James A. Galbraith, Ph.D.
- Associate Professor of Biomedical Engineering, School of Medicine
- Discovery Engine Investigator, OHSU Knight Cancer Institute, School of Medicine
- Neuroscience Graduate Program, School of Medicine
- OHSU Knight Cancer Institute, School of Medicine
Biography
James A. Galbraith, Ph.D., combines biology, engineering and optic principles to investigate fundamental mechanisms of processes such as wiring the brain, synaptogenesis, cell division, and cell motility. His work on cellular decision making uses a combination of imaging, biophysics and neuro/cell biology to address cutting edge questions by leveraging emerging technologies.
Education and training
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Degrees
- B.S., 1981, University of Pennsylvania
- Ph.D., 1988, University of Pennsylvania
Additional information
Publications
Publications
Coupling integrin dynamics to cellular adhesion behaviors
Biology OpenChanges in single-molecule integrin dynamics linked to local cellular behavior
Molecular biology of the cellUsing Molecular Position and Dynamics to Understand Higher Order Biological Function
Microscopy and MicroanalysisRapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination
Nature MethodsSuper-resolution microscopy at a glance
Journal of Cell ScienceInterferometric fluorescent super-resolution microscopy resolves 3D cellular ultrastructure
Proceedings of the National Academy of Sciences of the United States of AmericaRapid turnover of spinules at synaptic terminals
NeuroscienceIdentifying individual scaffolding molecules in the postsynaptic density
Microscopy and MicroanalysisLive-cell photoactivated localization microscopy of nanoscale adhesion dynamics
Nature MethodsOrganization of the core structure of the postsynaptic density
Proceedings of the National Academy of Sciences of the United States of AmericaDual-color superresolution imaging of genetically expressed probes within individual adhesion complexes
Proceedings of the National Academy of Sciences of the United States of AmericaPolymerizing actin fibers position integrins primed to probe for adhesion sites
ScienceDistribution of the scaffolding proteins PSD-95, PSD-93, and SAP97 in isolated PSDs
Brain Cell BiologyControlled damage in thick specimens by multiphoton excitation
Molecular biology of the cellAxonal transport of tubulin and actin
Journal of NeurocytologySlow transport of unpolymerized tubulin and polymerized neurofilament in the squid giant axon
Proceedings of the National Academy of Sciences of the United States of AmericaAxonal structure and function after axolemmal leakage in the squid giant axon
Journal of neurotraumaA system to measure thermal nociception
Journal of Neuroscience MethodsMechanical and electrical responses of the squid giant axon to simple elongation
Journal of Biomechanical EngineeringPathology of experimental compression neuropathy producing hyperesthesia
Journal of Neuropathology and Experimental NeurologyA linearized DC lamp controller
Journal of Neuroscience MethodsSubperineurial demyelination associated with reduced nerve blood flow and oxygen tension after epineurial vascular stripping
Laboratory Investigation