Publications

• First-in-Human Study of 23ME-00610, an Antagonistic Antibody for Genetically Validated CD200R1 Immune Checkpoint, in Participants with Advanced Solid Malignancies

  Cancer Research Communications Jan 2025
  1. Shivaani Kummar
  2. Albiruni Abdul Razak
  3. Scott Laurie
  4. Dylan M. Glatt
  5. Sariah Kell
  6. Anh N. Diep
  7. Maike Schmidt
  8. Clifford Hom
  9. Chris German
  10. Suyash S. Shringarpure
  11. Sophia R. Majeed
  12. Drew Rasco

• Immunologic signatures of response and resistance to nivolumab with ipilimumab in advanced metastatic cancer

  Journal of Experimental Medicine Oct 7, 2024
  1. Apostolia M. Tsimberou
  2. Farah A. Alayli
  3. Kwame Okrah
  4. Alexandra Drakaki
  5. Danny N. Khalil
  6. Shivaani Kummar
  7. Saad A. Khan
  8. F. Stephen Hodi
  9. Dav Y. Oh
  10. Christopher R. Cabanski
  11. Shikha Gautam
  12. Stefanie L. Meier
  13. Meelad Amouzgar
  14. Shannon M. Pfeiffer
  15. Robin Kageyama
  16. Enjun Yang
  17. Marko Spasic
  18. Michael T. Tetzlaff
  19. Wai Chin Foo
  20. Travis J. Hollmann
  21. Yanyun Li
  22. Matthew Adamow
  23. Phillip Wong
  24. Jonni S. Moore
  25. Sharlene Velichko
  26. Richard O. Chen
  27. Dinesh Kumar
  28. Samantha Bucktrout
  29. Ramy Ibrahim
  30. Ute Dugan
  31. Lisa Salvador
  32. Vanessa M. Hubbard-Lucey
  33. Jill O’donnell-Tormey
  34. Sandra Santulli-Marotto
  35. Lisa H. Butterfield
  36. Diane M. Da Silva
  37. Justin Fairchild
  38. Theresa M. Lavallee
  39. Lacey J. Padrón
  40. Padmanee Sharma

• ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Nab-Paclitaxel in Patients with Advanced Solid Tumors

  Cancer Research Communications Sep 2024
  1. Christopher T. Chen
  2. Vishesh Khanna
  3. Shivaani Kummar
  4. Raghad M. Abdul-Karim
  5. David Sommerhalder
  6. Anthony W. Tolcher
  7. Naoto T. Ueno
  8. Sarah Lindsey Davis
  9. Douglas W. Orr
  10. Erika Hamilton
  11. Manish R. Patel
  12. Alexander I. Spira
  13. Shekeab Jauhari
  14. Vaia Florou
  15. Maureen Duff
  16. Rongda Xu
  17. Jian Wang
  18. Shravani R. Barkund
  19. Haiying Zhou
  20. Aleksandr Pankov
  21. Wayne Kong
  22. Nadine S. Jahchan
  23. Erica L. Jackson
  24. Jessica D. Sun
  25. Melissa R. Junttila
  26. Pratik S. Multani
  27. Anneleen Daemen
  28. Edna Chow Maneval
  29. Pamela N. Munster

• Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors

  Cancer Chemotherapy and Pharmacology 2023
  1. Arjun Mittra
  2. Geraldine H.O’ Sullivan Coyne
  3. Jennifer Zlott
  4. Shivaani Kummar
  5. Robert Meehan
  6. Lawrence Rubinstein
  7. Lamin Juwara
  8. Deborah Wilsker
  9. Jiuping Ji
  10. Brandon Miller
  11. Tony Navas
  12. Katherine V. Ferry-Galow
  13. Andrea Regier Voth
  14. Ting Chia Chang
  15. Shahanawaz Jiwani
  16. Ralph E. Parchment
  17. James H. Doroshow
  18. Alice P. Chen

• Phase I Study of GS-3583, an FMS-like Tyrosine Kinase 3 Agonist Fc Fusion Protein, in Patients with Advanced Solid Tumors

  Clinical Cancer Research Jul 15, 2024
  1. Anthony W. Tolcher
  2. Joshua D. Brody
  3. Nishanthan Rajakumaraswamy
  4. Michelle Kuhne
  5. Torsten Trowe
  6. Anees M. Dauki
  7. Shantheri Pai
  8. Ling Han
  9. Kai Wen Lin
  10. Michael Petrarca
  11. Shivaani Kummar

