Publications

• Biolayer interferometry for measuring the kinetics of protein–protein interactions and nanobody binding

  Nature protocols 2024
  1. Timothy A. Bates
  2. Sintayehu K. Gurmessa
  3. Jules B. Weinstein
  4. Mila Trank-Greene
  5. Xammy Huu Wrynla
  6. Aidan Anastas
  7. Teketay Wassie Anley
  8. Audrey Hinchliff
  9. Ujwal Shinde
  10. John E. Burke
  11. Fikadu G. Tafesse

• A nanobody interaction with SARS-COV-2 Spike allows the versatile targeting of lentivirus vectors

  Journal of virology Sep 2024
  1. Ayna Alfadhli
  2. Timothy A. Bates
  3. Robin Lid Barklis
  4. Ce Ann Romanaggi
  5. Fikadu G. Tafesse
  6. Eric Barklis

• Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation

  Communications Biology Dec 2024
  1. Corinna A. Kulicke
  2. Gwendolyn M. Swarbrick
  3. Nicole A. Ladd
  4. Meghan Cansler
  5. Megan Null
  6. Aneta Worley
  7. Chance Lemon
  8. Tania Ahmed
  9. Joshua Bennett
  10. Taylor N. Lust
  11. Chelsea M. Heisler
  12. Megan E. Huber
  13. Jason R. Krawic
  14. Laurisa M. Ankley
  15. Savannah K. McBride
  16. Fikadu G. Tafesse
  17. Andrew J. Olive
  18. William H. Hildebrand
  19. Deborah A. Lewinsohn
  20. Erin J. Adams
  21. David M. Lewinsohn
  22. Melanie J. Harriff

• Diverging Maternal and Cord Antibody Functions From SARS-CoV-2 Infection and Vaccination in Pregnancy

  Journal of Infectious Diseases Feb 15, 2024
  1. Emily H. Adhikari
  2. Pei Lu
  3. Ye Jin Kang
  4. Ann R. McDonald
  5. Jessica E. Pruszynski
  6. Timothy A. Bates
  7. Savannah K. McBride
  8. Mila Trank-Greene
  9. Fikadu G. Tafesse
  10. Lenette L. Lu

• ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages

  eLife May 28, 2024
  1. Timothy A. Bates
  2. Mila Trank-Greene
  3. Xammy Nguyenla
  4. Aidan Anastas
  5. Sintayehu K. Gurmessa
  6. Ilaria R. Merutka
  7. Shandee Dixon
  8. Anthony Shumate
  9. Abigail R. Groncki
  10. Matthew A.H. Parson
  11. Jessica R. Ingram
  12. Eric Barklis
  13. John E. Burke
  14. Ujwal Shinde
  15. Hidde L. Ploegh
  16. Fikadu G. Tafesse

• Evaluating Humoral Immunity Elicited by XBB.1.5 Monovalent COVID-19 Vaccine

  Emerging infectious diseases Jun 2024
  1. Xammy Huu Nguyenla
  2. Timothy A. Bates
  3. Mila Trank-Greene
  4. Mastura Wahedi
  5. Fikadu G. Tafesse
  6. Marcel Curlin

• Trifunctional fatty acid derivatives

  Chemical Communications May 25, 2024
  1. Scotland E. Farley
  2. Ryu Hashimoto
  3. Judah Evangelista
  4. Frank Stein
  5. Per Haberkant
  6. Kazuya Kikuchi
  7. Fikadu G. Tafesse
  8. Carsten Schultz

• Trifunctional Sphinganine

  ACS chemical biology Feb 16, 2024
  1. Scotland Farley
  2. Frank Stein
  3. Per Haberkant
  4. Fikadu G. Tafesse
  5. Carsten Schultz

• An extended interval between vaccination and infection enhances hybrid immunity against SARS-CoV-2 variants

  JCI Insight Mar 8, 2023
  1. Timothy A. Bates
  2. Hans C. Leier
  3. Savannah K. McBride
  4. Devin Schoen
  5. Zoe L. Lyski
  6. David X. Lee
  7. William Messer
  8. Marcel Curlin
  9. Fikadu G. Tafesse

