Publications

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Analysis of K-Ras Interactions by Biotin Ligase Tagging.
Ritchie C, Mack A, Harper L, Alfadhli A, Stork PJS, Nan X, Barklis E.
Cancer Genomics Proteomics. 2017 Jul-Aug;14(4):225-239.
PMID: 28647697 [PubMed - in process]

Analysis of quinolinequinone reactivity, cytotoxicity, and anti-HIV-1 properties.
Alfadhli A, Mack A, Harper L, Berk S, Ritchie C, Barklis E.
Bioorg Med Chem. 2016 Nov 1;24(21):5618-5625. doi: 10.1016/j.bmc.2016.09.028. Epub 2016 Sep 12.
PMID: 27663546 [PubMed - indexed for MEDLINE]

Trimer Enhancement Mutation Effects on HIV-1 Matrix Protein Binding Activities.
Alfadhli A, Mack A, Ritchie C, Cylinder I, Harper L, Tedbury PR, Freed EO, Barklis E.
J Virol. 2016 May 27;90(12):5657-64. doi: 10.1128/JVI.00509-16. Print 2016 Jun 15.
PMID: 27030269 [PubMed - indexed for MEDLINE] Free PMC Article

The roles of lipids and nucleic acids in HIV-1 assembly.
Alfadhli A, Barklis E.
Front Microbiol. 2014 May 28;5:253. doi: 10.3389/fmicb.2014.00253. eCollection 2014. Review.
PMID: 24917853 [PubMed] Free PMC Article

Analysis of small molecule ligands targeting the HIV-1 matrix protein-RNA binding site.
Alfadhli A, McNett H, Eccles J, Tsagli S, Noviello C, Sloan R, López CS, Peyton DH, Barklis E.
J Biol Chem. 2013 Jan 4;288(1):666-76. doi: 10.1074/jbc.M112.399865. Epub 2012 Nov 7.
PMID: 23135280 [PubMed - indexed for MEDLINE] Free PMC Article

HIV-1 matrix protein binding to RNA.
Alfadhli A, McNett H, Tsagli S, Bächinger HP, Peyton DH, Barklis E.
J Mol Biol. 2011 Jul 22;410(4):653-66. doi: 10.1016/j.jmb.2011.04.063.
PMID: 21762806 [PubMed - indexed for MEDLINE] Free PMC Article

Analysis of human immunodeficiency virus type 1 matrix binding to membranes and nucleic acids.
Alfadhli A, Still A, Barklis E.
J Virol. 2009 Dec;83(23):12196-203. doi: 10.1128/JVI.01197-09. Epub 2009 Sep 23.
PMID: 19776118 [PubMed - indexed for MEDLINE] Free PMC Article

Characterization of the in vitro HIV-1 capsid assembly pathway.
Barklis E, Alfadhli A, McQuaw C, Yalamuri S, Still A, Barklis RL, Kukull B, López CS.
J Mol Biol. 2009 Mar 27;387(2):376-89. doi: 10.1016/j.jmb.2009.01.058. Epub 2009 Feb 3.
PMID: 19356593 [PubMed - indexed for MEDLINE] Free PMC Article

HIV-1 matrix organizes as a hexamer of trimers on membranes containing phosphatidylinositol-(4,5)-bisphosphate.
Alfadhli A, Barklis RL, Barklis E.
Virology. 2009 May 10;387(2):466-72. doi: 10.1016/j.virol.2009.02.048. Epub 2009 Mar 27.
PMID: 19327811 [PubMed - indexed for MEDLINE] Free PMC Article

Sultam thiourea inhibition of West Nile virus.
Barklis E, Still A, Sabri MI, Hirsch AJ, Nikolich-Zugich J, Brien J, Dhenub TC, Scholz I, Alfadhli A.
Antimicrob Agents Chemother. 2007 Jul;51(7):2642-5. Epub 2007 Apr 23.
PMID: 17452483 [PubMed - indexed for MEDLINE] Free PMC Article

Human immunodeficiency virus type 1 matrix protein assembles on membranes as a hexamer.
Alfadhli A, Huseby D, Kapit E, Colman D, Barklis E.
J Virol. 2007 Feb;81(3):1472-8. Epub 2006 Nov 15.
PMID: 17108052 [PubMed - indexed for MEDLINE] Free PMC Article

Analysis of human immunodeficiency virus type 1 Gag dimerization-induced assembly.
Alfadhli A, Dhenub TC, Still A, Barklis E.
J Virol. 2005 Dec;79(23):14498-506.
PMID: 16282449 [PubMed - indexed for MEDLINE] Free PMC Article

Assembly of human immunodeficiency virus precursor gag proteins.
Huseby D, Barklis RL, Alfadhli A, Barklis E.
J Biol Chem. 2005 May 6;280(18):17664-70. Epub 2005 Feb 25.
PMID: 15734744 [PubMed - indexed for MEDLINE] Free Article

Hantavirus nucleocapsid protein coiled-coil domains.
Alfadhli A, Steel E, Finlay L, Bächinger HP, Barklis E.
J Biol Chem. 2002 Jul 26;277(30):27103-8. Epub 2002 May 17.
PMID: 12019266 [PubMed - indexed for MEDLINE] Free Article

Effects of diabetes insipidus mutations on neurophysin folding and function.
Eubanks S, Nguyen TL, Deeb R, Villafania A, Alfadhli A, Breslow E.
J Biol Chem. 2001 Aug 10;276(32):29671-80. Epub 2001 Jun 6.
PMID: 11395505 [PubMed - indexed for MEDLINE] Free Article

Hantavirus nucleocapsid protein oligomerization.
Alfadhli A, Love Z, Arvidson B, Seeds J, Willey J, Barklis E.
J Virol. 2001 Feb;75(4):2019-23.
PMID: 11160704 [PubMed - indexed for MEDLINE] Free PMC Article