Louis Jeffrey Picker, M.D.

  • Professor, VGTI-Vaccine and Gene Therapy Institute
  • Molecular Microbiology and Immunology Graduate Program, School of Medicine
  • Program in Molecular and Cellular Biosciences, School of Medicine

Biography

Louis Picker graduated from UCLA with a B.S. in bacteriology in 1978 and took his M.D. degree at the University of California at San Francisco in 1982. After residency training in pathology at Beth Israel Hospital, Boston, and postdoctoral training in immunology at Stanford University Medical Center, he was appointed assistant professor and then associate professor of pathology at the University of Texas Southwestern Medical Center at Dallas. In 1999 he came to OHSU and ONPRC as professor of pathology/molecular microbiology and immunology in the OHSU School of Medicine and head of the Division of Pathobiology and Immunology.

Education and training

  • Degrees

    • B.S., 1978, UCLA
    • M.D., 1982, UCSF

Areas of interest

  • Human and primate T cell biology
  • Immunologic Memory
  • Vaccine Development

Publications

Selected publications

  • Burwitz BJ, Malouli D, Bimber BN, Reed JS, Ventura AB,Hancock MH, Uebelhoer LS, Bhusari A, Hammond KB, Espinosa Trethewy RG, Klug A, Legasse AW, Axthelm MK, Nelson JA, Park BS, Streblow DN, Hansen SG, Picker LJ,Früh K, Sacha JB. Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques. PLoS Pathog. 2016 Nov 9;12(11):e1006014. doi:10.1371/journal.ppat.1006014.[PMID: 27829026]
  • Ranasinghe S, Lamothe PA, Soghoian DZ, Kazer SW, Cole MB,Shalek AK, Yosef N, Jones RB, Donaghey F, Nwonu C, Jani P, Clayton GM, CrawfordF, White J, Montoya A, Power K, Allen TM, Streeck H, Kaufmann DE, Picker LJ,Kappler JW, Walker BD; Antiviral CD8+ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit ClonalExpansion. Immunity.2016 Oct 18;45(4):917-930. doi:10.1016/j.immuni.2016.09.015. [PMID: 27760342]
  • Greene JM, Dash P, Roy S, McMurtrey C, Awad W, Reed JS,Hammond KB, Abdulhaqq S, Wu HL, Burwitz BJ, Roth BF, Morrow DW, Ford JC, Xu G,Bae JY, Crank H, Legasse AW, Dang TH, Greenaway HY, Kurniawan M, Gold MC, Harriff MJ, Lewinsohn DA, Park BS, Axthelm MK, Stanton JJ, Hansen SG, PickerLJ, Venturi V, Hildebrand W, Thomas PG, Lewinsohn DM, Adams EJ, Sacha JB; MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates. Mucosal
  • Theiler J, Yoon H, Yusim K, Picker LJ, Fruh K, Korber B. Epigraph:A Vaccine Design Tool Applied to an HIV Therapeutic Vaccine and a Pan-Filo virus Vaccine. Sci Rep. 2016 Oct 5;6:33987. doi: 10.1038/srep33987.[PMID: 27703185]
  • Sturgill ER, Malouli D, Hansen SG, Burwitz BJ, Seo S,Schneider CL, Womack JL, Verweij MC, Ventura AB, Bhusari A, Jeffries KM,Legasse AW, Axthelm MK, Hudson AW, Sacha JB, Picker LJ, Früh K. Natural KillerCell Evasion Is Essential for Infection by Rhesus Cytomegalovirus. PLoS Pathog.2016 Aug 31;12(8):e1005868. doi: 10.1371/journal.ppat.1005868.[PMID: 27580123]

Publications