Sherene Shalhub, M.D., M.P.H., FACS, DFSVS (she/her)

  • Professor of Surgery, Division of Vascular Surgery, School of Medicine
  • Professor of Molecular and Medical Genetics, School of Medicine
  • Division Head, Surgery, Division of Vascular Surgery, School of Medicine
  • Vice Chair for Regional Strategy and Surgical Operation, Surgery, School of Medicine

Biography

Dr. Sherene Shalhub is the Division Head of OHSU Vascular and Endovascular Surgery and is the John Porter M.D. Endowed Professor in Vascular Surgery. She co-directs the OHSU Heart and Vascular Service Line and is the Vice Chair for Regional Strategy and Surgical Operations at OHSU. She has a joint appointment in the OHSU Department of Molecular & Medical Genetics and directs the NW GAAP (Northwest Genetic Aortopathy and Arteriopathy Program).

After receiving her medical school degree from the University of South Florida in Tampa, Florida in 2003, Dr. Shalhub completed training in General Surgery in 2010 and then Vascular Surgery in 2012 at the University of Washington. She then spent a year as faculty at the University of Texas in Houston, before being recruited to join the faculty at the University of Washington where she practiced until moving to Oregon.  Her clinical practice includes a special focus on treating patients with genetically triggered aortopathies and arteriopathies such as Marfan, Loeys Dietz, and Vascular Ehlers-Danlos syndromes.

Dr. Shalhub is actively involved in research that assesses the impact of medical management and surgical procedures on patients with aortic dissections and improves the practice of surgery through education, training, and policy initiatives. Her research work is federally funded by the Patient-Centered Outcomes Research Institute (PCORI). She is the lead for the Aortic Dissection Collaborative focused on patient engagement and research prioritization for aortic dissection and is the principal investigator for the Vascular Ehlers-Danlos Syndrome Collaborative Natural History Study, a longitudinal natural history study for vascular Ehlers-Danlos syndrome. She is a distinguished fellow of the Society for Vascular Surgery, and serves on the Professional advisory board for the Marfan Foundation, and the Ehlers-Danlos Society medical and scientific board.

Education and training

  • Degrees

    • B.A., 1998, University of South Florida
    • M.P.H., 1999, University of South Florida
    • M.D., 2003, University of South Florida Morsani College of Medicine
  • Internship

    • General Surgery, University of Washington, Seattle, Wash., 2003
  • Residency

    • General Surgery, University of Washington, Seattle, Wash., 2010
  • Fellowship

    • Postdoctoral Trauma Research, University of Washington, Seattle, Wash., 2008
    • Vascular Surgery, University of Washington, Seattle, Wash., 2012
  • Certifications

    • American Board of Surgery, Vascular Surgery, 2018

Memberships and associations:

  • Society for Vascular Surgery
  • Vascular and Endovascular Surgery Society
  • American Heart Association
  • American College of Surgeons, Fellow
  • Society for Clinical Vascular Surgery
  • The Association of Women Surgeons
  • Society for Vascular Medicine

Areas of interest

  • Genetic Aortopathy

Honors and awards

  • University of Washington Medicine PRAISE (Patient Reported Assessment in Satisfaction and Excellence) Award, 2016
  • Seattle Top Doctor, 2020
  • Vascular Cures #VascularHero, 2020
  • The Ehlers-Danlos Society Pioneer in EDS and HSD Research Award, 2021

Publications

Elsevier pure profile

Publications

  • Aortic and arterial manifestations and clinical features in TGFB3 -related heritable thoracic aortic disease

    Journal of medical genetics
    1. Michelle Su Anne Lim
    2. Dong Chuan Guo
    3. Walter Velasco Torrez
    4. Andrew Lai
    5. Jonathan Schweber
    6. Nikita Garg
    7. Julie Fleischer
    8. Catherine Boileau
    9. Julie De Backer
    10. Artur Evangelista
    11. Guillaume Jondeau
    12. Carine Le Goff
    13. Olivier Milleron
    14. Laura Muiño-Mosquera
    15. Shaine Morris
    16. Maral Ouzounian
    17. Elena Cervi
    18. Julien Marcadier
    19. Anthony Caffarelli
    20. Sherene Shalhub
    21. Reed Pyeritz
    22. Angela Yetman
    23. Dianna Milewicz
    24. Alan C. Braverman
  • Natural history of the distal aorta following elective root replacement in patients with Marfan syndrome

