Professor of Molecular and Medical Genetics, School of Medicine
Professor of Orthopaedics and Rehabilitation, School of Medicine
Publications
Selected publications
Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates.
Trofka A, Huang BL, Zhu J, Heinz WF, Magidson V, Shibata Y, Shi YB, Tarchini B, Stadler HS, Kabangu M, Al Haj Baddar NW, Voss SR, Mackem S.Curr Biol. 2021 Nov 22;31(22):4923-4934.e5. doi: 10.1016/j.cub.2021.09.010. Epub 2021 Oct
HOXA13 in etiology and oncogenic potential of Barrett's esophagus.
Janmaat VT, Nesteruk K, Spaander MCW, Verhaar AP, Yu B, Silva RA, Phillips WA, Magierowski M, van de Winkel A, Stadler HS, Sandoval-Guzmán T, van der Laan LJW, Kuipers EJ, Smits R, Bruno MJ, Fuhler GM, Clemons NJ, Peppelenbosch MP.Nat Commun. 2021 Jun 7;12(1):3354. doi: 10.1038/s41467-021-23641-8.
Meeting report on the NIDDK/AUA Workshop on Congenital Anomalies of External Genitalia: challenges and opportunities for translational research.Stadler HS, Peters CA, Sturm RM, Baker LA, Best CJM, Bird VY, Geller F, Hoshizaki DK, Knudsen TB, Norton JM, Romao RLP, Cohn MJ.J Pediatr Urol. 2020 Dec;16(6):791-804. doi: 10.1016/j.jpurol.2020.09.012. Epub 2020 Sep 16.
Encouraging cartilage production.Stadler HS. Elife. 2020 May 6;9:e57239. doi: 10.7554/eLife.57239.
The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13.
Bastida MF, Pérez-Gómez R, Trofka A, Zhu J, Rada-Iglesias A, Sheth R, Stadler HS, Mackem S, Ros MA.Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1090-1096. doi: 10.1073/pnas.1919470117. Epub 2020 Jan 2.
Development and functional characterization of a lncRNA-HIT conditional loss of function allele.
Carlson HL, Stadler HS.Genesis. 2020 Mar;58(3-4):e23351. doi: 10.1002/dvg.23351. Epub 2019 Dec 14.PMID: 31838787
Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13.
Sheth R, Barozzi I, Langlais D, Osterwalder M, Nemec S, Carlson HL, Stadler HS, Visel A, Drouin J, Kmita M.Cell Rep. 2016 Dec 13;17(11):2913-2926. doi: 10.1016/j.celrep.2016.11.039.
Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state.
Kherdjemil Y, Lalonde RL, Sheth R, Dumouchel A, de Martino G, Pineault KM, Wellik DM, Stadler HS, Akimenko MA, Kmita M.Nature. 2016 Nov 3;539(7627):89-92. doi: 10.1038/nature19813. Epub 2016 Oct 5.
LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes.
Carlson HL, Quinn JJ, Yang YW, Thornburg CK, Chang HY, Stadler HS.PLoS Genet. 2015 Dec 3;11(12):e1005680. doi: 10.1371/journal.pgen.1005680. eCollection 2015 Dec.
Musculoskeletal integration at the wrist underlies the modular development of limb tendons.
Huang AH, Riordan TJ, Pryce B, Weibel JL, Watson SS, Long F, Lefebvre V, Harfe BD, Stadler HS, Akiyama H, Tufa SF, Keene DR, Schweitzer R.Development. 2015 Jul 15;142(14):2431-41. doi: 10.1242/dev.122374. Epub 2015 Jun 10.