• The effect of liver dysfunction on the pharmacokinetic disposition of belinostat and its five metabolites in patients with advanced cancers

  Cancer Chemotherapy and Pharmacology 2024
  1. Allison Dunn
  2. Naoko Takebe
  3. Alice Chen
  4. Shivaani Kummar
  5. Richard Piekarz
  6. Brian Kiesel
  7. Nancy Moore
  8. James Doroshow
  9. Jan H. Beumer
  10. Jogarao V.S. Gobburu

• The ESMO Tumour-Agnostic Classifier and Screener (ETAC-S)

  Annals of Oncology Nov 2024
  1. C. B. Westphalen
  2. D. Martins-Branco
  3. J. R. Beal
  4. C. Cardone
  5. N. Coleman
  6. A. M. Schram
  7. S. Halabi
  8. S. Michiels
  9. C. Yap
  10. F. André
  11. F. Bibeau
  12. G. Curigliano
  13. E. Garralda
  14. S. Kummar
  15. R. Kurzrock
  16. S. Limaye
  17. S. Loges
  18. A. Marabelle
  19. C. Marchió
  20. J. Mateo
  21. J. Rodon
  22. T. Spanic
  23. G. Pentheroudakis
  24. V. Subbiah

• Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization

  Cell Reports Medicine Sep 17, 2024
  1. Sushil Kumar
  2. Dhanir Tailor
  3. Arpit Dheeraj
  4. Wenqi Li
  5. Kirsten Stefan
  6. Jee Min Lee
  7. Dylan Nelson
  8. Bailey F. Keefe
  9. Pepper Schedin
  10. Shivaani Kummar
  11. Lisa M. Coussens
  12. Sanjay V. Malhotra

• Evaluating the indotecan–neutropenia relationship in patients with solid tumors by population pharmacokinetic modeling and sigmoidal E _max regressions

  Cancer Chemotherapy and Pharmacology 2023
  1. Jan H. Beumer
  2. Benjamin C. Kennard
  3. Julianne L. Holleran
  4. Nancy Moore
  5. Jennifer Zlott
  6. Brian M. Miller
  7. Shivaani Kummar
  8. Alice Chen
  9. James Doroshow
  10. Wansu Park
  11. Jogarao Gobburu
  12. Allison Dunn

• Larotrectinib efficacy and safety in adult patients with tropomyosin receptor kinase fusion sarcomas

  Cancer Dec 1, 2023
  1. Shivaani Kummar
  2. Lin Shen
  3. David S. Hong
  4. Ray McDermott
  5. Vicki L. Keedy
  6. Michela Casanova
  7. George D. Demetri
  8. Afshin Dowlati
  9. Soledad Gallego Melcón
  10. Ulrik N. Lassen
  11. Serge Leyvraz
  12. Tianshu Liu
  13. Victor Moreno
  14. Jyoti Patel
  15. Tejas Patil
  16. Atrayee Basu Mallick
  17. Nuno Sousa
  18. Makoto Tahara
  19. David S. Ziegler
  20. Ricarda Norenberg
  21. Pierre Arvis
  22. Nicoletta Brega
  23. Alexander Drilon
  24. Daniel S.W. Tan

• Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors.

  New England Journal of Medicine 2023
  1. Mrinal Gounder
  2. Ravin Ratan
  3. Thierry Alcindor
  4. Patrick Schöffski
  5. Winette T. Van Der Graaf
  6. Breelyn A. Wilky
  7. Richard F. Riedel
  8. Allison Lim
  9. L. Mary Smith
  10. Stephanie Moody
  11. Steven Attia
  12. Sant Chawla
  13. Gina D'Amato
  14. Noah Federman
  15. Priscilla Merriam
  16. Brian A. Van Tine
  17. Bruno Vincenzi
  18. Charlotte Benson
  19. Nam Quoc Bui
  20. Rashmi Chugh
  21. Gabriel Tinoco
  22. John Charlson
  23. Palma Dileo
  24. Lee Hartner
  25. Lore Lapeire
  26. Filomena Mazzeo
  27. Emanuela Palmerini
  28. Peter Reichardt
  29. Silvia Stacchiotti
  30. Howard H. Bailey
  31. Melissa A. Burgess
  32. Gregory M. Cote
  33. Lara E. Davis
  34. Hari Deshpande
  35. Hans Gelderblom
  36. Giovanni Grignani
  37. Elizabeth Loggers
  38. Tony Philip
  39. Joseph G. Pressey
  40. Shivaani Kummar
  41. Bernd Kasper

