Publications

• Extended exposure to low doses of azacitidine induces differentiation of leukemic stem cells through activation of myeloperoxidase

  Haematologica Apr 2024
  1. Danny V. Jeyaraju
  2. Maryam Alapa
  3. Ann Polonskaia
  4. Alberto Risueño
  5. Prakash Subramanyam
  6. Amit Anand
  7. Kaushik Ghosh
  8. Charalampos Kyriakopoulos
  9. Daiane Hemerich
  10. Rose Hurren
  11. Xiaoming Wang
  12. Marcela Gronda
  13. Aarif Ahsan
  14. Hsiling Chiu
  15. Geethu Thomas
  16. Evan F. Lind
  17. Daniel L. Menezes
  18. Aaron D. Schimmer
  19. Patrick R. Hagner
  20. Anita Gandhi
  21. Anjan G. Thakurta

• Leukemic mutation FLT3-ITD is retained in dendritic cells and disrupts their homeostasis leading to expanded Th17 frequency

  Frontiers in immunology 2024
  1. Patrick A. Flynn
  2. Mark D. Long
  3. Yoko Kosaka
  4. Nicola Long
  5. Jessica S. Mulkey
  6. Jesse L. Coy
  7. Anupriya Agarwal
  8. Evan F. Lind

• BET inhibitors rescue anti-PD1 resistance by enhancing TCF7 accessibility in leukemia-derived terminally exhausted CD8⁺ T cells

  Leukemia 2023
  1. Kyle A. Romine
  2. Kevin MacPherson
  3. Hyun jun Cho
  4. Yoko Kosaka
  5. Patrick A. Flynn
  6. Kaelan H. Byrd
  7. Jesse L. Coy
  8. Matthew T. Newman
  9. Ravina Pandita
  10. Christopher P. Loo
  11. Jaime Scott
  12. Andrew C. Adey
  13. Evan F. Lind

• Patient-Specific Targeting of the T-Cell Receptor Variable Region as a Therapeutic Strategy in Clonal T-Cell Diseases

  Clinical Cancer Research Oct 15, 2023
  1. Olivia M. Lucero
  2. Ji Ann Lee
  3. Jenna Bowman
  4. Kara Johnson
  5. Gopal Sapparapu
  6. John K. Thomas
  7. Guang Fan
  8. Bill H. Chang
  9. Karina Thiel-Klare
  10. Christopher A. Eide
  11. Craig Okada
  12. Mike Palazzolo
  13. Evan Lind
  14. Yoko Kosaka
  15. Brian J. Druker
  16. Nicholas Lydon
  17. Peter M. Bowers

• Integrative analysis of drug response and clinical outcome in acute myeloid leukemia

  Cancer Cell Aug 8, 2022
  1. Daniel Bottomly
  2. Nicola Long
  3. Anna Reister Schultz
  4. Stephen E. Kurtz
  5. Cristina E. Tognon
  6. Kara Johnson
  7. Melissa Abel
  8. Anupriya Agarwal
  9. Sammantha Avaylon
  10. Erik Benton
  11. Aurora Blucher
  12. Uma Borate
  13. Theodore P. Braun
  14. Jordana Brown
  15. Jade Bryant
  16. Russell Burke
  17. Amy Carlos
  18. Bill H. Chang
  19. Hyun Jun Cho
  20. Stephen Christy
  21. Cody Coblentz
  22. Aaron M. Cohen
  23. Amanda d'Almeida
  24. Rachel Cook
  25. Alexey Danilov
  26. Kim Hien T. Dao
  27. Michie Degnin
  28. James Dibb
  29. Christopher A. Eide
  30. Isabel English
  31. Stuart Hagler
  32. Heath Harrelson
  33. Rachel Henson
  34. Hibery Ho
  35. Sunil K. Joshi
  36. Brian Junio
  37. Andy Kaempf
  38. Yoko Kosaka
  39. Ted Laderas
  40. Matt Lawhead
  41. Hyunjung Lee
  42. Jessica T. Leonard
  43. Chenwei Lin
  44. Evan F. Lind
  45. Selina Qiuying Liu
  46. Pierrette Lo
  47. Marc M. Loriaux
  48. Samuel Luty
  49. Julia E. Maxson
  50. Tara Macey
  51. Jacqueline Martinez
  52. Jessica Minnier
  53. Andrea Monteblanco
  54. Motomi Mori
  55. Quinlan Morrow
  56. Dylan Nelson
  57. Justin Ramsdill
  58. Angela Rofelty
  59. Alexandra Rogers
  60. Kyle A. Romine
  61. Peter Ryabinin
  62. Jennifer N. Saultz
  63. David A. Sampson
  64. Samantha L. Savage
  65. Robert Schuff
  66. Robert Searles
  67. Rebecca L. Smith
  68. Stephen E. Spurgeon
  69. Tyler Sweeney
  70. Ronan T. Swords
  71. Aashis Thapa
  72. Karina Thiel-Klare
  73. Elie Traer
  74. Jake Wagner
  75. Beth Wilmot
  76. Joelle Wolf
  77. Guanming Wu
  78. Amy Yates
  79. Haijiao Zhang
  80. Christopher R. Cogle
  81. Robert H. Collins
  82. Michael W. Deininger
  83. Christopher S. Hourigan
  84. Craig T. Jordan
  85. Tara L. Lin
  86. Micaela E. Martinez
  87. Rachel R. Pallapati
  88. Daniel A. Pollyea
  89. Anthony D. Pomicter
  90. Justin M. Watts
  91. Scott J. Weir
  92. Brian J. Druker
  93. Shannon K. McWeeney
  94. Jeffrey W. Tyner

