Guang Fan, M.D., Ph.D. (she/her)
- Professor of Pathology & Laboratory Medicine, School of Medicine
- Chair
- Medical Director, Clinical Laboratory
- Vice Chair, Clinical Pathology
- Clinical Service Chief
- Medical Director, Point of Care Testing
- Director, Clinical Chemistry and Toxicology
Biography
Dr. Fan is an expert in diagnosis of leukemia, lymphoma, congenitial and acquired bone marrow failure disorders.
Dr. Fan's research interest is in developing sensitive and advanced diagnotic tests for leukemia and lymphoma.
Education and training
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Degrees
- M.D., 1986, Beijing Medical University
- M.S., 1989, Beijing Medical University
- Ph.D., 1992, Wayne State University
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Residency
- Anatomic and Clinical Pathology, University of Cincinnati, 1996-2000
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Fellowship
- Hematopathology, Indiana University, 2000-2001
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Certifications
- Anatomic and Clinical Pathology (American Board of Pathology), 2000
- Hematology (American Board of Pathology), 2001
Publications
Elsevier pure profilePublications
Systemic ALK-negative anaplastic large cell lymphoma
Human PathologyImmunological dynamic characteristics in acute myeloid leukemia predict the long-term outcomes and graft-versus host-disease occurrences post-transplantation
Clinical and Experimental ImmunologyLandscape of somatic mutations and clonal evolution in NUP98-rearranged adult acute myeloid leukaemia
British Journal of HaematologyPerformance Evaluation of a Novel Artificial Intelligence–Assisted Digital Microscopy System for the Routine Analysis of Bone Marrow Aspirates
Modern PathologyValidation of Artificial Intelligence (AI)-Assisted Flow Cytometry Analysis for Immunological Disorders
DiagnosticsCytogenetically Cryptic Acute Promyelocytic Leukemia
International journal of molecular sciencesEvolution of SARS-CoV-2 Viral Mutations in Individuals with Prolonged Infections
Annals of Clinical and Laboratory SciencePatient-Specific Targeting of the T-Cell Receptor Variable Region as a Therapeutic Strategy in Clonal T-Cell Diseases
Clinical Cancer ResearchAdult acute myeloid leukemia patients with NUP98 rearrangement have frequent cryptic translocations and unfavorable outcome
Leukemia and LymphomaA novel heptasomy 21 associated with complete loss of heterozygosity and loss of function RUNX1 mutation in acute myeloid leukemia
Cancer GeneticsBimodal distribution pattern associated with the PCR cycle threshold (Ct) and implications in COVID-19 infections
Scientific ReportsCommunity-Based SARS-CoV-2 Testing Using Saliva or Nasopharyngeal Swabs to Compare the Performance of Weekly COVID-19 Screening to Wastewater SARS-CoV-2 Signals
ACS ES and T WaterHistopathological and molecular findings in a patient with Ras-associated autoimmune leukoproliferative disorder
Human Pathology ReportsIdentification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML
BloodPD-1/PD-L1 Pathway
BiomedicinesT-cell Dysfunction upon Expression of MYC with Altered Phosphorylation at Threonine 58 and Serine 62
Molecular Cancer ResearchA novel somatic PLCG2 variant associated with resistance to BTK and SYK inhibition in chronic lymphocytic leukemia
European Journal of HaematologyClinical applications of monitoring immune status with 90 immune cell subsets in human whole blood by 10-color flow cytometry
International Journal of Laboratory HematologyComparison of SARS-CoV-2 PCR-Based Detection Using Saliva or Nasopharyngeal Swab Specimens in Asymptomatic Populations
Microbiology SpectrumEngrafted Donor-Derived Clonal Hematopoiesis after Allogenic Hematopoietic Cell Transplantation is Associated with Chronic Graft-versus-Host Disease Requiring Immunosuppressive Therapy, but no Adverse Impact on Overall Survival or Relapse
Transplantation and Cellular TherapyNEDD8-activating enzyme inhibition induces cell cycle arrest and anaphase catastrophe in malignant T-cells
OncotargetRecurrent fibrin associated diffuse large B-cell lymphoma
Human Pathology: Case ReportsMolecular Discordance between Myeloid Sarcomas and Concurrent Bone Marrows Occurs in Actionable Genes and Is Associated with Worse Overall Survival
Journal of Molecular DiagnosticsReversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia
Proceedings of the National Academy of Sciences of the United States of AmericaDifferentiation of leukemic blasts is not completely blocked in acute myeloid leukemia
Proceedings of the National Academy of Sciences of the United States of AmericaNext-generation sequencing-defined minimal residual disease before stem cell transplantation predicts acute myeloid leukemia relapse
American Journal of Hematology