Donald F. Conrad, Ph.D.

  • Associate Professor, Oregon National Primate Research Center
  • Chief, Division of Genetics, Oregon National Primate Research Center

Biography

Don Conrad, Ph.D. was recruited to OHSU in 2018 as chief of the newly established Division of Genetics at the Primate Center. He is a broadly trained human geneticist with over 15 years of experience in developing statistical and experimental methods for genome analysis. He obtained a Ph.D. in Human Genetics from the University of Chicago, studying with Dr. Jonathan Pritchard, and then did three years of post-doctoral training with Dr. Matthew Hurles at the Wellcome Trust Sanger Institute in Cambridge, UK. Before joining OHSU, Dr. Conrad was faculty at Washington University in St. Louis where he ran his own research group in the Department of Genetics, and was promoted to Associate Professor in 2017.

Dr. Conrad’s early career involved pioneering work in genome-scale analysis of DNA copy number variation (CNV), during which time he played a major role in mapping CNVs for numerous international genetics consortia and published what still stands as the highest resolution array-based map of human copy number variation. As a post-doc at the Sanger Institute he led the first analysis to compare the germline mutation rate among human families using whole genome sequencing.

Dr. Conrad is currently PI on two projects funded by the NIH. The first is to continue development of DeNovoGear, a software package for detecting de novo mutations from families, tissues and single cells, funded by NHGRI. The second is the GEMINI project, an international clinical consortium focusing on the genetics of male infertility, funded by NICHD. To date, GEMINI has exome sequenced about 1,000 cases of male infertility, and is now performing functional follow-up experiments on dozens of potentially novel genetic causes of infertility using animal models. As part of his involvement in GEMINI, Don is devising statistical methods for using large databases of genetic variation to assess the statistical significance of potential causal mutations in n=1 cases of rare disease.

The Conrad lab has a special interest in testis biology and has done work on a) developing methods for multiplex in vivo functional characterization of genes in testicular germ cells using shRNA and CRISPR b) purifying testicular cell populations c) mapping functional elements of germ cells genomes d) characterizing testis pathology using single cell RNA sequencing e) investigating the role of the immune system in regulation of spermatogenesis. Some of this work will be transitioned to non-human primates in order to capitalize on the environment at ONPRC.

Education and training

  • Degrees

    • A.B., 1999, Biochemistry and Molecular Biology - Dartmouth College
    • M.Sc., 2000, Epidemiology, Stanford School of Medicine
    • Ph.D., 2007, Human Genetics, The University of Chicago
  • Fellowship

    • Postdoctoral fellow, Wellcome Trust Sanger Institute, Cambridge, UK, 2007-2010

Memberships and associations:

  • American Society of Human Genetics, 2005-present
  • American Society of Andrology, 2010-present
  • Editorial board of Andrology, 2012-present
  • Editorial board of Biology of Reproduction, 2013-present
  • Editorial board of Genome Research, 2014-present
  • Society for the Study of Reproduction, 2018-present

Areas of interest

  • Human genetics
  • DNA mutation
  • Infertility
  • Genome biology of germ cells
  • Single-cell genomics

Honors and awards

  • Fulbright Specialist Grant, 2017
  • Finalist for Postdoctoral Trainee (Basic) award, ASHG, 2008
  • Best Dissertation in Biological Sciences (honorable mention), The University of Chicago, 2008

