Guang Fan, M.D., Ph.D. (she/her)

  • Professor of Pathology & Laboratory Medicine, School of Medicine
  • Chair
  • Medical Director, Clinical Laboratory
  • Vice Chair, Clinical Pathology
  • Clinical Service Chief
  • Medical Director, Point of Care Testing
  • Director, Clinical Chemistry and Toxicology

Biography

Dr. Fan is an expert in diagnosis of leukemia, lymphoma, congenitial and acquired bone marrow failure disorders. 

Dr. Fan's research interest is in developing sensitive and advanced diagnotic tests for leukemia and lymphoma.

Education and training

  • Degrees

    • M.D., 1986, Beijing Medical University
    • M.S., 1989, Beijing Medical University
    • Ph.D., 1992, Wayne State University
  • Residency

    • Anatomic and Clinical Pathology, University of Cincinnati, 1996-2000
  • Fellowship

    • Hematopathology, Indiana University, 2000-2001
  • Certifications

    • Anatomic and Clinical Pathology (American Board of Pathology), 2000
    • Hematology (American Board of Pathology), 2001

Publications

Elsevier pure profile

Publications

  • Systemic ALK-negative anaplastic large cell lymphoma

    Human Pathology
    1. Wei Xie
    2. L. Jeffrey Medeiros
    3. Guang Fan
    4. Shaoying Li
    5. Jie Xu
  • Immunological dynamic characteristics in acute myeloid leukemia predict the long-term outcomes and graft-versus host-disease occurrences post-transplantation

    Clinical and Experimental Immunology
    1. Weiwei Wang
    2. Haibo Li
    3. Yukun Guo
    4. Lihua Zhang
    5. Wenli Jiang
    6. Naisheng Zheng
    7. Se Peng
    8. Xiaolin Guan
    9. Guang Fan
    10. Lisong Shen
  • Landscape of somatic mutations and clonal evolution in NUP98-rearranged adult acute myeloid leukaemia

    British Journal of Haematology
    1. Candace Frerich
    2. Peng Li
    3. Philipp W. Raess
    4. Jennifer Dunlap
    5. Curtis Lachowiez
    6. Jose Solis-Ruiz
    7. Richard Press
    8. Nicola Long
    9. Ronan T. Swords
    10. Joanna Wiszniewska
    11. Guang Fan
    12. Wei Xie
  • Performance Evaluation of a Novel Artificial Intelligence–Assisted Digital Microscopy System for the Routine Analysis of Bone Marrow Aspirates

    Modern Pathology
    1. Adam Bagg
    2. Philipp W. Raess
    3. Deborah Rund
    4. Siddharth Bhattacharyya
    5. Joanna Wiszniewska
    6. Alon Horowitz
    7. Darrin Jengehino
    8. Guang Fan
    9. Michelle Huynh
    10. Abdoulaye Sanogo
    11. Irit Avivi
    12. Ben Zion Katz
  • Validation of Artificial Intelligence (AI)-Assisted Flow Cytometry Analysis for Immunological Disorders

    Diagnostics
    1. Zhengchun Lu
    2. Mayu Morita
    3. Tyler S. Yeager
    4. Yunpeng Lyu
    5. Sophia Y. Wang
    6. Zhigang Wang
    7. Guang Fan
  • Cytogenetically Cryptic Acute Promyelocytic Leukemia

    International journal of molecular sciences
    1. Maedeh Mohebnasab
    2. Peng Li
    3. Bo Hong
    4. Jennifer Dunlap
    5. Elie Traer
    6. Guang Fan
    7. Richard D. Press
    8. Stephen R. Moore
    9. Wei Xie
  • Evolution of SARS-CoV-2 Viral Mutations in Individuals with Prolonged Infections

    Annals of Clinical and Laboratory Science
    1. Luna Jiang-Qin
    2. Kevin Weitemier
    3. Guang Fan
    4. Xuan Qin
  • Patient-Specific Targeting of the T-Cell Receptor Variable Region as a Therapeutic Strategy in Clonal T-Cell Diseases