    Journal of Thoracic and Cardiovascular Surgery
    1. Arjune S. Dhanekula
    2. Rachel Flodin
    3. Palcah Shibale
    4. Joseph Volk
    5. Thoetphum Benyakorn
    6. Scott DeRoo
    7. Sherene Shalhub
    8. Christopher R. Burke
  • Complicated and Uncomplicated Isolated Abdominal Aortic Dissections Demonstrate Different Patient Characteristics and Outcomes

    Annals of Vascular Surgery
    1. James M. Dittman
    2. Thoetphum Benyakorn
    3. Nicolas J. Mouawad
    4. Zhanjiang Cao
    5. Jasmin Etafo
    6. Elina Quiroga
    7. Benjamin W. Starnes
    8. Sherene Shalhub
  • Elective root replacement increases the risk of type B dissection in patients with Marfan syndrome

    Journal of Thoracic and Cardiovascular Surgery
    1. Ryan Thomas
    2. Arjune S. Dhanekula
    3. Peter Byers
    4. Rachel Flodin
    5. Scott DeRoo
    6. Sherene Shalhub
    7. Christopher R. Burke
  • Experience with Zone 2 Arch Replacement Followed by Thoracic Endovascular Aortic Repair

    AORTA
    1. Arjune Dhanekula
    2. Bret DeGraaff
    3. Rachel Flodin
    4. Anne Reimann-Moody
    5. Manuel De La Garza
    6. Sara Zettervall
    7. Sherene Shalhub
    8. Matthew P. Sweet
    9. Christopher R. Burke
    10. Scott DeRoo
  • Heparin-Induced Thrombocytopenia (HIT) in the Direct Oral Anticoagulants (DOAC) Era

    Annals of Vascular Surgery
    1. Reid C. Mahoney
    2. Thomas G. DeLoughery
    3. Enjae Jung
    4. Sherene Shalhub
    5. Timothy K. Liem
  • Iliac artery dissection and rupture in a patient with classic Ehlers-Danlos syndrome due to COL5A1 null variant

    Journal of Vascular Surgery Cases, Innovations and Techniques
    1. Amit Pujari
    2. Sherene Shalhub
  • Impact of COVID-19 on patients undergoing scheduled procedures for chronic venous disease

    Vascular
    1. Ethan Moore
    2. Max V. Wohlauer
    3. James Dorosh
    4. Mahmood Kabeil
    5. Rafael D. Malgor
    6. Leigh A. O’Banion
    7. Gabriel Lopez-Pena
    8. Riley Gillette
    9. Kathryn Colborn
    10. Robert F. Cuff
    11. Leah Lucero
    12. Amna Ali
    13. Issam Koleilat
    14. Paola Batarseh
    15. Sonia Talathi
    16. Aksim Rivera
    17. Misty D. Humphries
    18. Kevin Ly
    19. Nikolai Harroun
    20. Brigitte K. Smith
    21. Anna M. Darelli-Anderson
    22. Asad Choudhry
    23. Eric Hammond
    24. Michael Costanza
    25. Vipul Khetarpaul
    26. Ashley Cosentino
    27. Jacob Watson
    28. Rana Afifi
    29. Nicolas J. Mouawad
    30. Tze Woei Tan
    31. Mel Sharafuddin
    32. Judith P. Quevedo
    33. Reggie Nkansah
    34. Palcah Shibale
    35. Sherene Shalhub
    36. Judith C. Lin
  • Long term follow up after TEVAR for pediatric blunt thoracic aortic injury

    Annals of Vascular Surgery - Brief Reports and Innovations
    1. Eni Nako
    2. Kelsi Hirai
    3. Sherene Shalhub
    4. Amani D. Politano
  • Open repair of a ruptured abdominal aorta with an aortoiliac vein fistula in a 7-month-old infant and review of the literature

