Welcome
The Vaccine and Gene Therapy Institute at Oregon Health & Science University has assembled a multidisciplinary team of scientists to respond to serious viral disease threats, including AIDS, chronic viral infection-associated diseases, newly emerging viral diseases and infectious diseases of the elderly. Our programs are intended to span the continuum between basic and clinical science, in which discoveries are rapidly advanced from the level of molecular and cellular biology through animal models and ultimately into clinical testing. Learn more
VGTI Seminar Series
Recent publications
PLoS Pathog. November 11, 2024
A model of lymphocryptovirus-associated post-transplant lymphoproliferative disorder in immunosuppressed Mauritian cynomolgus macaques
J Infect Dis. October, 28, 2024
Impact of Dolutegravir plus Lamivudine as First-Line Antiretroviral Treatment on HIV-1 Reservoir and Inflammatory Markers in Peripheral Blood
Curr Opin HIV AIDS. October 22, 2024
Stem cell transplantation and allogeneic immunity: post treatment control or HIV cure?
Cancers (Basel). October 19, 2024
Functional Targets for Epstein-Barr Virus BART MicroRNAs in B Cel Lymphomas
Front Immunol. October 15, 2024
Functional genomic analysis of the 68-1 RhCMV-Mycobacteria tuberculosis vaccine reveals an IL-15 response signature that is conserved with vector attenuation
Proc Natl Acad Sci USA. October 15, 2024
Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
Sci Immunol. October 11, 2024
Human cytomegalovirus UL18 prevents priming of MHC-E- and MHC-II-restricted CD8+ T cells.
Microbiol Spectr. September 30, 2024
Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaques
Mabs. September 26, 2024
FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques
BioDrugs. September 18, 2024
Chikungunya Virus Vaccines: A Review of IXCHIQ and PXVX0317 from Pre-Clinical Evaluation to Licensure
Nat Immunol. September 12, 2024
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption
mBio. September 6, 2024
Bystander monocytic cells drive infection-independent NLRP3 inflammasome response to SARS-CoV-2
Cell. September 5, 2024
Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5
Cell. September 5, 2024
Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype
Journal of Virology. August 2024
Regulation of the cell surface expression of classical and non-classical MHC proteins by the human cytomegalovirus UL40 and rhesus cytomegalovirus Rh67 proteins
J Virol. August 29, 2024
A nanobody interaction with SARS-COV-2 Spike allows the versatile targeting of lentivirus vectors
JCI Insight. August 27, 2024
Immune perturbation following SHIV infection is greater in newborn macaques than in infants
PLoS Pathog. August 22, 2024
Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence
Science. August 9, 2024
Engineered deletions of HIV replicate conditionally to reduce disease in nonhuman primates
JCI Insight. August 8, 2024
Effect of metabolic status on response to SIV infection and antiretroviral therapy in nonhuman primates
Ways to Give
Donate to Vaccine and Gene Therapy Institute.
VGTI offers two options and account to consider when donating that serve differing purposes:
The VGTI Support Foundation Fund
Gifts to the VGTI Support Foundation Fund provides vital support that allows us find cures for life threatening infectious diseases. These funds help us to have necessary resources and create and conduct innovative infectious disease research studies, leading to the development of vaccines and cures.
The Jay Nelson Memorial Fund
Gifts to the Jay Nelson Memorial Fund supports providing education and learning opportunities for our current up and coming scientists with a focus on Herpesvirus.
Your Gift Brings Hope, Please support our mission in memory of Jay Nelson. Your generosity will help support education and learning opportunities for our current up and coming scientists with a focus on Herpesvirus. Click to Donate
The VGTI Support Foundation Fund
Donate to VGTI
Your gifts help provide vital resources to conduct innovative research and more.
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