Publications

Selected publications

  • Chiang C, Scott AJ, Davis JR, Tsang EK, Li X, Kim Y, Hadzic T, Damani FN, Ganel L, GTEx Consortium, Montgomery SB, Battle A, Conrad DF, Hall IM. The impact of structural variation on human gene expression. Nat Genet. 2017 May; 49(5):692-699. PMC5406250.
  • Ho NR, Usmani AR, Yin Y, Ma L, Conrad DF. Multiplex shRNA Screening of Germ Cell Development by in Vivo Transfection of Mouse Testis. G3 (Bethesda). 2017 Jan 5;7(1):247-255. PMC5217113.
  • Wilfert AB, Chao KR, Kaushal M, Jain S, Zollner S, Adams DR, Conrad DF. Genome-wide significance testing of variation from single case exomes. Nat Genet. 2016 Dec;48(12):1455-1461. PMC5127779.
  • MacArthur DG, Manolio TA, Dimmock DP, Rehm HL, Shendure J, Abecasis GR, Adams DR, Altman RB, Antonarakis SE, Ashley EA, Barrett JC, Biesecker LG, Conrad DF, Cooper GM, Cox NJ, Daly MJ, Gerstein MB, Goldstein DB, Hirschhorn JN, Leal SM, Pennacchio LA, Stamatoyannopoulos JA, Sunyaev SR, Valle D, Voight BF, Winckler W, Gunter C. Guidelines for investigating causality of sequence variants in human disease. Nature. 2014. Apr 24;508(7497):469-476. PMC4180223.
  • Ramu A, Noordam MJ, Schwartz RS, Wuster A, Hurles ME, Cartwright RS, Conrad DF. DeNovoGear: indel and point mutation discovery and phasing. Nat Methods 2013 Oct 10(1):985-987. PMC4003501.
  • Lopes A, Aston K, Thompson E, Carvalho F, Gonçalves J, Huang N, Matthiesen R, Noordam MJ, Quintela I, Ramu A, Seabra C, Wilfert AB, Dai J, Downie JM, Fernandes S, Guo X, Sha J, Amorim A, Barros A, Carracedo A, Hu Z, Hurles ME, Moskovtsev S, Ober C, Paduch DA, Schiffman JD, Schlegel PN, Sousa M, Carrell DT, Conrad DF. Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1. PLoS Genetics 2013 Mar
  • Conrad DF, Keebler JE, Depristo MA, Lindsay SJ, Zhang Y, Casals F, Idaghdour Y, Hartl CL, Torroja C, Garimella KV, Zilversmit M, Cartwright R, Rouleau GA, Daly M, Stone EA, Hurles ME, Awadalla P, on behalf of the 1000 genomes project. Variation in genome-wide mutation rates within and between human families. Nat Genet. 2011 Jun 12;43(7):712-714. PMC3322360.
  • Conrad DF, Bird C, Blackburne B, Lindsay S, Mamanova L, Lee C, Turner DJ, Hurles ME. Mutation spectrum revealed by breakpoint sequencing of human germline CNVs. Nat Genet. 2010 May;42(5):385-391. PMC3428939.
  • Conrad DF, Pinto D, Redon R, Feuk L, Gokcumen O, Zhang Y, Aerts J, Andrews TD, Barnes C, Campbell P, Fitzgerald T, Hu M, Ihm CH, Kristiansson K, Macarthur DG, Macdonald JR, Onyiah I, Pang AW, Robson S, Stirrups K, Valsesia A, Walter K, Wei J; Wellcome Trust Case Control Consortium, Tyler-Smith C, Carter NP, Lee C, Scherer SW, Hurles ME. Origins and functional impact of copy number variation in the human genome. Nature. 2010 Apr 1;464(7289):704-712. PMC3330748
  • Conrad DF, Hurles ME. The population genetics of structural variation. Nat Genet. 2007 Jul;39(7 Suppl):S30-6. PMC2716079.

Publications

  • Estimating realized relatedness in free-ranging macaques by inferring identity-by-descent segments

    Proceedings of the National Academy of Sciences of the United States of America
    1. Annika Freudiger
    2. Vladimir M. Jovanovic
    3. Yilei Huang
    4. Noah Snyder-Mackler
    5. Donald F. Conrad
    6. Brian Miller
    7. Michael J. Montague
    8. Hendrikje Westphal
    9. Peter F. Stadler
    10. Stefanie Bley
    11. Julie E. Horvath
    12. Lauren J.N. Brent
    13. Michael L. Platt
    14. Angelina Ruiz-Lambides
    15. Jenny Tung
    16. Katja Nowick
    17. Harald Ringbauer
    18. Anja Widdig
  • PSAP-Genomic-Regions

