Publications

• Comparison of dynamic susceptibility contrast (DSC) using gadolinium and iron-based contrast agents in high-grade glioma at high-field MRI

  Neuroradiology Journal 2024
  1. Doonyaporn Wongsawaeng
  2. Daniel Schwartz
  3. Xin Li
  4. Leslie L. Muldoon
  5. Jared Stoller
  6. Cooper Stateler
  7. Samantha Holland
  8. Laszlo Szidonya
  9. William D. Rooney
  10. Cory Wyatt
  11. Prakash Ambady
  12. Rongwei Fu
  13. Edward A. Neuwelt
  14. Ramon F. Barajas

• Deciphering spatially distinct immune microenvironments in glioblastoma using ferumoxytol and gadolinium-enhanced and FLAIR hyperintense MRI phenotypes

  Neuro-Oncology Advances Jan 1, 2023
  1. Jared Stoller
  2. Cymon N. Kersch
  3. Leslie L. Muldoon
  4. Prakash Ambady
  5. Christina A. Harrington
  6. Rongwei Fu
  7. Ahmed M. Raslan
  8. Aclan Dogan
  9. Edward A. Neuwelt
  10. Ramon F. Barajas

• Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children

  Clinical cancer research : an official journal of the American Association for Cancer Research Jul 5, 2023
  1. Etan Orgel
  2. Kristin R. Knight
  3. Yueh Yun Chi
  4. Jemily Malvar
  5. Teresa Rushing
  6. Victoria Mena
  7. Laurie S. Eisenberg
  8. Shahrad R. Rassekh
  9. Colin J.D. Ross
  10. Erika N. Scott
  11. Michael Neely
  12. Edward A. Neuwelt
  13. Leslie L. Muldoon
  14. David R. Freyer

• Multiparametric magnetic resonance imaging discerns glioblastoma immune microenvironmental heterogeneity

  Neuroradiology Journal 2023
  1. Cymon N. Kersch
  2. Leslie L. Muldoon
  3. Cheryl J. Claunch
  4. Rongwei Fu
  5. Daniel Schwartz
  6. Soonmee Cha
  7. Jay Starkey
  8. Edward A. Neuwelt
  9. Ramon F. Barajas

• 18 Fluoromisonidazole (FMISO) PET/MRI hypoxic fraction distinguishes neuroinflammatory pseudoprogression from recurrent glioblastoma in patients treated with pembrolizumab

  Neuro-Oncology Practice May 1, 2022
  1. Ramon F. Barajas
  2. Prakash Ambady
  3. Jeanne Link
  4. Kenneth A. Krohn
  5. Ahmed Raslan
  6. Nadine Mallak
  7. Randy Woltjer
  8. Leslie Muldoon
  9. Edward A. Neuwelt

• Radiation enhances the delivery of antisense oligonucleotides and improves chemo-radiation efficacy in brain tumor xenografts

  Cancer Gene Therapy 2021
  1. Prakash Ambady
  2. Yingjen Jeffrey Wu
  3. Cymon N. Kersch
  4. Joshua M. Walker
  5. Samantha Holland
  6. Leslie L. Muldoon
  7. Edward A. Neuwelt

• Safety of intra-arterial chemotherapy with or without osmotic blood-brain barrier disruption for the treatment of patients with brain tumors

  Neuro-Oncology Advances Jan 1, 2022
  1. Kutluay Uluc
  2. Prakash Ambady
  3. Matthew K. Mcintyre
  4. John Philip Tabb
  5. Cymon N. Kersch
  6. Caleb S. Nerison
  7. Amy Huddleston
  8. Jesse J. Liu
  9. Aclan Dogan
  10. Ryan A. Priest
  11. Rongwei Fu
  12. Joao Prola Netto
  13. Dominic A. Siler
  14. Leslie L. Muldoon
  15. Seymur Gahramanov
  16. Edward A. Neuwelt

• Adenosine A2A receptor activation enhances blood-tumor barrier permeability in a rodent glioma model

