Publications
Selected publications
Ruhland, M.K.*, Roberts, E.W.*, Cai, E., Mujal, A.M., Marchuk, K., Beppler, C., Nam, D., Serwas, N., Binnewies, M., Krummel, M.F., (2020). Visualizing synaptic transfer of tumor antigens among dendritic cells. Cancer Cell, 37(6):786-799.e5. doi: 10.1016/j.ccell.2020.05.002. *Authors contributed equally
Binnewies, M.*, Mujal, A.M.*, Pollack, J.L., Combes, A.J., Hardison, E.A., Barry, K.C., Tsui, J. Ruhland, M.K., Kersten, K., Abushawish, M.A., Spasic, M., Giurintano, J.P., Chan, V., Daud, A.I., Ha, P., Ye, C.J., Roberts, E.W., Krummel, M.F. (2019). Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T cell Immunity. Cell. 177(3):556-571.e16. doi: 10.1016/j.cell.2019.02.005 *Authors contributed equally
Ruhland M.K., Loza, A.J., Capietto, A.H., Luo, X., Knolhoff, B.L., Flanagan, K.C., Belt, B.A., Alspach, E., Leahy, K., Luo, J., Schaffer, A., Edwards, J.R., Longmore, G., Faccio, R., DeNardo, D.G., Stewart S.A., (2016). Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis. Nature Communications. 7(11762). doi:10.1038/ncomms11762
Ruhland M.K., Coussens, L.M., Stewart, S.A. (2016). Senescence and cancer: An evolving inflammatory paradox. Biochim Biophys Acta. 1865(1):14-22. doi: 10.1016/j.bbcan.2015.10.001
Luo, X.*, Fu, Y.*, Loza, A.J., Murali, B., Leahy, K., Ruhland, M.K., Gang, M., Su, X., Zamani, A., Shi, Y., Lavine, K., Ornitz, D.M., Weilbaecher, K.N., Long, F., Novack, D.V., Faccio, R., Longmore, G., Stewart, S.A. (2016). Stromal-initiated changes in the bone promote metastatic niche development. Cell Reports. 14(1):82- 92. doi: 10.1016/j.celrep.2015.12.016
Alspach, E., Flanagan K.C., Luo X., Ruhland M.K., Huang H., Pazolli E., Donlin M.J., Marsh T., Piwnica- Worms D., Monahan J., Novack D.V., McAllister S.S., Stewart S.A. (2014). p38MAPK plays a crucial role in stromal mediated tumorigenesis. Cancer Discovery. 4(6):716-29. doi: 10.1158/2159-8290.CD-13-0743
Luo, X., Ruhland, M.K., Pazolli, E., Lind, A.C., Stewart, S.A. (2011). Osteopontin stimulates preneoplastic cellular proliferation through activation of the MAPK pathway. Molecular Cancer Research. 9(8):1018-1029. doi: 10.1158/1541-7786.MCR-10-0472