    Clinical Cancer Research
    1. Olivia M. Lucero
    2. Ji Ann Lee
    3. Jenna Bowman
    4. Kara Johnson
    5. Gopal Sapparapu
    6. John K. Thomas
    7. Guang Fan
    8. Bill H. Chang
    9. Karina Thiel-Klare
    10. Christopher A. Eide
    11. Craig Okada
    12. Mike Palazzolo
    13. Evan Lind
    14. Yoko Kosaka
    15. Brian J. Druker
    16. Nicholas Lydon
    17. Peter M. Bowers
  • Adult acute myeloid leukemia patients with NUP98 rearrangement have frequent cryptic translocations and unfavorable outcome

    Leukemia and Lymphoma
    1. Wei Xie
    2. Philipp W. Raess
    3. Jennifer Dunlap
    4. Cristina Magallanes Hoyos
    5. Hongmei Li
    6. Peng Li
    7. Ronan Swords
    8. Susan B. Olson
    9. Fei Yang
    10. Tauangtham Anekpuritanang
    11. Shimin Hu
    12. Joanna Wiszniewska
    13. Guang Fan
    14. Richard D. Press
    15. Stephen R. Moore
  • A novel heptasomy 21 associated with complete loss of heterozygosity and loss of function RUNX1 mutation in acute myeloid leukemia

    Cancer Genetics
    1. Fei Yang
    2. Yassmine Akkari
    3. Guang Fan
    4. Susan Olson
    5. Stephen Moore
  • Bimodal distribution pattern associated with the PCR cycle threshold (Ct) and implications in COVID-19 infections

    Scientific Reports
    1. Doris Yang
    2. Donna E. Hansel
    3. Marcel E. Curlin
    4. John M. Townes
    5. William B. Messer
    6. Guang Fan
    7. Xuan Qin
  • Community-Based SARS-CoV-2 Testing Using Saliva or Nasopharyngeal Swabs to Compare the Performance of Weekly COVID-19 Screening to Wastewater SARS-CoV-2 Signals

    ACS ES and T Water
    1. Zhengchun Lu
    2. Amanda E. Brunton
    3. Maedeh Mohebnasab
    4. Anthony Deloney
    5. Kenneth J. Williamson
    6. Blythe A. Layton
    7. Scott Mansell
    8. Alice Brawley-Chesworth
    9. Peter Abrams
    10. Kimberly A. Wilcox
    11. F. Abron Franklin
    12. Shannon K. McWeeney
    13. Daniel N. Streblow
    14. Guang Fan
    15. Donna E. Hansel
  • Histopathological and molecular findings in a patient with Ras-associated autoimmune leukoproliferative disorder

    Human Pathology Reports
    1. Wei Xie
    2. Guang Fan
    3. Joanna Wiszniewska
    4. Richard D. Press
    5. Fei Yang
  • Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML

    Blood
    1. Fei Yang
    2. Nicola Long
    3. Tauangtham Anekpuritanang
    4. Daniel Bottomly
    5. Jonathan C. Savage
    6. Tiffany Lee
    7. Jose Solis-Ruiz
    8. Uma Borate
    9. Beth Wilmot
    10. Cristina Tognon
    11. Allison M. Bock
    12. Daniel A. Pollyea
    13. Saikripa Radhakrishnan
    14. Srinidhi Radhakrishnan
    15. Prapti Patel
    16. Robert H. Collins
    17. Srinivas Tantravahi
    18. Michael W. Deininger
    19. Guang Fan
    20. Brian Druker
    21. Ujwal Shinde
    22. Jeffrey W. Tyner
    23. Richard Press
    24. Shannon McWeeney
    25. Anupriya Agarwal
  • PD-1/PD-L1 Pathway

    Biomedicines
    1. Wei Xie
    2. L. Jeffrey Medeiros
    3. Shaoying Li
    4. Guilin Tang
    5. Guang Fan
    6. Jie Xu
  • T-cell Dysfunction upon Expression of MYC with Altered Phosphorylation at Threonine 58 and Serine 62

    Molecular Cancer Research
    1. Colin J. Daniel
    2. Carl Pelz
    3. Xiaoyan Wang
    4. Michael W. Munks
    5. Aaron Ko
    6. Dhaarini Murugan
    7. Sarah A. Byers
    8. Eleonora Juarez
    9. Karyn L. Taylor
    10. Guang Fan
    11. Lisa M. Coussens
    12. Jason M. Link
    13. Rosalie C. Sears
  • A novel somatic PLCG2 variant associated with resistance to BTK and SYK inhibition in chronic lymphocytic leukemia