  Molecular Cancer Research Dec 2021
  1. Amelie Vezina
  2. Monica Manglani
  3. Dree Anna Morris
  4. Brandon Foster
  5. Matthew McCord
  6. Hua Song
  7. Meili Zhang
  8. Dionne Davis
  9. Wei Zhang
  10. Jessica Bills
  11. Kunio Nagashima
  12. Priya Shankarappa
  13. Jessica Kindrick
  14. Stuart Walbridge
  15. Cody J. Peer
  16. William D. Figg
  17. Mark R. Gilbert
  18. Dorian B. McGavern
  19. Leslie L. Muldoon
  20. Sadhana Jackson

• Blood-brain barrier opening by intracarotid artery hyperosmolar mannitol induces sterile inflammatory and innate immune responses

  Proceedings of the National Academy of Sciences of the United States of America May 4, 2021
  1. Scott R. Burks
  2. Cymon N. Kersch
  3. Jaclyn A. Witko
  4. Michael A. Pagel
  5. Maggie Sundby
  6. Leslie L. Muldoon
  7. Edward A. Neuwelt
  8. Joseph A. Frank

• High dose acetaminophen inhibits STAT3 and has free radical independent anti-cancer stem cell activity

  Neoplasia (United States) Mar 2021
  1. Pavani Pingali
  2. Y. Jeffrey Wu
  3. Rio Boothello
  4. Chetna Sharon
  5. Howard Li
  6. Srinivas Sistla
  7. Nehru Viji Sankaranarayanan
  8. Umesh R. Desai
  9. Anh T. Le
  10. Robert C. Doebele
  11. Leslie L. Muldoon
  12. Bhaumik B. Patel
  13. Alexander Neuwelt

• Distinguishing extravascular from intravascular ferumoxytol pools within the brain

  American Journal of Neuroradiology Jul 1, 2020
  1. R. F. Barajas
  2. D. Schwartz
  3. H. L. McConnell
  4. C. N. Kersch
  5. X. Li
  6. B. E. Hamilton
  7. J. Starkey
  8. D. R. Pettersson
  9. J. P. Nickerson
  10. J. M. Pollock
  11. R. F. Fu
  12. A. Horvath
  13. L. Szidonya
  14. C. G. Varallyay
  15. J. J. Jaboin
  16. A. M. Raslan
  17. A. Dogan
  18. J. S. Cetas
  19. J. Ciporen
  20. S. J. Han
  21. P. Ambady
  22. L. L. Muldoon
  23. R. Woltjer
  24. W. D. Rooney
  25. Edward A. Neuwelt

• Toll-like Receptor 4 Signaling and Downstream Neutrophilic Inflammation Mediate Endotoxemia-Enhanced Blood-Labyrinth Barrier Trafficking

  Otology and Neurotology Jan 1, 2019
  1. Zachary D. Urdang
  2. Jessica L. Bills
  3. David Y. Cahana
  4. Leslie L. Muldoon
  5. Edward A. Neuwelt

• Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival

  Neuro-Oncology Advances Jan 1, 2020
  1. Cymon N. Kersch
  2. Cheryl J. Claunch
  3. Prakash Ambady
  4. Elmar Bucher
  5. Daniel L. Schwartz
  6. Ramon F. Barajas
  7. Jeffrey J. Iliff
  8. Tyler Risom
  9. Laura Heiser
  10. Leslie L. Muldoon
  11. James E. Korkola
  12. Joe W. Gray
  13. Edward A. Neuwelt

• Combined iron oxide nanoparticle ferumoxytol and gadolinium contrast enhanced MRI define glioblastoma pseudoprogression

  Neuro-Oncology Mar 18, 2019
  1. Ramon F. Barajas
  2. Bronwyn E. Hamilton
  3. Daniel Schwartz
  4. Heather L. Mcconnell
  5. David R. Pettersson
  6. Andrea Horvath
  7. Laszlo Szidonya
  8. Csanad G. Varallyay
  9. Jenny Firkins
  10. Jerry J. Jaboin
  11. Charlotte D. Kubicky
  12. Ahmed M. Raslan
  13. Aclan Dogan
  14. Justin S. Cetas
  15. Jeremy Ciporen
  16. Seunggu J. Han
  17. Prakash Ambady
  18. Leslie L. Muldoon
  19. Randy Woltjer
  20. William D. Rooney
  21. Edward A. Neuwelt