    Genetic Epidemiology
    1. Marie Sophie C. Ogloblinsky
    2. Ozvan Bocher
    3. Chaker Aloui
    4. Anne Louise Leutenegger
    5. Ozan Ozisik
    6. Anaïs Baudot
    7. Elisabeth Tournier-Lasserve
    8. Helen Castillo-Madeen
    9. Daniel Lewinsohn
    10. Donald F. Conrad
    11. Emmanuelle Génin
    12. Gaëlle Marenne
  • AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans

    Cell Death and Disease
    1. Brendan J. Houston
    2. Joseph Nguyen
    3. D. Jo Merriner
    4. Anne E. O’Connor
    5. Alexandra M. Lopes
    6. Liina Nagirnaja
    7. Corinna Friedrich
    8. Sabine Kliesch
    9. Frank Tüttelmann
    10. Kenneth I. Aston
    11. Donald F. Conrad
    12. Robin M. Hobbs
    13. Jessica E.M. Dunleavy
    14. Moira K. O’Bryan
  • C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line

    Molecular Cell
    1. Ansgar Zoch
    2. Gabriela Konieczny
    3. Tania Auchynnikava
    4. Birgit Stallmeyer
    5. Nadja Rotte
    6. Madeleine Heep
    7. Rebecca V. Berrens
    8. Martina Schito
    9. Yuka Kabayama
    10. Theresa Schöpp
    11. Sabine Kliesch
    12. Brendan Houston
    13. Liina Nagirnaja
    14. Moira K. O'Bryan
    15. Kenneth I. Aston
    16. Donald F. Conrad
    17. Juri Rappsilber
    18. Robin C. Allshire
    19. Atlanta G. Cook
    20. Frank Tüttelmann
    21. Dónal O'Carroll
  • Deleterious genetic changes in AGTPBP1 result in teratozoospermia with sperm head and flagella defects

    Journal of cellular and molecular medicine
    1. Yu Hua Lin
    2. Ya Yun Wang
    3. Tsung Hsuan Lai
    4. Jih Lung Teng
    5. Chi Wei Lin
    6. Chih Chun Ke
    7. I. Shing Yu
    8. Hui Ling Lee
    9. Chying Chyuan Chan
    10. Chi Hua Tung
    11. Donald F. Conrad
    12. Moira K. O'Bryan
    13. Ying Hung Lin
  • Genetic mutation of Cep76 results in male infertility due to abnormal sperm tail composition

    Life science alliance
    1. Brendan J. Houston
    2. D. Jo Merriner
    3. G. Gemma Stathatos
    4. Joseph H. Nguyen
    5. Anne E. O’connor
    6. Alexandra M. Lopes
    7. Donald F. Conrad
    8. Mark Baker
    9. Jessica E.M. Dunleavy
    10. Moira K. O’bryan
  • Heterozygous loss-of-function SMC3 variants are associated with variable growth and developmental features

