Pierre T. Moenne-Loccoz, Ph.D.

  • Professor of Chemical Physiology and Biochemistry, School of Medicine

Biography

University of Oregon, Postdoctoral Research Associate, Department of Chemistry, 1990-92

University College London, Department of Biology, 1992-93

Oregon Graduate Institute, Department of Biochemistry and Molecular Biology, 1993-96

OHSU/OGI School of Science & Engineering, Research Scientist, 1996-1999; Research Assistant Professor, 1999-2000; Assistant Professor, 2000-2007

OHSU, Institute of Environmental Health, Associate Professor, 2007-2018

Research interests: Structure-function relationships within proteins. Metalloenzymes and hemoproteins. Spectroscopic studies of enzymatic active sites, cofactors, and metal clusters. Reaction intermediates within catalysis. Nitric oxide in bioinorganic chemistry.

Education and training

  • Degrees

    • Ph.D., 1989, University Pierre & Marie Curie, Paris VI

Areas of interest

  • Bioinorganic chemistry & metalloenzymes
  • Nitric oxide biochemistry
  • Hemoprotein & heme trafficking
  • Molecular spectroscopies, kinetics, & mechanistic studies

Publications

Selected publications

  • Albert, T., Moënne-Loccoz, P. (2022) Spectroscopic characterization of a diferric mycobacterial hemerythrin-like protein with unprecedented reactivity toward nitric oxide. J. Am. Chem. Soc. 144, 17611-17621.  
  • Bhadra, M., Albert, T., Franke, A., Josef, V., Ivanovic-Burmazovic, I., Swart, M., Moënne-Loccoz, P., Karlin, K. D. (2023) Reductive coupling of nitric oxide by Cu(I): stepwise formation of mono and dinitrosyl complexes en route to a cupric hyponitrite intermediate, J. Am. Chem. Soc. 145, 2230-2242

Publications