    Journal of Vascular Surgery Cases, Innovations and Techniques
    1. Olivia I. Fuson
    2. Kelsi Hirai
    3. Devin R. Halleran
    4. Mubeen Jafri
    5. Ashok Muralidaran
    6. Amir Azarbal
    7. Cherrie Z. Abraham
    8. Sherene Shalhub
  • Practice Patterns and Barriers to Vascular Genetic Testing Among Vascular Surgeons

    Annals of Vascular Surgery
    1. James M. Dittman
    2. Siddharth K. Prakash
    3. Prem Chand Gupta
    4. Wojciech Wiszniewski
    5. Niten Singh
    6. Matthew R. Smeds
    7. Sherene Shalhub
  • A multidisciplinary multistage complete mega aorta replacement and utilization of extracorporeal membrane oxygenation in thoracoabdominal aneurysm repair

    Journal of Vascular Surgery Cases, Innovations and Techniques
    1. Nallely Saldana-Ruiz
    2. Karanpreet Dhaliwal
    3. Trang N. Bodtke
    4. Christopher R. Burke
    5. Matthew P. Sweet
    6. Sherene Shalhub
  • A systematic review supporting the Society for Vascular Surgery guidelines on the management of heritable aortopathies

    Journal of vascular surgery
    1. Mohammed Firwana
    2. Bashar Hasan
    3. Samer Saadi
    4. Rami Abd-Rabu
    5. Khaled Alabdallah
    6. Hossam Al-Zu'bi
    7. Sherene Shalhub
    8. James H. Black
    9. Larry J. Prokop
    10. M. Hassan Murad
  • Carotid Artery Operation Delay During the Covid-19 Pandemic

    Annals of Vascular Surgery
    1. Mahmood Kabeil
    2. Max V. Wohlauer
    3. Mario D'Oria
    4. Vipul Khetarpaul
    5. Riley Gillette
    6. Ethan Moore
    7. Kathryn Colborn
    8. Robert F. Cuff
    9. Leigh Ann O'Banion
    10. Issam Koleilat
    11. Faisal Aziz
    12. Nicolas J. Mouawad
    13. Leigh Ann O'Banion
    14. Amna Ali
    15. Leah Lucero
    16. Michael Costanza
    17. Eric Hammond
    18. Raghunandan L. Motaganahalli
    19. Humraaz Samra
    20. Gregory G. Westin
    21. Kara Allen
    22. Ulka Sachdev
    23. Elizabeth A. Andraska
    24. Mel Sharafuddin
    25. Judith Pena-Quevedo
    26. Matthew Carnevale
    27. Paola Batarseh
    28. Britt H. Tonnessen
    29. Nikolai Harroun
    30. Agnese Sataviciute
    31. Giovanni Tinelli
    32. Jason Chuen
    33. Jonathan Bath
    34. Joseph L. Mills
    35. Rana O. Afifi
    36. Raphaël Coscas
    37. Sherene Shalhub
    38. Reggie Nkansah
    39. Adam W. Beck
    40. Rebecca St. John
    41. Fatemeh Malekpour
    42. Michael Siah
    43. Sooyeon Kim
    44. Mark G. Davies
    45. Grace Ihsiu Todd
    46. Courtney Busby
    47. Peter R. Nelson
    48. Sydney Wyatt
    49. Sana Ahmed
    50. Ashley Cosentino
  • Endovascular repair of a common iliac artery aneurysm with an iliac branch device in a patient with vascular Ehlers-Danlos syndrome due to a null COL3A1 variant

    Journal of Vascular Surgery Cases, Innovations and Techniques
    1. Sherene Shalhub
    2. Peter H. Byers
  • Initial Thoracic Endovascular Aortic Repair vs Medical Therapy for Acute Uncomplicated Type B Aortic Dissection

    JAMA Cardiology
    1. E. Hope Weissler
    2. Oyomoare L. Osazuwa-Peters
    3. Melissa A. Greiner
    4. N. Chantelle Hardy
    5. Panagiotis Kougias
    6. Sean M. O'Brien
    7. Daniel B. Mark
    8. W. Schuyler Jones
    9. Eric A. Secemsky
    10. Andrew M. Vekstein
    11. Sherene Shalhub
    12. Firas F. Mussa
    13. Manesh R. Patel
    14. Sreekanth Vemulapalli
  • Obstetric considerations for aortopathy in pregnancy

