ben A. Barres
    11. Kelly R. Monk
  • Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by transmembrane o-methyltransferase (Tomt)

    eLife
    1. Timothy Erickson
    2. Clive P. Morgan
    3. Jennifer Olt
    4. Katherine Hardy
    5. Elisabeth Busch-Nentwich
    6. Reo Maeda
    7. Rachel Clemens
    8. Jocelyn F. Krey
    9. Alex Nechiporuk
    10. Peter G. Barr-Gillespie
    11. Walter Marcotti
    12. Teresa Nicolson
  • Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons

    eLife
    1. Catherine M. Drerup
    2. Amy L. Herbert
    3. Kelly R. Monk
    4. Alex V. Nechiporuk
  • Kif1B interacts with KBP to promote axon elongation by localizing a microtubule regulator to growth cones

    Journal of Neuroscience
    1. Catherine M. Drerup
    2. Sarah Lusk
    3. Alex Nechiporuk
  • Kremen1 restricts Dkk activity during posterior lateral line development in zebrafish

    Development (Cambridge)
    1. Hillary F. McGraw
    2. Maya D. Culbertson
    3. Alex V. Nechiporuk
  • Fgf3 and Fgf10a work in concert to promote maturation of the epibranchial placodes in Zebrafish

    PloS one
    1. Matthew N. McCarroll
    2. Alex V. Nechiporuk
  • JNK-Interacting Protein 3 Mediates the Retrograde Transport of Activated c-Jun N-Terminal Kinase and Lysosomes

    PLoS genetics
    1. Catherine M. Drerup
    2. Alex V. Nechiporuk
  • Fgfr-Ras-MAPK signaling is required for apical constriction via apical positioning of Rho-associated kinase during mechanosensory organ formation

    Development (Cambridge)
    1. Molly J. Harding
    2. Alex V. Nechiporuk
  • Graded levels of Pax2a and Pax8 regulate cell differentiation during sensory placode formation.

    Development (Cambridge, England)
    1. Matthew N. McCarroll
    2. Zachary R. Lewis
    3. Maya Deza Culbertson
    4. Benjamin L. Martin
    5. David Kimelman
    6. Alex V. Nechiporuk
  • Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing

    Development (Cambridge)
    1. Nikolaus Obholzer
    2. Ian A. Swinburne
    3. Evan Schwab
    4. Alex V. Nechiporuk
    5. Teresa Nicolson
    6. Sean G. Megason
  • Chondrogenic and gliogenic subpopulations of neural crest play distinct roles during the assembly of epibranchial ganglia

    PloS one
    1. Maya D. Culbertson
    2. Zachary R. Lewis
    3. Alexei V. Nechiporuk
  • Lef1 is required for progenitor cell identity in the zebrafish lateral line primordium

    Development
    1. Hillary F. McGraw
    2. Catherine M. Drerup
    3. Maya D. Culbertson
    4. Tor Linbo
    5. David W. Raible
    6. Alexei V. Nechiporuk
  • Zebrafish mnx1 controls cell fate choice in the developing endocrine pancreas

    Development
    1. Gokhan Dalgin
    2. Andrea B. Ward
    3. le T. Hao
    4. Christine E. Beattie
    5. Alexei Nechiporuk
    6. Victoria E. Prince
  • Quantification of vestibular-induced eye movements in zebrafish larvae.

    BMC neuroscience
    1. Weike Mo
    2. Fangyi Chen
    3. Alex Nechiporuk
    4. Teresa Nicolson
  • FGF-dependent mechanosensory organ patterning in zebrafish

    Science
    1. Alex Nechiporuk
    2. David W. Raible
  • Vesicular glutamate transporter 3 is required for synaptic transmission in zebrafish hair cells

    Journal of Neuroscience
    1. Nikolaus Obholzer
    2. Sean Wolfson
    3. Josef G. Trapani
    4. Weike Mo
    5. Alex Nechiporuk
    6. Elisabeth Busch-Nentwich
    7. Christoph Seiler
    8. Samuel Sidi
    9. Christian Söllner
    10. Robert N. Duncan
    11. Andrea Boehland
    12. Teresa Nicolson
  • Zebrafish dorsal root ganglia neural precursor cells adopt a glial fate in the absence of neurogenin1

    Journal of Neuroscience
    1. Hillary F. McGraw
    2. Alexei Nechiporuk
    3. David W. Raible
  • Specification of epibranchial placodes in zebrafish

    Development
    1. Alexei Nechiporuk
    2. Tor Linbo
    3. Kenneth D. Poss
    4. David W. Raible