    European Journal of Haematology
    1. Vikram Raghunathan
    2. Guang Fan
    3. Adam S. Kittai
    4. Craig Okada
    5. Alexey V. Danilov
    6. Stephen E. Spurgeon
  • Clinical applications of monitoring immune status with 90 immune cell subsets in human whole blood by 10-color flow cytometry

    International Journal of Laboratory Hematology
    1. Weiwei Wang
    2. Haibo Li
    3. Lihua Zhang
    4. Wenli Jiang
    5. Lisong Shen
    6. Guang Fan
  • Comparison of SARS-CoV-2 PCR-Based Detection Using Saliva or Nasopharyngeal Swab Specimens in Asymptomatic Populations

    Microbiology Spectrum
    1. Guang Fan
    2. Xuan Qin
    3. Daniel N. Streblow
    4. Cristina Magallanes Hoyos
    5. Donna E. Hansel
  • Engrafted Donor-Derived Clonal Hematopoiesis after Allogenic Hematopoietic Cell Transplantation is Associated with Chronic Graft-versus-Host Disease Requiring Immunosuppressive Therapy, but no Adverse Impact on Overall Survival or Relapse

    Transplantation and Cellular Therapy
    1. Laura F. Newell
    2. Todd Williams
    3. James Liu
    4. Yun Yu
    5. Yiyi Chen
    6. Georgeann C. Booth
    7. Rebekah J. Knight
    8. Kelli R. Goslee
    9. Rachel J. Cook
    10. Jessica Leonard
    11. Gabrielle Meyers
    12. Elie Traer
    13. Richard D. Press
    14. Guang Fan
    15. Ying Wang
    16. Philipp W. Raess
    17. Richard T. Maziarz
    18. Jennifer Dunlap
  • NEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells

    Oncotarget
    1. Adam S. Kittai
    2. Olga V. Danilova
    3. Vi Lam
    4. Tingting Liu
    5. Nur Bruss
    6. Scott Best
    7. Guang Fan
    8. Alexey V. Danilov
  • Recurrent fibrin associated diffuse large B-cell lymphoma

    Human Pathology: Case Reports
    1. Mohebnasab Maedeh
    2. Tria Francisco
    3. Kim Sunny
    4. Okada Craig
    5. Davis Jessica
    6. Fan Guang
  • Molecular Discordance between Myeloid Sarcomas and Concurrent Bone Marrows Occurs in Actionable Genes and Is Associated with Worse Overall Survival

    Journal of Molecular Diagnostics
    1. Brian Werstein
    2. Jennifer Dunlap
    3. Michael J. Cascio
    4. Robert S. Ohgami
    5. Guang Fan
    6. Richard Press
    7. Philipp W. Raess
  • Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia

    Proceedings of the National Academy of Sciences of the United States of America
    1. Adam J. Lamble
    2. Yoko Kosaka
    3. Ted Laderas
    4. Allie Maffit
    5. Andy Kaempf
    6. Lauren K. Brady
    7. Weiwei Wang
    8. Nicola Long
    9. Jennifer N. Saultz
    10. Motomi Mori
    11. David Soong
    12. Clare V. LeFave
    13. Fei Huang
    14. Homer Adams
    15. Marc M. Loriaux
    16. Cristina E. Tognon
    17. Pierrette Lo
    18. Jeffrey W. Tyner
    19. Guang Fan
    20. Shannon K. McWeeney
    21. Brian J. Druker
    22. Evan F. Lind
  • Differentiation of leukemic blasts is not completely blocked in acute myeloid leukemia

    Proceedings of the National Academy of Sciences of the United States of America
    1. Anupriya Agarwal
    2. William J. Bolosky
    3. David B. Wilson
    4. Christopher A. Eide
    5. Susan B. Olson
    6. Guang Fan
    7. Brian J. Druker
  • Next-generation sequencing-defined minimal residual disease before stem cell transplantation predicts acute myeloid leukemia relapse

    American Journal of Hematology
    1. Richard D. Press
    2. Garrett Eickelberg
    3. Allison Froman
    4. Fei Yang
    5. Alex Stentz
    6. Ellen M. Flatley
    7. Guang Fan
    8. Jeong Y. Lim
    9. Gabrielle Meyers
    10. Richard T. Maziarz
    11. Rachel J. Cook