Monica Hinds, Ph.D.

  • Professor of Biomedical Engineering, School of Medicine
  • Assistant Dean of Graduate Student Affairs, Dean's Office, School of Medicine
  • Program in Molecular and Cellular Biosciences, School of Medicine

Biography

Dr. Monica Hinds is a Professor in the Department of Biomedical Engineering at the Oregon Health & Science University (OHSU). Prior to joining OHSU, she received degrees in Mechanical Engineering, including a B.S. from the University of Pennsylvania, an M.S. from the Georgia Institute of Technology, and a Ph.D. from the Johns Hopkins University.

Her Ph.D. dissertation work focused on the fluid mechanics involved in atherogenesis, the initiation of plaque formation in arteries. Dr. Hinds then developed elastin based biomaterials in her work at Providence St. Vincent Hospital in Portland, Oregon.

In 2003, Dr. Hinds joined the newly formed Department of Biomedical Engineering at OHSU.

Dr. Hinds’s work includes the study of biomaterials for cardiovascular applications, understanding the role of cytoskeletal structure on endothelial cell functions, and the determination of the role of hyperglycemia in causing congenital heart defects. Dr. Hinds utilizes in vitro mechanistic studies coupled with in vivo animal models to apply her engineering approaches to the causes, progression and treatment of cardiovascular diseases.

Education and training

  • Degrees

    • B.S.E., 1991, University of Pennsylvania
    • M.S., 1992, Georgia Institute of Technology
    • Ph.D., 1998, The Johns Hopkins University

Areas of interest

  • Relationship between fluid dynamics and extracellular matrix production by cells, vascular tissue engineering, role of mechanical stimulation in tissue engineered constructs, elastin based biomaterials.

Publications

Publications

  • The biological effects of copper alloying in Zn-based biodegradable arterial implants

    Biomaterials Advances
    1. Lea Morath
    2. Shebeer A. Rahim
    3. Cole Baker
    4. Deirdre E.J. Anderson
    5. Monica T. Hinds
    6. Malgorzata Sikora-Jasinska
    7. Lindy Oujiri
    8. Lisa Leyssens
    9. Greet Kerckhofs
    10. Grzegorz Pyka
    11. Alexander A. Oliver
    12. Jaroslaw W. Drelich
    13. Jeremy Goldman
  • The Effect of Rosuvastatin on a murine model of deep vein thrombosis

    Thrombosis Update
    1. Megan E. Barney
    2. Shenghao Zhou
    3. Anh Le-Cook
    4. Naly Setthavongsack
    5. Gabriel Nager
    6. Jennifer M. Loftis
    7. Randy L. Woltjer
    8. Monica Hinds
    9. Khanh P. Nguyen
  • Activation of coagulation FXI promotes endothelial inflammation and amplifies platelet activation in a nonhuman primate model of hyperlipidemia

    Research and Practice in Thrombosis and Haemostasis
    1. Tia C.L. Kohs
    2. Helen H. Vu
    3. Kelley R. Jordan
    4. Iván Parra-Izquierdo
    5. Monica T. Hinds
    6. Joseph J. Shatzel
    7. Paul Kievit
    8. Terry K. Morgan
    9. Samuel Tassi Yunga
    10. Thuy T.M. Ngo
    11. Joseph E. Aslan
    12. Michael Wallisch
    13. Christina U. Lorentz
    14. Erik I. Tucker
    15. David Gailani
    16. Jonathan R. Lindner
    17. Cristina Puy
    18. Owen J.T. McCarty
  • AMP dependent protein kinase regulates endothelial heparan sulfate expression in response to an inflammatory stimulus under arterial shear stress

    Biochemical and Biophysical Research Communications
    1. Rick Mathews
    2. Jiaqing Pang
    3. Siddharth A. Muralidaran
    4. Caitlin G.X. King
    5. Owen J.T. McCarty
    6. Monica T. Hinds
  • Comparison of bleeding and thrombotic outcomes in veno-venous extracorporeal membrane oxygenation

    European Journal of Haematology
    1. Thomas Kartika
    2. Rick Mathews
    3. Gina Migneco
    4. Taylor Bundy
    5. Andy J. Kaempf
    6. Michael Pfeffer
    7. Thomas G. DeLoughery
    8. Kerry Moore
    9. Rachel Beardshear
    10. Heath J. Oetken
    11. Jonathan Case
    12. Monica T. Hinds
    13. Owen J.T. McCarty
    14. Joseph J. Shatzel
    15. David Zonies
    16. Bishoy Zakhary
  • Effects of in utero delta-9-tetrahydrocannabinol (THC) exposure on fetal and infant musculoskeletal development in a preclinical nonhuman primate model

    PloS one
    1. Samantha A. Moellmer
    2. Olivia L. Hagen
    3. Parsa A. Farhang
    4. Victoria R. Duke
    5. Meghan E. Fallon
    6. Monica T. Hinds
    7. Owen J.T. McCarty
    8. Jamie O. Lo
    9. Karina H. Nakayama
  • Effects of in utero exposure to D-9-tetrahydrocannabinol on cardiac extracellular matrix expression and vascular transcriptome in rhesus macaques

