Mehrzad Sasanpour Yazdi, Ph.D.

  • Postdoctoral Scholar, CEDAR, OHSU Knight Cancer Institute, School of Medicine

Biography

Dr. Mehrzad Sasanpour received PhD in physics in the soft condensed matter field. Her research project was Dielectrophoresis (DEP) force measurement on the red blood cells (RBCs) using highly focused laser light known as Optical Tweezers (OT) at the Sharif University of Technology. In this regard, she also implemented the numerical simulation on the microelectrode structure using COMSOL to confirm the experimental quantification of DEP force based on this method. One of the main goals of this research project was to generate knowledge about the electrical properties of biological cells with a long term goal to improve disease diagnosis approaches. Her first postdoctoral position in the department of physics and biophysics at the University of San Diego (USD) was preparing and conducting the experimental visualization of the active cytoskeleton composites comprising protein filaments, including actin, microtubule (MTs), motor proteins such as myosin and kinesin that pull and push on the protein filaments, and crosslinkers such as anillin, using confocal microscopy. Moreover, she performed the image analysis to characterize the restructuring and dynamics of these active biomaterial systems to characterize and quantify to what extent the composite can be tuned according to the motor concentrations and crosslinkers. She just joined the group of Dr. Stuart Ibsen at CEDAR as a postdoctoral Scholar. Her research work focuses on enhancing the collection efficiency of cancer-derived nanoparticles and associated biomarkers from circulation using Dielectrophoresis (DEP) techniques. One of her main research interests is the development of computational approaches, including machine learning algorithms, to analyze the experimental results from the DEP-induced collection of biomarkers. She is passionate and motivated to play a key role in the CEDAR mission to detect and stop lethal cancers at earliest stages.

Publications

Publications