Current research in the Scanlan Lab is focused on understanding thyroid hormone action at the molecular, cellular, and organismal level to facilitate the development of novel thyroid hormone based therapeutic agents.  Thyroid hormone regulates important processes in the central nervous system and periphery, and development of tissue-selective thyroid hormone agonists and antagonists as both research tools and therapeutic agents is an active component of the lab's research.  The lab also investigates the chemistry and biology activity of novel thyroid hormone metabolites in an effort to use these endogenous iodine-containing compounds as therapeutic or diagnostic agents.