• A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants

  Nature communications Dec 2022
  1. Scotland E. Farley
  2. Jennifer E. Kyle
  3. Hans C. Leier
  4. Lisa M. Bramer
  5. Jules B. Weinstein
  6. Timothy A. Bates
  7. Joon Yong Lee
  8. Thomas O. Metz
  9. Carsten Schultz
  10. Fikadu G. Tafesse

• A lyophilized colorimetric RT-LAMP test kit for rapid, low-cost, at-home molecular testing of SARS-CoV-2 and other pathogens

  Scientific Reports Dec 2022
  1. Xin Song
  2. Felicity J. Coulter
  3. Ming Yang
  4. Jessica L. Smith
  5. Fikadu G. Tafesse
  6. William B. Messer
  7. John H. Reif

• A potent alpaca-derived nanobody that neutralizes SARS-CoV-2 variants

  iScience Mar 18, 2022
  1. Jules B. Weinstein
  2. Timothy A. Bates
  3. Hans C. Leier
  4. Savannah K. McBride
  5. Eric Barklis
  6. Fikadu G. Tafesse

• A Single Dose of ChAdOx1 nCoV-19 Vaccine Elicits High Antibody Responses in Individuals with Prior SARS-CoV-2 Infection Comparable to That of Two-Dose-Vaccinated, SARS-CoV-2-Infection-Naïve Individuals

  Vaccines Jun 2022
  1. Tesfaye Gelanew
  2. Andargachew Mulu
  3. Markos Abebe
  4. Timothy A. Bates
  5. Liya Wassie
  6. Mekonnen Teferi
  7. Dessalegn Fentahun
  8. Aynalem Alemu
  9. Frehiwot Tamiru
  10. Gebeyehu Assefa
  11. Abebe Genetu Bayih
  12. Fikadu G. Tafesse
  13. Adane Mihret
  14. Alemseged Abdissa

• BNT162b2-induced neutralizing and non-neutralizing antibody functions against SARS-CoV-2 diminish with age

  Cell Reports Oct 25, 2022
  1. Timothy A. Bates
  2. Pei Lu
  3. Ye Jin Kang
  4. Devin Schoen
  5. Micah Thornton
  6. Savannah K. McBride
  7. Chanhee Park
  8. Daehwan Kim
  9. William B. Messer
  10. Marcel E. Curlin
  11. Fikadu G. Tafesse
  12. Lenette L. Lu

• Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants

  Journal of Natural Products Jan 28, 2022
  1. Richard B. van Breemen
  2. Ruth N. Muchiri
  3. Timothy A. Bates
  4. Jules B. Weinstein
  5. Hans C. Leier
  6. Scotland Farley
  7. Fikadu G. Tafesse

• High seroprevalence of anti-SARS-CoV-2 antibodies among Ethiopian healthcare workers

  BMC Infectious Diseases Dec 2022
  1. Tesfaye Gelanew
  2. Berhanu Seyoum
  3. Andargachew Mulu
  4. Adane Mihret
  5. Markos Abebe
  6. Liya Wassie
  7. Baye Gelaw
  8. Abebe Sorsa
  9. Yared Merid
  10. Yilkal Muchie
  11. Zelalem Teklemariam
  12. Bezalem Tesfaye
  13. Mahlet Osman
  14. Gutema Jebessa
  15. Abay Atinafu
  16. Tsegaye Hailu
  17. Antenehe Habte
  18. Dagaga Kenea
  19. Anteneh Gadisa
  20. Desalegn Admasu
  21. Emnet Tesfaye
  22. Timothy A. Bates
  23. Jote Tafese Bulcha
  24. Rea Tschopp
  25. Dareskedar Tsehay
  26. Kim Mullholand
  27. Rawleigh Howe
  28. Abebe Genetu
  29. Fikadu G. Tafesse
  30. Alemseged Abdissa

• Omicron neutralizing antibody response following booster vaccination compared with breakthrough infection

  Med 2022
  1. Marcel E. Curlin
  2. Timothy A. Bates
  3. Gaelen Guzman
  4. Devin Schoen
  5. Savannah K. McBride
  6. Samuel D. Carpenter
  7. Fikadu G. Tafesse

• Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Specific Memory B Cells from Individuals with Diverse Disease Severities Recognize SARS-CoV-2 Variants of Concern