    American Journal of Physiology - Heart and Circulatory Physiology
    1. Hillary H. Le
    2. Lyndsey Shorey
    3. Monica T. Hinds
    4. Owen McCarty
    5. Jamie Lo
    6. Deirdre Anderson
  • Factor XI Inhibition for the Prevention of Catheter-Associated Thrombosis in Patients with Cancer Undergoing Central Line Placement

    Arteriosclerosis, thrombosis, and vascular biology
    1. Michael A. Pfeffer
    2. Tia C.L. Kohs
    3. Helen H. Vu
    4. Kelley R. Jordan
    5. Jenny Si Han Wang
    6. Christina U. Lorentz
    7. Erik I. Tucker
    8. Cristina Puy
    9. Sven R. Olson
    10. Thomas G. Deloughery
    11. Monica T. Hinds
    12. Ravi S. Keshari
    13. David Gailani
    14. Florea Lupu
    15. Owen J.T. McCarty
    16. Joseph J. Shatzel
  • Ferumoxytol-enhanced MRI assessment of venous Thrombus resolution and macrophage content in a murine deep vein thrombosis model

    Thrombosis research
    1. L. Morrison
    2. B. Smoody
    3. R. Woltjer
    4. M. T. Hinds
    5. J. M. Loftis
    6. C. W. Wyatt
    7. K. P. Nguyen
  • Pharmacologic targeting of coagulation factors XII and XI by monoclonal antibodies reduces thrombosis in nitinol stents under flow

    Journal of Thrombosis and Haemostasis
    1. Novella M. Keeling
    2. Michael Wallisch
    3. Jennifer Johnson
    4. Hillary H. Le
    5. Helen H. Vu
    6. Kelley R. Jordan
    7. Cristina Puy
    8. Erik I. Tucker
    9. Khanh P. Nguyen
    10. Owen J.T. McCarty
    11. Joseph E. Aslan
    12. Monica T. Hinds
    13. Deirdre E.J. Anderson
  • Role of platelet count in a murine stasis model of deep vein thrombosis

    Platelets
    1. Rick Mathews
    2. Naly Setthavongsack
    3. Anh Le-Cook
    4. Andy Kaempf
    5. Jennifer M. Loftis
    6. Randall L. Woltjer
    7. Christina U. Lorentz
    8. Alexey Revenko
    9. Monica T. Hinds
    10. Khanh P. Nguyen
  • Temporal Changes in the Surface Chemistry and Topography of Reactive Ion Plasma-Treated Poly(vinyl alcohol) Alter Endothelialization Potential

    ACS Applied Materials and Interfaces
    1. Ryan A. Faase
    2. Novella M. Keeling
    3. Justin S. Plaut
    4. Christian Leycam
    5. Gabriela Acevedo Munares
    6. Monica T. Hinds
    7. Joe E. Baio
    8. Patrick L. Jurney
  • Thrombogenicity of biodegradable metals

    Bioactive Materials
    1. Deirdre Anderson
    2. H. H. Le
    3. H. Vu
    4. J. Johnson
    5. Joseph Aslan
    6. J. Goldman
    7. M. T. Hinds
  • Development of a novel Guinea Pig model producing transgenerational endothelial transcriptional changes driven by maternal food restriction and a second metabolic insult of high fat diet

    Frontiers in Physiology
    1. Hillary H. Le
    2. Matthew W. Hagen
    3. Samantha Louey
    4. Hagai Tavori
    5. Kent L. Thornburg
    6. George D. Giraud
    7. Monica T. Hinds
    8. Anthony P. Barnes
  • Effect of antiplatelet agents and tyrosine kinase inhibitors on oxLDL-mediated procoagulant platelet activity

    Blood Advances
    1. Tony J. Zheng
    2. Tia C.L. Kohs
    3. Paul A. Mueller
    4. Jiaqing Pang
    5. Stéphanie E. Reitsma
    6. Iván Parra-Izquierdo
    7. Alexander R. Melrose
    8. Liping Yang
    9. Jaewoo Choi
    10. Keith D. Zientek
    11. Denis O. Sviridov
    12. Mark K. Larson
    13. Craig D. Williams
    14. Nathalie Pamir
    15. Joseph J. Shatzel
    16. Ashok P. Reddy
    17. Paul Kievit
    18. Alan T. Remaley
    19. Jan F. Stevens
    20. Monica T. Hinds
    21. Owen J.T. McCarty
    22. Joseph E. Aslan
  • Fucoidan and topography modification improved in situ endothelialization on acellular synthetic vascular grafts

    Bioactive Materials
    1. Yuan Yao
    2. Aung Moe Zaw
    3. Deirdre E.J. Anderson
    4. Ye Jin Jeong
    5. Joshua Kunihiro
    6. Monica T. Hinds
    7. Evelyn K.F. Yim
  • Targeting the Contact Pathway of Coagulation for the Prevention and Management of Medical Device-Associated Thrombosis