    Human Genetics and Genomics Advances
    1. Morad Ansari
    2. Kamli N.W. Faour
    3. Akiko Shimamura
    4. Graeme Grimes
    5. Emeline M. Kao
    6. Erica R. Denhoff
    7. Ana Blatnik
    8. Daniel Ben-Isvy
    9. Lily Wang
    10. Benjamin M. Helm
    11. Helen Firth
    12. Amy M. Breman
    13. Emilia K. Bijlsma
    14. Aiko Iwata-Otsubo
    15. Thomy J.L. de Ravel
    16. Vincent Fusaro
    17. Alan Fryer
    18. Keith Nykamp
    19. Lara G. Stühn
    20. Tobias B. Haack
    21. G. Christoph Korenke
    22. Panayiotis Constantinou
    23. Kinga M. Bujakowska
    24. Karen J. Low
    25. Emily Place
    26. Jennifer Humberson
    27. Melanie P. Napier
    28. Jessica Hoffman
    29. Jane Juusola
    30. Matthew A. Deardorff
    31. Wanqing Shao
    32. Shira Rockowitz
    33. Ian Krantz
    34. Maninder Kaur
    35. Sarah Raible
    36. Victoria Dortenzio
    37. Sabine Kliesch
    38. Moriel Singer-Berk
    39. Emily Groopman
    40. Stephanie DiTroia
    41. Sonia Ballal
    42. Siddharth Srivastava
    43. Kathrin Rothfelder
    44. Saskia Biskup
    45. Jessica Rzasa
    46. Jennifer Kerkhof
    47. Haley McConkey
    48. Bekim Sadikovic
    49. Sarah Hilton
    50. Siddharth Banka
    51. Frank Tüttelmann
    52. Donald F. Conrad
    53. Anne O'Donnell-Luria
    54. Michael E. Talkowski
    55. David R. FitzPatrick
    56. Philip M. Boone
  • Inherited defects of piRNA biogenesis cause transposon de-repression, impaired spermatogenesis, and human male infertility

    Nature communications
    1. Birgit Stallmeyer
    2. Clara Bühlmann
    3. Rytis Stakaitis
    4. Ann Kristin Dicke
    5. Farah Ghieh
    6. Luisa Meier
    7. Ansgar Zoch
    8. David MacKenzie MacLeod
    9. Johanna Steingröver
    10. Özlem Okutman
    11. Daniela Fietz
    12. Adrian Pilatz
    13. Antoni Riera-Escamilla
    14. Miguel J. Xavier
    15. Christian Ruckert
    16. Sara Di Persio
    17. Nina Neuhaus
    18. Ali Sami Gurbuz
    19. Ahmet Şalvarci
    20. Nicolas Le May
    21. Kevin McEleny
    22. Corinna Friedrich
    23. Godfried van der Heijden
    24. Margot J. Wyrwoll
    25. Sabine Kliesch
    26. Joris A. Veltman
    27. Csilla Krausz
    28. Stéphane Viville
    29. Donald F. Conrad
    30. Dónal O’Carroll
    31. Frank Tüttelmann
  • The human infertility single-cell testis atlas (HISTA)

    Andrology
    1. Eisa Mahyari
    2. Katinka A. Vigh-Conrad
    3. Clément Daube
    4. Ana C. Lima
    5. Jingtao Guo
    6. Douglas T. Carrell
    7. James M. Hotaling
    8. Kenneth I. Aston
    9. Donald F. Conrad
  • Toward clinical exomes in diagnostics and management of male infertility

    American Journal of Human Genetics
    1. Kristiina Lillepea
    2. Anna Grete Juchnewitsch
    3. Laura Kasak
    4. Anu Valkna
    5. Avirup Dutta
    6. Kristjan Pomm
    7. Olev Poolamets
    8. Liina Nagirnaja
    9. Erik Tamp
    10. Eisa Mahyari
    11. Vladimir Vihljajev
    12. Stanislav Tjagur
    13. Sofia Papadimitriou
    14. Antoni Riera-Escamilla
    15. Nassim Versbraegen
    16. Ginevra Farnetani
    17. Helen Castillo-Madeen
    18. Mailis Sütt
    19. Viljo Kübarsepp
    20. Sven Tennisberg
    21. Paul Korrovits
    22. Csilla Krausz
    23. Kenneth I. Aston
    24. Tom Lenaerts
    25. Donald F. Conrad
    26. Margus Punab
    27. Maris Laan
  • Undiagnosed RASopathies in infertile men