• Concomitant use of a dual Src/ABL kinase inhibitor eliminates the in vitro efficacy of blinatumomab against Ph⁺ ALL

  Blood Feb 18, 2021
  1. Jessica T. Leonard
  2. Yoko Kosaka
  3. Pavani Malla
  4. Dorian LaTocha
  5. Adam Lamble
  6. Brandon Hayes-Lattin
  7. Kaelan Byrd
  8. Brian J. Druker
  9. Jeffrey W. Tyner
  10. Bill H. Chang
  11. Evan Lind

• Immunomodulatory effects of pevonedistat, a NEDD8-activating enzyme inhibitor, in chronic lymphocytic leukemia-derived T cells

  Leukemia Jan 1, 2020
  1. Scott Best
  2. Vi Lam
  3. Tingting Liu
  4. Nur Bruss
  5. Adam Kittai
  6. Olga V. Danilova
  7. Susan Murray
  8. Allison Berger
  9. Nathan D. Pennock
  10. Evan F. Lind
  11. Alexey V. Danilov

• Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia

  Proceedings of the National Academy of Sciences of the United States of America Jun 23, 2020
  1. Adam J. Lamble
  2. Yoko Kosaka
  3. Ted Laderas
  4. Allie Maffit
  5. Andy Kaempf
  6. Lauren K. Brady
  7. Weiwei Wang
  8. Nicola Long
  9. Jennifer N. Saultz
  10. Motomi Mori
  11. David Soong
  12. Clare V. LeFave
  13. Fei Huang
  14. Homer Adams
  15. Marc M. Loriaux
  16. Cristina E. Tognon
  17. Pierrette Lo
  18. Jeffrey W. Tyner
  19. Guang Fan
  20. Shannon K. McWeeney
  21. Brian J. Druker
  22. Evan F. Lind

• Acute myeloid leukemia–induced T-cell suppression can be reversed by inhibition of the MAPK pathway

  Blood Advances Oct 22, 2019
  1. Kaycee B. Moshofsky
  2. Hyun J. Cho
  3. Guanming Wu
  4. Kyle A. Romine
  5. Matthew T. Newman
  6. Yoko Kosaka
  7. Shannon K. McWeeney
  8. Evan F. Lind

• Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

  Nature communications Dec 1, 2019
  1. Haijiao Zhang
  2. Samantha Savage
  3. Anna Reister Schultz
  4. Daniel Bottomly
  5. Libbey White
  6. Erik Segerdell
  7. Beth Wilmot
  8. Shannon K. McWeeney
  9. Christopher A. Eide
  10. Tamilla Nechiporuk
  11. Amy Carlos
  12. Rachel Henson
  13. Chenwei Lin
  14. Robert Searles
  15. Hoang Ho
  16. Yee Ling Lam
  17. Richard Sweat
  18. Courtney Follit
  19. Vinay Jain
  20. Evan Lind
  21. Gautam Borthakur
  22. Guillermo Garcia-Manero
  23. Farhad Ravandi
  24. Hagop M. Kantarjian
  25. Jorge Cortes
  26. Robert Collins
  27. Daelynn R. Buelow
  28. Sharyn D. Baker
  29. Brian J. Druker
  30. Jeffrey W. Tyner

• CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells

  Blood Feb 7, 2019
  1. David K. Edwards
  2. Kevin Watanabe-Smith
  3. Angela Rofelty
  4. Alisa Damnernsawad
  5. Ted Laderas
  6. Adam Lamble
  7. Evan F. Lind
  8. Andy Kaempf
  9. Motomi (Tomi) Mori
  10. Mara Rosenberg
  11. Amanda d’Almeida
  12. Nicola Long
  13. Anupriya Agarwal
  14. David Tyler Sweeney
  15. Marc Loriaux
  16. Shannon K. McWeeney
  17. Jeffrey W. Tyner

• Integrated functional and mass spectrometry-based flow cytometric phenotyping to describe the immune microenvironment in acute myeloid leukemia

  Journal of Immunological Methods Jan 1, 2017
  1. Adam J. Lamble
  2. Matthew Dietz
  3. Ted Laderas
  4. Shannon McWeeney
  5. Evan F. Lind

• Timed Regulation of 3BP2 Induction Is Critical for Sustaining CD8⁺ T Cell Expansion and Differentiation

  Cell Reports Jul 31, 2018
  1. Ioannis D. Dimitriou
  2. Korris Lee
  3. Itoro Akpan
  4. Evan F. Lind
  5. Valarie A. Barr
  6. Pamela S. Ohashi
  7. Lawrence E. Samelson
  8. Robert Rottapel

• Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2

  Cancer Cell Oct 30, 2015
  1. Satoshi Inoue
  2. Wanda Y. Li
  3. Alan Tseng
  4. Isabel Beerman
  5. Andrew J. Elia
  6. Sean C. Bendall
  7. François Lemonnier
  8. Ken J. Kron
  9. David W. Cescon
  10. Zhenyue Hao
  11. Evan F. Lind
  12. Naoya Takayama
  13. Aline C. Planello
  14. Shu Yi Shen
  15. Alan H. Shih
  16. Dana M. Larsen
  17. Qinxi Li
  18. Bryan E. Snow
  19. Andrew Wakeham
  20. Jillian Haight
  21. Chiara Gorrini
  22. Christian Bassi
  23. Kelsie L. Thu
  24. Kiichi Murakami
  25. Alisha R. Elford
  26. Takeshi Ueda
  27. Kimberly Straley
  28. Katharine E. Yen
  29. Gerry Melino
  30. Luisa Cimmino
  31. Iannis Aifantis
  32. Ross L. Levine
  33. Daniel D. De Carvalho
  34. Mathieu Lupien
  35. Derrick J. Rossi
  36. Garry P. Nolan
  37. Rob A. Cairns
  38. Tak W. Mak

• Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP +/NADPH ratio

  Cell Death and Differentiation Nov 1, 2015
  1. M. Itsumi
  2. S. Inoue
  3. A. J. Elia
  4. K. Murakami
  5. M. Sasaki
  6. E. F. Lind
  7. D. Brenner
  8. I. S. Harris
  9. I. I.C. Chio
  10. S. Afzal
  11. R. A. Cairns
  12. D. W. Cescon
  13. A. R. Elford
  14. J. Ye
  15. P. A. Lang
  16. W. Y. Li
  17. A. Wakeham
  18. G. S. Duncan
  19. J. Haight
  20. A. You-Ten
  21. B. Snow
  22. K. Yamamoto
  23. P. S. Ohashi
  24. T. W. Mak

• MiR-155 upregulation in dendritic cells is sufficient to break tolerance in vivo by negatively regulating SHIP1

  Journal of Immunology Nov 15, 2015
  1. Evan F. Lind
  2. Douglas G. Millar
  3. Dilan Dissanayake
  4. Jonathan C. Savage
  5. Natasha K. Grimshaw
  6. William G. Kerr
  7. Pamela S. Ohashi

• Mir-155, a central modulator of T-cell responses

  European Journal of Immunology Jan 2014
  1. Evan F. Lind
  2. Pamela S. Ohashi

• Micro-RNA 155 Is required for Optimal CD₈+ T Cell responses to acute viral and intracellular bacterial challenges

  Journal of Immunology Feb 1, 2013
  1. Evan F. Lind
  2. Alisha R. Elford
  3. Pamela S. Ohashi

• Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cells

  PloS one Apr 18, 2012
  1. Samit Chatterjee
  2. Laurie Seifried
  3. Michael E. Feigin
  4. Don L. Gibbons
  5. Claudio Scuoppo
  6. Wei Lin
  7. Zain H. Rizvi
  8. Evan Lind
  9. Dilan Dissanayake
  10. Jonathan Kurie
  11. Pam Ohashi
  12. Senthil K. Muthuswamy

• IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

  Nature Aug 30, 2012
  1. Masato Sasaki
  2. Christiane B. Knobbe
  3. Joshua C. Munger
  4. Evan F. Lind
  5. Dirk Brenner
  6. Anne Brüstle
  7. Isaac S. Harris
  8. Roxanne Holmes
  9. Andrew Wakeham
  10. Jillian Haight
  11. Annick You-Ten
  12. Wanda Y. Li
  13. Stefanie Schalm
  14. Shinsan M. Su
  15. Carl Virtanen
  16. Guido Reifenberger
  17. Pamela S. Ohashi
  18. Dwayne L. Barber
  19. Maria E. Figueroa
  20. Ari Melnick
  21. Juan Carlos Zúñiga-Pflücker
  22. Tak W. Mak

• The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk

  Oncogene Feb 16, 2012
  1. E. Arpaia
  2. H. Blaser
  3. M. Quintela-Fandino
  4. G. Duncan
  5. H. S. Leong
  6. A. Ablack
  7. S. C. Nambiar
  8. E. F. Lind
  9. J. Silvester
  10. C. K. Fleming
  11. A. Rufini
  12. M. W. Tusche
  13. A. Brüstle
  14. P. S. Ohashi
  15. J. D. Lewis
  16. T. W. Mak

• HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1

  Proceedings of the National Academy of Sciences of the United States of America Feb 9, 2010
  1. Miguel Quintela-Fandino
  2. Enrico Arpaia
  3. Dirk Brenner
  4. Theo Goh
  5. Faith Au Yeung
  6. Heiko Blaser
  7. Roumiana Alexandrova
  8. Evan F. Lind
  9. Mike W. Tusche
  10. Andrew Wakeham
  11. Pamela S. Ohashi
  12. Tak W. Mak

• Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

  Journal of Experimental Medicine Dec 21, 2009
  1. Shintaro Kamizono
  2. Gordon S. Duncan
  3. Markus G. Seidel
  4. Akira Morimoto
  5. Koichi Hamada
  6. Gerard Grosveld
  7. Koichi Akashi
  8. Evan F. Lind
  9. Jillian P. Haight
  10. Pamela S. Ohashi
  11. A. Thomas Look
  12. Tak W. Mak

• Dendritic cells require the NF-κB2 pathway for cross-presentation of soluble antigens

  Journal of Immunology 2008
  1. Evan F. Lind
  2. Cory L. Ahonen
  3. Anna Wasiuk
  4. Yoko Kosaka
  5. Burkhard Becher
  6. Kathy A. Bennett
  7. Randolph J. Noelle

• Strategies for selective priming of memory B cells

  Immunology Letters Apr 15, 2007
  1. Vanitha S. Raman
  2. Evan F. Lind
  3. Micah J. Benson
  4. Randolph J. Noelle

• The in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation

  Blood Jul 1, 2007
  1. Li Fan Lu
  2. Cory L. Ahonen
  3. Evan F. Lind
  4. Vanitha S. Raman
  5. W. James Cook
  6. G. Li Lin
  7. Randolph J. Noelle

• Imprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor

  Journal of Immunology Dec 1, 2006
  1. Brian P. O'Connor
  2. Laura A. Vogel
  3. Weijun Zhang
  4. William Loo
  5. Danielle Shnider
  6. Evan F. Lind
  7. Michelle Ratliff
  8. Randolph J. Noelle
  9. Loren D. Erickson

• Mast cells are essential intermediaries in regulatory T-cell tolerance

  Nature Aug 31, 2006
  1. Li Fan Lu
  2. Evan F. Lind
  3. David C. Gondek
  4. Kathy A. Bennett
  5. Michael W. Gleeson
  6. Karina Pino-Lagos
  7. Zachary A. Scott
  8. Anthony J. Coyle
  9. Jennifer L. Reed
  10. Jacques Van Snick
  11. Terry B. Strom
  12. Xin Xiao Zheng
  13. Randolph J. Noelle