Molly Thomas, M.D., Ph.D. (she/her)

  • Assistant Professor of Medicine, Division of Gastroenterology and Hepatology, School of Medicine
  • Assistant Professor of Cell, Developmental and Cancer Biology, School of Medicine

Education and training

  • Degrees

    • B.S., Stanford University
    • Ph.D., University of California, San Francisco
    • M.D., University of California, San Francisco

  • Residency

    • Internal Medicine, Massachusetts General Hospital

  • Fellowship

    • Gastroenterology, Massachusetts General Hospital

  • Certifications

    • Internal Medicine, American Board of Internal Medicine
    • Gastroenterology, American Board of Internal Medicine

Memberships and associations:

  • American Gastroenterological Association
  • American Association for the Study of Liver Diseases
  • Society for Immunotherapy of Cancer

Publications

Elsevier pure profile

Selected publications

  • Blum S*, Zlotoff D*, Smith NP*, Kernin I, …Thomas MF**, Neilan T**, Reynolds KL**, and Villani AC**. Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor. BioRxiv DOI:10.1101/2023.09.15.557794 (2023). *Equal contribution **Senior Author
  • LaSalle TJ, Gonye ALK, Freeman SS, Kaplonek P, Gushterova I, Kays KR, Manakongtreecheep K, Tantivit J, Rojas-Lopez M, Russo BC, Sharma N, Thomas MF...Villani AC, Hacohen N, Sade-Feldman M. Longitudinal characterization of circulating neutrophils uncovers distinct phenotypes associated with severity in hospitalized COVID-19 patients. Cell Rep Med. 3(10):100779 (2022). PMCID: PMC9510054.
  • Thomas MF*, Slowikowski K*...Hacohen N, Reynolds KL, Li B, and Villani AC. Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define colitis associated with immune checkpoint inhibitors. bioRxiv doi: 10.1101/2021.09.17.460868 (2021). *Equal contribution
  • Galván-Peña S, Leon J, Chowdhary K…Thomas MF, Mathis D, Benoist C. Profound Treg perturbations correlate with COVID-19 severity. PNAS. 118(37) (2021) PMCID: PMC8449354.
  • Zubiri L, Molina G, Mooradian MJ, Cohen J, Durbin S, Petrillo L, Boland G, Juric D, Dougan M, Thomas MF…Villani AC, and Reynolds KL. Effect of a Multidisciplinary Severe Immunotherapy Complication Service on Outcomes for Patients Receiving Immune Checkpoint Inhibitor Therapy for Cancer. The Journal for ImmunoTherapy of Cancer, Sep;9(9): e002886 (2021). PMID 34544895.
  • Molina GE, Zubiri L, Cohen JV, Durbin SM, Petrillo L, Allen IM, Murciano-Goroff YR, Dougan M, Thomas MF…Villani AC, Reynolds KL. Temporal Trends and Outcomes Among Patients Admitted for Immune-Related Adverse Events: A Single-Center Retrospective Cohort Study from 2011 to 2018. The Oncologist. 26(6): 514-522 (2021). PMID: 33655682.
  • Reynolds K, Thomas MF, Dougan M. Diagnosis and Management of Hepatitis in Patients on Checkpoint Blockade. The Oncologist, Sep; 23(9): 991-997 (2018). PMID 29853659.
  • Thomas MF, L’Etoile N, and KM Ansel. Eri1: A conserved enzyme at the crossroads of multiple RNA-processing pathways. Trends in Genetics, 30(7): 298-307 (2014). PMID: 24929628.
  • Thomas MF, Abdul–Wajid S, Panduro M, Babiarz JE, Rajaram M, Woodruff P, Lanier LL, Heissmeyer V and KM Ansel. Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function. Blood. 120(1): 130–142 (2012). PMID 22613798.
  • Steiner DF, Thomas MF, Hu JK, Yang Z, Babiarz JE, Allen CD, Matloubian M, Blelloch R, and KM Ansel. MicroRNA–29 regulates T–box transcription factors and IFN–γ production in helper T cells. Immunity. 35(2): 169–81 (2011). PMID 21820330.
  • Thomas MF & KM Ansel. Construction of small RNA cDNA libraries for deep sequencing. In Methods in Molecular Biology: MicroRNAs and the Immune System, Vol. 667, ed. Monticelli, S. Humana Press Inc. (2010). PMID 20827529.

Publications