Portland Alcohol Research Center Research Resources
Data Sharing
The Portland Alcohol Research Center (PARC) submits data to established and centralized archives according to data type. We continue in-house to integrate and store larger collections of data that are available to PARC researchers. These data may be made available to outside investigators upon request.
Animal Models
The PARC utilizes many genetic animal models. Mouse genetic models developed locally by PARC researchers are now available to the broader research community.
The Monkey Alcohol Tissue Research Resource (MATRR) has brain and body tissue as well as complete alcohol self-administration data sets from rhesus macaques under alcohol self-administration protocols. Visit the website.
High-Confidence Strain Specific Splicing (SSS) Events Found within Collaborative Cross (CC) Founder Strains
The Collaborative Cross (CC) is a large panel of genetically diverse recombinant inbred mouse strains specifically designed to provide a systems genetics resource for the study of complex traits. The founder strains include five classical inbred laboratory strains {C57BL/6 (B6), 129S1/SvlmJ (129), A/J (AJ), NOD/LtJ (NOD), and NZO/HILtJ (NZO)} and three wild-derived strains {CAST/EiJ (CAST), PWK/PhJ (PWK) and WSB/EiJ (WSB)}. Through deep transcriptome sequencing, a large number of high-confidence SSS events were identified within each strain. High-confidence Strain Specific Splicing (SSS) events are defined as exon-exon junctions that 1) are uniquely found in one strain, 2) had a read coverage ≥ 10 and 3) are defined by a canonical splice site.
Portland Alcohol Research Center Library
While the PARC is primarily engaged in pre-clinical research, we field a variety of requests for information. In order to be responsive to the wider community, the Library keeps on hand local referral information and general publications from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA). These items have been especially valuable when the PARC responds to requests for clinical information from private individuals, alcohol & drug treatment clinicians, and clinicians from other specialties. The Library also holds alcohol epidemiological reports, assessment and treatment guides, statistical references, and outreach and educational materials such as NIH curricula focused on addictions. These resources have been beneficial to PARC investigators and students, particularly as they translate the salience of their research to the public in the context of broader addiction issues.