    Frontiers in Endocrinology
    1. Anna Grete Juchnewitsch
    2. Kristjan Pomm
    3. Avirup Dutta
    4. Erik Tamp
    5. Anu Valkna
    6. Kristiina Lillepea
    7. Eisa Mahyari
    8. Stanislav Tjagur
    9. Galina Belova
    10. Viljo Kübarsepp
    11. Helen Castillo-Madeen
    12. Antoni Riera-Escamilla
    13. Lisanna Põlluaas
    14. Liina Nagirnaja
    15. Olev Poolamets
    16. Vladimir Vihljajev
    17. Mailis Sütt
    18. Nassim Versbraegen
    19. Sofia Papadimitriou
    20. Robert I. McLachlan
    21. Keith A. Jarvi
    22. Peter N. Schlegel
    23. Sven Tennisberg
    24. Paul Korrovits
    25. Katinka Vigh-Conrad
    26. Moira K. O’Bryan
    27. Kenneth I. Aston
    28. Tom Lenaerts
    29. Donald F. Conrad
    30. Laura Kasak
    31. Margus Punab
    32. Maris Laan
  • A naturally occurring variant of MBD4 causes maternal germline hypermutation in primates

    Genome Research
    1. Alexandra M. Stendahl
    2. Rashesh Sanghvi
    3. Samuel Peterson
    4. Karina Ray
    5. Ana C. Lima
    6. Raheleh Rahbari
    7. Donald F. Conrad
  • Consensus label propagation with graph convolutional networks for single-cell RNA sequencing cell type annotation

    Bioinformatics
    1. Daniel P. Lewinsohn
    2. Katinka A. Vigh-Conrad
    3. Donald F. Conrad
    4. Cory B. Scott
  • DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia

    Communications Biology
    1. Ann Kristin Dicke
    2. Adrian Pilatz
    3. Margot J. Wyrwoll
    4. Margus Punab
    5. Christian Ruckert
    6. Liina Nagirnaja
    7. Kenneth I. Aston
    8. Donald F. Conrad
    9. Sara Di Persio
    10. Nina Neuhaus
    11. Daniela Fietz
    12. Maris Laan
    13. Birgit Stallmeyer
    14. Frank Tüttelmann
  • Genome sequencing of Pakistani families with male infertility identifies deleterious genotypes in SPAG6, CCDC9, TKTL1, TUBA3C, and M1AP

    Andrology
    1. Muhammad Riaz Khan
    2. Arvand Akbari
    3. Thomas J. Nicholas
    4. Helen Castillo-Madeen
    5. Muhammad Ajmal
    6. Taqweem Ul Haq
    7. Maris Laan
    8. Aaron R. Quinlan
    9. Jasvinder S. Ahuja
    10. Aftab Ali Shah
    11. Donald F. Conrad
  • Genomic study of TEX15 variants

    Frontiers in Genetics
    1. Sidra Qureshi
    2. Jimmaline J. Hardy
    3. Christopher Pombar
    4. Andrea J. Berman
    5. Agnieszka Malcher
    6. Tara Gingrich
    7. Rachel Hvasta
    8. Jannah Kuong
    9. Sarah Munyoki
    10. Kathleen Hwang
    11. Kyle E. Orwig
    12. Jawad Ahmed
    13. Marta Olszewska
    14. Maciej Kurpisz
    15. Donald F. Conrad
    16. Muhammad Jaseem Khan
    17. Alexander N. Yatsenko
  • In vivo versus in silico assessment of potentially pathogenic missense variants in human reproductive genes

    Proceedings of the National Academy of Sciences of the United States of America
    1. Xinbao Ding
    2. Priti Singh
    3. Kerry Schimenti
    4. Tina N. Tran
    5. Robert Fragoza
    6. Jimmaline Hardy
    7. Kyle E. Orwig
    8. Marta Olszewska
    9. Maciej K. Kurpisz
    10. Alexander N. Yatsenko
    11. Donald F. Conrad
    12. Haiyuan Yu
    13. John C. Schimenti
  • Rhesus macaque fetal and placental growth demographics

    American Journal of Primatology
    1. Victoria H.J. Roberts
    2. Jenna N. Castro
    3. Brady M. Wessel
    4. Donald F. Conrad
    5. Anne D. Lewis
    6. Jamie O. Lo
  • TAD evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function