• Predicting Response of Triple-Negative Breast Cancer to Neoadjuvant Chemotherapy Using a Deep Convolutional Neural Network-Based Artificial Intelligence Tool

  JCO Clinical Cancer Informatics 2023
  1. Savitri Krishnamurthy
  2. Parag Jain
  3. Debu Tripathy
  4. Roland Basset
  5. Ramandeep Randhawa
  6. Hassan Muhammad
  7. Wei Huang
  8. Hua Yang
  9. Shivaani Kummar
  10. George Wilding
  11. Rajat Roy

• Randomized Phase II Trial of Sunitinib or Cediranib in Alveolar Soft Part Sarcoma

  Clinical Cancer Research Apr 1, 2023
  1. James Nguyen
  2. Naoko Takebe
  3. Shivaani Kummar
  4. Albiruni Razak
  5. Sant P. Chawla
  6. Suzanne George
  7. Shreyaskumar R. Patel
  8. Mary Louise Keohan
  9. Sujana Movva
  10. Geraldine O’Sullivan Coyne
  11. Khanh Do
  12. Lamin Juwara
  13. Brooke Augustine
  14. Seth M. Steinberg
  15. Laura Kuhlmann
  16. S. Percy Ivy
  17. James H. Doroshow
  18. Alice P. Chen

• A Novel Artificial Intelligence–Powered Method for Prediction of Early Recurrence of Prostate Cancer after Prostatectomy and Cancer Drivers

  JCO Clinical Cancer Informatics 2022
  1. Wei Huang
  2. Ramandeep Randhawa
  3. Parag Jain
  4. Samuel Hubbard
  5. Jens Eickhoff
  6. Shivaani Kummar
  7. George Wilding
  8. Hirak Basu
  9. Rajat Roy

• Clinical Activity of Single-Agent Cabozantinib (XL184), a Multi-receptor Tyrosine Kinase Inhibitor, in Patients with Refractory Soft-Tissue Sarcomas

  Clinical Cancer Research Jan 15, 2022
  1. Geraldine O’Sullivan Coyne
  2. Shivaani Kummar
  3. James Hu
  4. Kristen Ganjoo
  5. Warren A. Chow
  6. Khanh T. Do
  7. Jennifer Zlott
  8. Ashley Bruns
  9. Lawrence Rubinstein
  10. Jared C. Foster
  11. Lamin Juwara
  12. Robert Meehan
  13. Richard Piekarz
  14. Howard Streicher
  15. Elad Sharon
  16. Naoko Takebe
  17. Andrea Regier Voth
  18. Donald Bottaro
  19. Rene Costello
  20. John J. Wright
  21. James H. Doroshow
  22. Alice P. Chen

• Comparative Effectiveness of Larotrectinib and Entrectinib for TRK Fusion Cancer

  American Journal of Managed Care 2022
  1. Josh J. Carlson
  2. Antoine Italiano
  3. Marcia S. Brose
  4. Noah Federman
  5. Ulrik Lassen
  6. Shivaani Kummar
  7. Sean D. Sullivan

• Diagnosis and Management of TRK Fusion Cancer

  American Journal of Managed Care 2022
  1. Shivaani Kummar
  2. Antoine Italiano
  3. Marcia S. Brose
  4. Josh J. Carlson
  5. Sean D. Sullivan
  6. Ulrik Lassen
  7. Noah Federman

• Efficacy and safety of larotrectinib in patients with TRK fusion-positive thyroid carcinoma

  European journal of endocrinology Jun 2022
  1. Steven G. Waguespack
  2. Alexander Drilon
  3. Jessica J. Lin
  4. Marcia S. Brose
  5. Ray McDermott
  6. Mohammed Almubarak
  7. Jessica Bauman
  8. Michela Casanova
  9. Anuradha Krishnamurthy
  10. Shivaani Kummar
  11. Serge Leyvraz
  12. Do Youn Oh
  13. Keunchil Park
  14. Davendra Sohal
  15. Eric Sherman
  16. Ricarda Norenberg
  17. Josh D. Silvertown
  18. Nicoletta Brega
  19. David S. Hong
  20. Maria E. Cabanillas