    Annals of Cardiothoracic Surgery
    1. Anna R. Whelan
    2. Myles E. Ringel
    3. Sherene Shalhub
    4. Melissa L. Russo
  • Open repair of abdominal aortic aneurysms in patients with vascular Ehlers-Danlos syndrome

    Journal of Vascular Surgery Cases, Innovations and Techniques
    1. James M. Dittman
    2. Nallely Saldana-Ruiz
    3. Karina Newhall
    4. Peter H. Byers
    5. Benjamin W. Starnes
    6. Sherene Shalhub
  • Operative repair of right intrathoracic subclavian artery aneurysms in patients with genetic arteriopathy

    Journal of Vascular Surgery Cases, Innovations and Techniques
    1. Bryce L. French
    2. Anthony M. Menghini
    3. Christopher R. Burke
    4. Peter H. Byers
    5. Sherene Shalhub
  • Splenic artery pathology presentation, operative interventions, and outcomes in 88 patients with vascular Ehlers-Danlos syndrome

    Journal of vascular surgery
    1. Sherene Shalhub
    2. Reginald Nkansah
    3. Asmaa El-Ghazali
    4. Charles J. Hillenbrand
    5. Sandeep S. Vaidya
    6. Ulrike Schwarze
    7. Peter H. Byers
  • Vertebral Tortuosity Is Associated With Increased Rate of Cardiovascular Events in Vascular Ehlers-Danlos Syndrome

    Journal of the American Heart Association
    1. Sara B. Stephens
    2. Sherene Shalhub
    3. Nicholas Dodd
    4. Jesse Li
    5. Michael Huang
    6. Seitaro Oda
    7. Kalyan Kancherla
    8. Tam T. Doan
    9. Siddharth K. Prakash
    10. Justin D. Weigand
    11. Federico M. Asch
    12. Taylor Beecroft
    13. Alana Cecchi
    14. Teniola Shittu
    15. Liliana Preiss
    16. Scott A. Lemaire
    17. Richard B. Devereux
    18. Reed E. Pyeritz
    19. Kathryn W. Holmes
    20. Mary J. Roman
    21. Ronald V. Lacro
    22. Ralph V. Shohet
    23. Rajesh Krishnamurthy
    24. Kim Eagle
    25. Peter Byers
    26. Dianna M. Milewicz
    27. Shaine A. Morris
  • A mixed method approach to understanding the impact of COVID-19 on patients with or at risk for aortic dissection

    Seminars in Vascular Surgery
    1. Jenney R. Lee
    2. Courtney Segal
    3. Jake Howitt
    4. Timo Soderlund
    5. Novelette Cotter
    6. Melanie Case
    7. Debra Trotter
    8. Sarah O. Lawrence
    9. Sherene Shalhub
    10. Josephine Grima
    11. Kim Eagle
    12. Kim Eagle
    13. Eva Klein-Rogers
    14. Karen Woo
    15. Peter Byers
    16. Dianna Milewicz
    17. Firas Mussa
    18. Melanie Case
    19. Novelett E. Cotter
    20. Carmen C. David
    21. Mark Fasano
    22. Richard Goldenberg
    23. Jake Howitt
    24. Timo T. Söderlund
    25. Debra Trotter
    26. Asaf Rabin
    27. Mattie Boehler-Tatman
    28. Melissa L. Russo
    29. Laura Marie Drudi
    30. Laura L. Marks
    31. Maisoon D. Yousif
    32. Tabea Hoffstaetter
    33. Ella Taubenfeld
    34. Sreekanth Vemulapalli
    35. Chrisanne S. Campos
    36. Lindsey Rusche
    37. Robert C.F. Pena
    38. Firas F. Mussa
    39. Gretchen MacCarrick
    40. Earl Goldsborough
    41. Christeen Samuel
    42. Lillian Xu
    43. Nicolas J. Mouawad
    44. Eanas S. Yassa
    45. Xiaoyi Teng
    46. Amani Politano
    47. Jesse Teindl
    48. Lara Bloom
    49. Rebecca Gluck
    50. Meredith Ford O'Neal