    Nature communications
    1. Mariam Okhovat
    2. Jake VanCampen
    3. Kimberly A. Nevonen
    4. Lana Harshman
    5. Weiyu Li
    6. Cora E. Layman
    7. Samantha Ward
    8. Jarod Herrera
    9. Jackson Wells
    10. Rory R. Sheng
    11. Yafei Mao
    12. Blaise Ndjamen
    13. Ana C. Lima
    14. Katinka A. Vigh-Conrad
    15. Alexandra M. Stendahl
    16. Ran Yang
    17. Lev Fedorov
    18. Ian R. Matthews
    19. Sarah A. Easow
    20. Dylan K. Chan
    21. Taha A. Jan
    22. Evan E. Eichler
    23. Sandra Rugonyi
    24. Donald F. Conrad
    25. Nadav Ahituv
    26. Lucia Carbone
  • The origins and functional effects of postzygotic mutations throughout the human life span

    Science
    1. Nicole B. Rockweiler
    2. Avinash Ramu
    3. Liina Nagirnaja
    4. Wing H. Wong
    5. Michiel J. Noordam
    6. Casey W. Drubin
    7. Ni Huang
    8. Brian Miller
    9. Ellen Z. Todres
    10. Katinka A. Vigh-Conrad
    11. Antonino Zito
    12. Kerrin S. Small
    13. Kristin G. Ardlie
    14. Barak A. Cohen
    15. Donald F. Conrad
  • Actionable secondary findings following exome sequencing of 836 non-obstructive azoospermia cases and their value in patient management

    Human Reproduction
    1. Laura Kasak
    2. Kristiina Lillepea
    3. Liina Nagirnaja
    4. Kenneth I. Aston
    5. Peter N. Schlegel
    6. João Gonçalves
    7. Filipa Carvalho
    8. Daniel Moreno-Mendoza
    9. Kristian Almstrup
    10. Michael L. Eisenberg
    11. Keith A. Jarvi
    12. Moira K. O'Bryan
    13. Alexandra M. Lopes
    14. Donald F. Conrad
    15. Margus Punab
    16. Maris Laan
  • A de novo paradigm for male infertility

    Nature communications
    1. M. S. Oud
    2. R. M. Smits
    3. H. E. Smith
    4. F. K. Mastrorosa
    5. G. S. Holt
    6. B. J. Houston
    7. P. F. de Vries
    8. B. K.S. Alobaidi
    9. L. E. Batty
    10. H. Ismail
    11. J. Greenwood
    12. H. Sheth
    13. A. Mikulasova
    14. G. D.N. Astuti
    15. C. Gilissen
    16. K. McEleny
    17. H. Turner
    18. J. Coxhead
    19. S. Cockell
    20. D. D.M. Braat
    21. K. Fleischer
    22. K. W.M. D’Hauwers
    23. E. Schaafsma
    24. Donald F. Conrad
    25. Liina Nagirnaja
    26. Kenneth I. Aston
    27. Douglas T. Carrell
    28. James M. Hotaling
    29. Timothy G. Jenkins
    30. Rob McLachlan
    31. Moira K. O’Bryan
    32. Peter N. Schlegel
    33. Michael L. Eisenberg
    34. Jay I. Sandlow
    35. Emily S. Jungheim
    36. Kenan R. Omurtag
    37. Alexandra M. Lopes
    38. Susana Seixas
    39. Filipa Carvalho
    40. Susana Fernandes
    41. Alberto Barros
    42. João Gonçalves
    43. Iris Caetano
    44. Graça Pinto
    45. Sónia Correia
    46. Maris Laan
    47. Margus Punab
    48. Ewa Rajpert De Meyts
    49. Niels Jørgensen
    50. D. F. Conrad
  • DDB1- and CUL4-associated factor 12-like protein 1 (Dcaf12l1) is not essential for male fertility in mice

