James McGann, Ph.D.

  • Senior Research Project Manager, CEDAR, OHSU Knight Cancer Institute, School of Medicine

Biography

James joins CEDAR with a diverse scientific history, working on yeast, frogs, human tissues, and mouse models of development and disease. These broad interests and areas of expertise are of great use in his role as Facilitator and Scientist. He especially enjoys talking about new ideas and making connections between seemingly disparate and unrelated problems. Key core principals are scientific rigor, openness, and honesty.

Publications

Publications

  • The genome-wide binding profile for human RE1 silencing transcription factor unveils a unique genetic circuitry in hippocampus

    Journal of Neuroscience
    1. James C. McGann
    2. Michael A. Spinner
    3. Saurabh K. Garg
    4. Karin A. Mullendorff
    5. Randall L. Woltjer
    6. Gail Mandel

  • Neuronal activity induces glutathione metabolism gene expression in astrocytes

    GLIA
    1. James C. McGann
    2. Gail Mandel

  • The REST remodeling complex protects genomic integrity during embryonic neurogenesis

    eLife
    1. Tamilla Nechiporuk
    2. James McGann
    3. Karin Mullendorff
    4. Jenny Hsieh
    5. Wolfgang Wurst
    6. Thomas Floss
    7. Gail Mandel

  • Polycomb- and REST-associated histone deacetylases are independent pathways toward a mature neuronal phenotype

    eLife
    1. James C. McGann
    2. Jon A. Oyer
    3. Saurabh Garg
    4. Huilan Yao
    5. Jun Liu
    6. Xin Feng
    7. Lujian Liao
    8. John R. Yates
    9. Gail Mandel

  • A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis

    eLife
    1. Virginie Olive
    2. Erich Sabio
    3. Margaux J. Bennett
    4. Caitlin S. De Jong
    5. Anne Biton
    6. James C. McGann
    7. Samantha K. Greaney
    8. Nicole M. Sodir
    9. Alicia Y. Zhou
    10. Asha Balakrishnan
    11. Mona Foth
    12. Micah A. Luftig
    13. Andrei Goga
    14. Terence P. Speed
    15. Zhenyu Xuan
    16. Gerard I. Evan
    17. Ying Wan
    18. Alex C. Minella
    19. Lin He

  • Phosphorylation of dishevelled by protein kinase RIPK4 regulates Wnt signaling

    Science
    1. Xiao Dong Huang
    2. James C. McGann
    3. Bob Y. Liu
    4. Rami N. Hannoush
    5. Jennie R. Lill
    6. Victoria Pham
    7. Kim Newton
    8. Michael Kakunda
    9. Jinfeng Liu
    10. Christine Yu
    11. Sarah G. Hymowitz
    12. Jo Anne Hongo
    13. Anthony Wynshaw-Boris
    14. Paul Polakis
    15. Richard M. Harland
    16. Vishva M. Dixit

  • Systemic delivery of MeCP2 rescues behavioral and cellular deficits in female mouse models of Rett syndrome

    Journal of Neuroscience
    1. Saurabh K. Garg
    2. Daniel T. Lioy
    3. Hélène Cheval
    4. James C. McGann
    5. John M. Bissonnette
    6. Matthew J. Murtha
    7. Kevin D. Foust
    8. Brian K. Kaspar
    9. Adrian Bird
    10. Gail Mandel