  Journal of Infectious Diseases Mar 15, 2022
  1. Zoe L. Lyski
  2. Amanda E. Brunton
  3. Matt I. Strnad
  4. Peter E. Sullivan
  5. Sarah A.R. Siegel
  6. Fikadu G. Tafesse
  7. Mark K. Slifka
  8. William B. Messer

• Vaccination before or after SARS-CoV-2 infection leads to robust humoral response and antibodies that effectively neutralize variants

  Science Immunology Feb 2022
  1. Timothy A. Bates
  2. Savannah K. McBride
  3. Hans C. Leier
  4. Gaelen Guzman
  5. Zoe L. Lyski
  6. Devin Schoen
  7. Bradie Winders
  8. Joon Yong Lee
  9. David Xthona Lee
  10. William B. Messer
  11. Marcel E. Curlin
  12. Fikadu G. Tafesse

• Capsid-specific nanobody effects on HIV-1 assembly and infectivity

  Virology Oct 2021
  1. Ayna Alfadhli
  2. Ce Ann Romanaggi
  3. Robin Lid Barklis
  4. Ilaria Merutka
  5. Timothy A. Bates
  6. Fikadu G. Tafesse
  7. Eric Barklis

• Ceramide synthase 2 deletion decreases the infectivity of HIV-1

  Journal of Biological Chemistry Jan 1, 2021
  1. Eric Barklis
  2. Ayna Alfadhli
  3. Jennifer E. Kyle
  4. Lisa M. Bramer
  5. Kent J. Bloodsworth
  6. Robin Lid Barklis
  7. Hans C. Leier
  8. R. Max Petty
  9. Iris D. Zelnik
  10. Thomas O. Metz
  11. Anthony H. Futerman
  12. Fikadu G. Tafesse

• Cross-reactivity of SARS-CoV structural protein antibodies against SARS-CoV-2

  Cell Reports Feb 16, 2021
  1. Timothy A. Bates
  2. Jules B. Weinstein
  3. Scotland Farley
  4. Hans C. Leier
  5. William B. Messer
  6. Fikadu G. Tafesse

• Neutralization of SARS-CoV-2 variants by convalescent and BNT162b2 vaccinated serum

  Nature communications Dec 1, 2021
  1. Timothy A. Bates
  2. Hans C. Leier
  3. Zoe L. Lyski
  4. Savannah K. McBride
  5. Felicity J. Coulter
  6. Jules B. Weinstein
  7. James R. Goodman
  8. Zhengchun Lu
  9. Sarah A.R. Siegel
  10. Peter Sullivan
  11. Matt Strnad
  12. Amanda E. Brunton
  13. David X. Lee
  14. Andrew C. Adey
  15. Benjamin N. Bimber
  16. Brian J. O’Roak
  17. Marcel E. Curlin
  18. William B. Messer
  19. Fikadu G. Tafesse

• Sphingomyelin biosynthesis is essential for phagocytic signaling during mycobacterium tuberculosis host cell entry

  mBio Jan 1, 2021
  1. Patrick Niekamp
  2. Gaelen Guzman
  3. Hans C. Leier
  4. Ali Rashidfarrokhi
  5. Veronica Richina
  6. Fabian Pott
  7. Caroline Barisch
  8. Joost C.M. Holthuis
  9. Fikadu G. Tafesse

• A global lipid map defines a network essential for Zika virus replication

  Nature communications Dec 1, 2020
  1. Hans C. Leier
  2. Jules B. Weinstein
  3. Jennifer E. Kyle
  4. Joon Yong Lee
  5. Lisa M. Bramer
  6. Kelly G. Stratton
  7. Douglas Kempthorne
  8. Aaron R. Navratil
  9. Endale G. Tafesse
  10. Thorsten Hornemann
  11. William B. Messer
  12. Edward A. Dennis
  13. Thomas O. Metz
  14. Eric Barklis
  15. Fikadu G. Tafesse

• Alternative splicing of MR1 regulates antigen presentation to MAIT cells

  Scientific Reports Dec 1, 2020
  1. Gitanjali A. Narayanan
  2. Abhinav Nellore
  3. Jessica Tran
  4. Aneta H. Worley
  5. Erin W. Meermeier
  6. Elham Karamooz
  7. Megan E. Huber
  8. Regina Kurapova
  9. Fikadu G. Tafesse
  10. Melanie J. Harriff
  11. David M. Lewinsohn