    Developmental Biology
    1. Brendan J. Houston
    2. Alexandra M. Lopes
    3. Maris Laan
    4. Liina Nagirnaja
    5. Anne E. O'Connor
    6. D. Jo Merriner
    7. Joseph Nguyen
    8. Margus Punab
    9. Antoni Riera-Escamilla
    10. Csilla Krausz
    11. Kenneth Ivan Aston
    12. Donald F. Conrad
    13. Moira K. O'Bryan
  • Diverse monogenic subforms of human spermatogenic failure

    Nature communications
    1. Liina Nagirnaja
    2. Alexandra M. Lopes
    3. Wu Lin Charng
    4. Brian Miller
    5. Rytis Stakaitis
    6. Ieva Golubickaite
    7. Alexandra Stendahl
    8. Tianpengcheng Luan
    9. Corinna Friedrich
    10. Eisa Mahyari
    11. Eloise Fadial
    12. Laura Kasak
    13. Katinka Vigh-Conrad
    14. Manon S. Oud
    15. Miguel J. Xavier
    16. Samuel R. Cheers
    17. Emma R. James
    18. Jingtao Guo
    19. Timothy G. Jenkins
    20. Antoni Riera-Escamilla
    21. Alberto Barros
    22. Filipa Carvalho
    23. Susana Fernandes
    24. João Gonçalves
    25. Christina A. Gurnett
    26. Niels Jørgensen
    27. Davor Jezek
    28. Emily S. Jungheim
    29. Sabine Kliesch
    30. Robert I. McLachlan
    31. Kenan R. Omurtag
    32. Adrian Pilatz
    33. Jay I. Sandlow
    34. James Smith
    35. Michael L. Eisenberg
    36. James M. Hotaling
    37. Keith A. Jarvi
    38. Margus Punab
    39. Ewa Rajpert-De Meyts
    40. Douglas T. Carrell
    41. Csilla Krausz
    42. Maris Laan
    43. Moira K. O’Bryan
    44. Peter N. Schlegel
    45. Frank Tüttelmann
    46. Joris A. Veltman
    47. Kristian Almstrup
    48. Kenneth I. Aston
    49. Donald F. Conrad
  • Human INHBB Gene Variant (c.1079T>C:p.Met360Thr) Alters Testis Germ Cell Content, but Does Not Impact Fertility in Mice

    Endocrinology
    1. Brendan J. Houston
    2. Anne E. O'Connor
    3. Degang Wang
    4. Georgia Goodchild
    5. D. Jo Merriner
    6. Haitong Luan
    7. Don F. Conrad
    8. Liina Nagirnaja
    9. Kenneth I. Aston
    10. Sabine Kliesch
    11. Margot J. Wyrwoll
    12. Corinna Friedrich
    13. Frank Tuttelmann
    14. Craig Harrison
    15. Moira K. Obryan
    16. Kelly Walton
  • Large-scale analyses of the X chromosome in 2,354 infertile men discover recurrently affected genes associated with spermatogenic failure

    American Journal of Human Genetics
    1. Antoni Riera-Escamilla
    2. Matthias Vockel
    3. Liina Nagirnaja
    4. Miguel J. Xavier
    5. Albert Carbonell
    6. Daniel Moreno-Mendoza
    7. Marc Pybus
    8. Ginevra Farnetani
    9. Viktoria Rosta
    10. Francesca Cioppi
    11. Corinna Friedrich
    12. Manon S. Oud
    13. Godfried W. van der Heijden
    14. Armin Soave
    15. Thorsten Diemer
    16. Elisabet Ars
    17. Josvany Sánchez-Curbelo
    18. Sabine Kliesch
    19. Moira K. O'Bryan
    20. Eduard Ruiz-Castañe
    21. Fernando Azorín
    22. Joris A. Veltman
    23. Kenneth I. Aston
    24. Donald F. Conrad
    25. Frank Tüttelmann
    26. Csilla Krausz
  • SATINN

    Bioinformatics
    1. Ran Yang
    2. Alexandra M. Stendahl
    3. Katinka A. Vigh-Conrad
    4. Madison Held
    5. Ana C. Lima
    6. Donald F. Conrad