    Seminars in thrombosis and hemostasis
    1. Abhishek Goel
    2. Harsha Tathireddy
    3. Si Han Wang
    4. Helen H. Vu
    5. Cristina Puy
    6. Monica T. Hinds
    7. David Zonies
    8. Owen J.T. McCarty
    9. Joseph J. Shatzel
  • Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function

    American journal of physiology. Cell physiology
    1. Stéphanie E. Reitsma
    2. Hari Hara Sudhan Lakshmanan
    3. Jennifer Johnson
    4. Jiaqing Pang
    5. Iván Parra-Izquierdo
    6. Alex R. Melrose
    7. Jaewoo Choi
    8. Deirdre E.J. Anderson
    9. Monica T. Hinds
    10. Jan Frederik Stevens
    11. Joseph E. Aslan
    12. Owen J.T. McCarty
    13. Jamie O. Lo
  • Hemocompatibility of micropatterned biomaterial surfaces is dependent on topographical feature size

    Frontiers in Physiology
    1. Meghan E. Fallon
    2. Hillary H. Le
    3. Novella M. Bates
    4. Yuan Yao
    5. Evelyn K.F. Yim
    6. Monica T. Hinds
    7. Deirdre E.J. Anderson
  • Ibrutinib Inhibits BMX-Dependent Endothelial VCAM-1 Expression In Vitro and Pro-Atherosclerotic Endothelial Activation and Platelet Adhesion In Vivo

    Cellular and Molecular Bioengineering
    1. Tia C.L. Kohs
    2. Sven R. Olson
    3. Jiaqing Pang
    4. Kelley R. Jordan
    5. Tony J. Zheng
    6. Aris Xie
    7. James Hodovan
    8. Matthew Muller
    9. Carrie McArthur
    10. Jennifer Johnson
    11. Bárbara B. Sousa
    12. Michael Wallisch
    13. Paul Kievit
    14. Joseph E. Aslan
    15. João D. Seixas
    16. Gonçalo J.L. Bernardes
    17. Monica T. Hinds
    18. Jonathan R. Lindner
    19. Owen J.T. McCarty
    20. Cristina Puy
    21. Joseph J. Shatzel
  • Pharmacological reduction of coagulation factor XI reduces macrophage accumulation and accelerates deep vein thrombosis resolution in a mouse model of venous thrombosis

    Journal of Thrombosis and Haemostasis
    1. Kelley R. Jordan
    2. Cory R. Wyatt
    3. Meghan E. Fallon
    4. Randy Woltjer
    5. Edward A. Neuwelt
    6. Quifang Cheng
    7. David Gailani
    8. Christina Lorentz
    9. Erik I. Tucker
    10. Owen J.T. McCarty
    11. Monica T. Hinds
    12. Khanh P. Nguyen
  • Assessment of the effects of Syk and BTK inhibitors on GPVI-mediated platelet signaling and function

    American Journal of Physiology - Cell Physiology
    1. Tony J. Zheng
    2. Elizabeth R. Lofurno
    3. Alexander R. Melrose
    4. Hari Hara Sudhan Lakshmanan
    5. Jiaqing Pang
    6. Kevin G. Phillips
    7. Meghan E. Fallon
    8. Tia C.L. Kohs
    9. Anh T.P. Ngo
    10. Joseph J. Shatzel
    11. Monica T. Hinds
    12. Owen J.T. McCarty
    13. Joseph E. Aslan
  • Characterization of a pulsatile rotary total artificial heart

    Artificial Organs
    1. Patrick L. Jurney
    2. Jeremy J. Glynn
    3. Igor V. Dykan
    4. Matthew W. Hagen
    5. Sanjiv Kaul
    6. Richard K. Wampler
    7. Monica T. Hinds
    8. George D. Giraud
  • Development of Coagulation Factor XII Antibodies for Inhibiting Vascular Device-Related Thrombosis

    Cellular and Molecular Bioengineering
    1. T. C.L. Kohs
    2. C. U. Lorentz
    3. J. Johnson
    4. C. Puy
    5. S. R. Olson
    6. J. J. Shatzel
    7. D. Gailani
    8. M. T. Hinds
    9. E. I. Tucker
    10. A. Gruber
    11. O. J.T. McCarty
    12. M. Wallisch
  • Pharmacological targeting of coagulation factor XI mitigates the development of experimental atherosclerosis in low-density lipoprotein receptor-deficient mice

    Journal of Thrombosis and Haemostasis
    1. Anh T.P. Ngo
    2. Kelley R. Jordan
    3. Paul A. Mueller
    4. Matthew W. Hagen
    5. Stéphanie E. Reitsma
    6. Cristina Puy
    7. Alexey S. Revenko
    8. Christina U. Lorentz
    9. Erik I. Tucker
    10. Quifang Cheng
    11. Monica T. Hinds
    12. Sergio Fazio
    13. Brett P. Monia
    14. David Gailani
    15. András Gruber
    16. Hagai Tavori
    17. Owen J.T. McCarty
  • Quantification of microbubble-induced sonothrombolysis in an ex vivo non-human primate model

    Journal of Thrombosis and Haemostasis
    1. Monica T. Hinds
    2. Azzdine Y. Ammi
    3. Jennifer Johnson
    4. Sanjiv Kaul