• Cerebral blood volume mapping with ferumoxytol in dynamic susceptibility contrast perfusion MRI

  Journal of Magnetic Resonance Imaging Jan 1, 2018
  1. Csanad G. Varallyay
  2. Eric Nesbit
  3. Andrea Horvath
  4. Peter Varallyay
  5. Rongwei Fu
  6. Seymur Gahramanov
  7. Leslie L. Muldoon
  8. Xin Li
  9. William D. Rooney
  10. Edward A. Neuwelt

• Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors

  Cancer Gene Therapy Aug 1, 2017
  1. P. Ambady
  2. Y. J. Wu
  3. J. M. Walker
  4. C. Kersch
  5. M. A. Pagel
  6. R. L. Woltjer
  7. R. Fu
  8. L. L. Muldoon
  9. E. A. Neuwelt

• High αv integrin level of cancer cells is associated with development of brain metastasis in athymic rats

  Anticancer research Aug 2017
  1. Yingjen Jeffrey Wu
  2. Michael A. Pagel
  3. Leslie L. Muldoon
  4. Rongwei Fu
  5. Edward A. Neuwelt

• Ferumoxytol nanoparticle uptake in brain during acute neuroinflammation is cell-specific

  Nanomedicine: Nanotechnology, Biology, and Medicine Aug 1, 2016
  1. Heather L. McConnell
  2. Daniel L. Schwartz
  3. Brian E. Richardson
  4. Randall L. Woltjer
  5. Leslie L. Muldoon
  6. Edward A. Neuwelt

• Intra-arterial administration improves temozolomide delivery and efficacy in a model of intracerebral metastasis, but has unexpected brain toxicity

  Journal of Neuro-Oncology Feb 1, 2016
  1. Leslie L. Muldoon
  2. Michael A. Pagel
  3. Joao Prola Netto
  4. Edward A. Neuwelt

• Outwitting the Blood-Brain Barrier

  Oncology (Williston Park, N.Y.) Nov 15, 2016
  1. Edward Neuwelt
  2. Prakash Ambady
  3. Leslie Muldoon
  4. Heather McConnell
  5. Nancy Doolittle

• Interactions between αv-Integrin and HER2 and their role in the invasive phenotype of breast cancer cells in vitro and in rat brain

  PloS one Jul 29, 2015
  1. Sangeet Lal
  2. Cymon Kersch
  3. Kathleen A. Beeson
  4. Y. Jeffrey Wu
  5. Leslie L. Muldoon
  6. Edward A. Neuwelt

• N-acetylcysteine chemoprotection without decreased cisplatin antitumor efficacy in pediatric tumor models

  Journal of Neuro-Oncology Feb 2015
  1. Leslie L. Muldoon
  2. Y. Jeffrey Wu
  3. Michael A. Pagel
  4. Edward A. Neuwelt

• Vascular endothelial growth factor blockade alters magnetic resonance imaging biomarkers of vascular function and decreases barrier permeability in a rat model of lung cancer brain metastasis

  Fluids and Barriers of the CNS Feb 17, 2015
  1. Gregory L. Pishko
  2. Leslie L. Muldoon
  3. Michael A. Pagel
  4. Daniel L. Schwartz
  5. Edward A. Neuwelt

• Evaluation of pseudoprogression in patients with glioblastoma multiforme using dynamic magnetic resonance imaging with ferumoxytol calls RANO criteria into question

  Neuro-Oncology Aug 2014
  1. Morad Nasseri
  2. Seymur Gahramanov
  3. Joao Prola Netto
  4. Rongwei Fu
  5. Leslie L. Muldoon
  6. Csanad Varallyay
  7. Bronwyn E. Hamilton
  8. Edward A. Neuwelt

• Acetaminophen enhances cisplatin- and paclitaxel-mediated cytotoxicity to SKOV3 human ovarian carcinoma

  Anticancer research Jun 2013
  1. Ying Jen Jeffrey Wu
  2. Alexander J. Neuwelt
  3. Leslie L. Muldoon
  4. Edward A. Neuwelt