MR BIOGEN 101MS326 / "ASCEND" / Tysrabi Research Protocol

Scan Notes:

  • The study drug is Tysrabi, so it may accidentally be called the “Tysrabi Study”.
  • Dosing is to the 10th (e.g 0.1) with NO MAXIMUM dosing (can give MORE THAN 10mL)

Last updated: 4/12/19
Charge as Brain WWO, "No protocol required", YES READ
Scanner preference: MR3 only
Coil: Head Coil

Sequence Weighting Change Parameters? Change # slices? Coverage/ Angulation Notes
SAG MIDLINE NO NO To True Midline
AX TEST NO NO To AC-PC Line
AX PD NO NO To AC-PC Line
AX T2 NO NO To AC-PC Line
AX 3DT1 NO NO To AC-PC Line Coverage to include 2-3 slices of air above the top of the head

Contrast injection

  1. Contrast should be administered over a 1 minute period.
  2. There should be a 10 minute delay from the END of contrast injection to the start of the 3DT1 Post sequence
Sequence Weighting Change Parameters? Change # slices? Coverage/ Angulation Notes
AX POST FLAIR NO NO To AC-PC Line
AX POST 3DT1 NO NO To AC-PC Line Start this sequence 10 minutes AFTER THE END of the contrast injection