Publications | Lund Lab

Selected publications

Quantifying Leukocyte Egress via Lymphatic Vessels from Murine Skin and Tumors.
Steele, M. M., Churchill, M. J., Breazeale, A. P., Lane, R. S., Nelson, N. A., Lund, A. W. Quantifying Leukocyte Egress via Lymphatic Vessels from Murine Skin and Tumors. J. Vis. Exp. (143), e58704, doi:10.3791/58704 (2019).

IFNγ-activated dermal lymphatic vessels inhibit cytotoxic T cells in melanoma and inflamed skin.
Lane RS, Femel J, Breazeale AP, Loo CP, Thibault G, Kaempf A, Mori M, Tsujikawa T, Chang YH, Lund AW.
J Exp Med. 2018 Oct 31. pii: jem.20180654. doi: 10.1084/jem.20180654. [Epub ahead of print]
PMID:30381467

Toward Minimal Residual Disease-Directed Therapy in Melanoma.
Rambow F, Rogiers A, Marin-Bejar O, Aibar S, Femel J, Dewaele M, Karras P, Brown D, Chang YH, Debiec-Rychter M, Adriaens C, Radaelli E, Wolter P, Bechter O, Dummer R, Levesque M, Piris A, Frederick DT, Boland G, Flaherty KT, van den Oord J, Voet T, Aerts S, Lund AW, Marine JC.
Cell. 2018 Aug 9;174(4):843-855.e19. doi: 10.1016/j.cell.2018.06.025. Epub 2018 Jul 12.
PMID: 30017245

Characterization of dural sinus-associated lymphatic vasculature in human Alzheimer's dementia subjects.
Goodman JR, Adham ZO, Woltjer RL, Lund AW, Iliff JJ.
Brain Behav Immun. 2018 Oct;73:34-40. doi: 10.1016/j.bbi.2018.07.020. Epub 2018 Jul 25.
PMID:30055243

Non-Hematopoietic Control of Peripheral Tissue T cell Responses: Implications for Solid Tumors
Lane RS and Lund AW
Front. Immunol doi: 10.3389/fimmu.2018.02662

Lymphatic vessels balance viral dissemination and immune activation following cutaneous viral infection.
Loo, C.P., Nelson, N.A., Lane, R.S., Booth, J.L., Loprinzi Hardin, S.C., Thomas, A., Slifka, M.K., Nolz, J.C., Lund, A.W.
2017. Cell Reports Sept 20(13), p3176-3187.

Tumor lymphangiogenesis promotes T cell infiltration and potentiates immunotherapy in melanoma.
Fankhauser, M., Broggi, M.A.S., Potin, L., Bordry, N., Jeanbart, L., Lund, AW., Da Costa, E., Hauert, S., Rincon, M., Tremblay, C., Cabellow, E., Homicsko, K., Michielin, O., Hanahan, D., Speiser, D.E., and Swartz, M.A.
STM. 2017 Sep 13; 9(401): eaa1472.

Re-Thinking Lymphatic Vessels and Anti-Tumor Immunity.
Lund, A.W.
TRENDs in Cancer. 2016 Sept 24. doi:10.1016/j.trecan.2016.09.005.

Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
Lund AW, Wagner M, Fankhauser M, Steinskog ES, Broggi MA, Spranger S, Gajewski TF, Alitalo K, Eikesdal HP, Wiig H, Swartz MA.
J Clin Invest. 2016 Sep 1; 126(9):3389-402.

Non-invasive single-cell biomechanical analysis using live-imaging datasets.
Pearson YE, Lund AW, Lin AW, Ng CP, Alsuwaidi A, Azzeh S, Gater DL, Teo JC.
J Cell Sci. 2016 Sep1; 129(17):3351-64

Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer.
Lund AW, Medler TR, Leachman SA, Coussens LM.
Cancer Discov. 2016 Jan; 6(1):22-35

Steady-state antigen scavenging, cross-presentation and CD8+ T cell priming: a new role for lymphatic endothelial cells.
Hirosue, S., Vokali, E., Raghavan, V., Rincon-Restrepo, M., Lund, A.W.,et al.
J Immunol. 2014 Jun 1;192(11):5002-11

Targeting the tumor draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response.
Thomas S.N., Vokali, E., Lund, A.W., Hubbell, J.A., Swartz, M.A.
Biomaterials. 2014 Jan;35(2):814-24.

Long-term intravital imaging of tissue matrix components with epifluorescence and two-photon microscopy.
Guc E., Fankhauser, M., Lund, A.W., Swartz, M.A., Kilarski, W.W.
JOVE accepted October 2013.

Intravital Immunofluorescence for Visualization of the Microcirculatory and Immune Microenvironment in the Mouse Ear Dermis.
Kilarski, W.W., Guc, E., Teo, J.C.M., Oliver, S.R., Lund, A.W. and Swartz, M.A.
PLoS One. 2013;8(2).
Image (Kilarski and Lund) using technique selected for cover image of Nature Technology Feature, Marx, V. Tracking Metastasis and Tricking Cancer.
Nature 2013 Feb 494: 131-136.

VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics.
Lund, A.W., Duraes, F.V., Hirosue, S., Raghavan, V.R.,Thomas, S.N., Nembrini, C., Issa, A., Hugues, S., Swartz, M.A.
Cell Reports. 2012 Feb 1(3):191-199.

Lymphatic and Interstitial Flow in the Tumor Microenvironment: Linking Tumor Mechanobiology with Lymph Node Immunity.
M.A. Swartz and Lund, A.W.
Nat Rev Cancer. 2012 Feb 24;12(3):201-9.