• Efficacy and Safety of Larotrectinib in Patients With Tropomyosin Receptor Kinase Fusion–Positive Lung Cancers

  JCO Precision Oncology 2022
  1. Alexander Drilon
  2. Daniel S.W. Tan
  3. Ulrik N. Lassen
  4. Serge Leyvraz
  5. Yongmei Liu
  6. Jyoti D. Patel
  7. Lee Rosen
  8. Benjamin Solomon
  9. Ricarda Norenberg
  10. Laura Dima
  11. Nicoletta Brega
  12. Lin Shen
  13. Victor Moreno
  14. Shivaani Kummar
  15. Jessica J. Lin

• First-in-Human Phase I/II ICONIC Trial of the ICOS Agonist Vopratelimab Alone and with Nivolumab

  Clinical Cancer Research Sep 1, 2022
  1. Timothy A. Yap
  2. Justin F. Gainor
  3. Margaret K. Callahan
  4. Gerald S. Falchook
  5. Russell K. Pachynski
  6. Patricia LoRusso
  7. Shivaani Kummar
  8. Geoffrey T. Gibney
  9. Howard A. Burris
  10. Scott S. Tykodi
  11. Osama E. Rahma
  12. Tanguy Y. Seiwert
  13. Kyriakos P. Papadopoulos
  14. Mariela Blum Murphy
  15. Haeseong Park
  16. Amanda Hanson
  17. Yasmin Hashambhoy-Ramsay
  18. Lara McGrath
  19. Ellen Hooper
  20. Xiaoying Xiao
  21. Heather Cohen
  22. Martin Fan
  23. Daniel Felitsky
  24. Courtney Hart
  25. Rachel McComb
  26. Karen Brown
  27. Ali Sepahi
  28. Judith Jimenez
  29. Weidong Zhang
  30. Johan Baeck
  31. Haley Laken
  32. Richard Murray
  33. Elizabeth Trehu
  34. Christopher J. Harvey

• Combination therapy with pazopanib and tivantinib modulates VEGF and c-MET levels in refractory advanced solid tumors

  Investigational New Drugs Dec 2021
  1. Shivaani Kummar
  2. Apurva K. Srivastava
  3. Tony Navas
  4. Fabiola Cecchi
  5. Young H. Lee
  6. Donald P. Bottaro
  7. Sook Ryun Park
  8. Khanh T. Do
  9. Woondong Jeong
  10. Barry C. Johnson
  11. Andrea R. Voth
  12. Larry Rubinstein
  13. John J. Wright
  14. Ralph E. Parchment
  15. James H. Doroshow
  16. Alice P. Chen

• First-in-human study of PF-06647020 (cofetuzumab pelidotin), an antibody-drug conjugate targeting protein tyrosine kinase 7, in advanced solid tumors

  Clinical Cancer Research Aug 15, 2021
  1. Michael L. Maitland
  2. Jasgit C. Sachdev
  3. Manish R. Sharma
  4. Victor Moreno
  5. Valentina Boni
  6. Shivaani Kummar
  7. Erica Stringer-Reasor
  8. Nehal Lakhani
  9. Allison R. Moreau
  10. Dawei Xuan
  11. Ray Li
  12. Eric L. Powell
  13. Amy Jackson-Fisher
  14. Michelle Bowers
  15. Shilpa Alekar
  16. Xiaohua Xin
  17. Anthony W. Tolcher
  18. Emiliano Calvo

• Molecular profiling-based assignment of cancer therapy (NCI-MPACT)

  JCO Precision Oncology Jan 2021
  1. Alice P. Chen
  2. Shivaani Kummar
  3. Nancy Moore
  4. Lawrence V. Rubinstein
  5. Yingdong Zhao
  6. P. Mickey Williams
  7. Alida Palmisano
  8. David Sims
  9. Geraldine O'Sullivan Coyne
  10. Christina L. Rosenberger
  11. Mel Simpson
  12. Kanwal P.S. Raghav
  13. Funda Meric-Bernstam
  14. Stephen Leong
  15. Saiama Waqar
  16. Jared C. Foster
  17. Mariam M. Konaté
  18. Biswajit Das
  19. Chris Karlovich
  20. Chih Jian Lih
  21. Eric Polley
  22. Richard Simon
  23. Ming Chung Li
  24. Richard Piekarz
  25. James H. Doroshow