Chris Harrington, Ph.D. Publications

NCBI bibliography listing of publications: https://www.ncbi.nlm.nih.gov/myncbi/1xMz53gmsJkAn/bibliography/public/

Selected Publications:

RNA-seq from archival FFPE breast cancer samples: molecular pathway fidelity and novel discovery.
Pennock ND, Jindal S, Horton W, Sun D, Narasimhan J, Carbone L, Fei SS, Searles R, Harrington CA, Burchard J, Weinmann S, Schedin P, Xia Z.
BMC Med Genomics. 2019 Dec 19;12(1):195. doi: 10.1186/s12920-019-0643-z.

Validation of MicroRNA Biomarkers for Alzheimer's Disease in Human Cerebrospinal Fluid.
Wiedrick JT, Phillips JI, Lusardi TA, McFarland TJ, Lind B, Sandau US, Harrington CA, Lapidus JA, Galasko DR, Quinn JF, Saugstad JA.
J Alzheimers Dis. 2019;67(3):875-891. doi: 10.3233/JAD-180539.

microRNA-130a suppresses breast cancer cell migration and invasion by targeting FOSL1 and upregulating ZO-1.
Chen X, Zhao M, Huang J, Li Y, Wang S, Harrington CA, Qian DZ, Sun XX, Dai MS.
J Cell Biochem. 2018 Jun;119(6):4945-4956. doi: 10.1002/jcb.26739. Epub 2018 Mar 9.

Gene Expression Profiling and Heterogeneity of Nonspecific Orbital Inflammation Affecting the Lacrimal Gland.
Rosenbaum JT, Choi D, Harrington CA, Wilson DJ, Grossniklaus HE, Sibley CH, Salek SS, Ng JD, Dailey RA, Steele EA, Hayek B, Craven CM, Edward DP, Maktabi AMY, Al Hussain H, White VA, Dolman PJ, Czyz CN, Foster JA, Harris GJ, Bee YS, Tse DT, et al.
JAMA Ophthalmol. 2017 Nov 1;135(11):1156-1162. doi: 10.1001/jamaophthalmol.2017.3458.

Analysis of extracellular RNA in cerebrospinal fluid.
Saugstad JA, Lusardi TA, Van Keuren-Jensen KR, Phillips JI, Lind B, Harrington CA, McFarland TJ, Courtright AL, Reiman RA, Yeri AS, Kalani MYS, Adelson PD, Arango J, Nolan JP, Duggan E, Messer K, Akers JC, Galasko DR, Quinn JF, Carter BS, Hochberg FH.
J Extracell Vesicles. 2017 May 24;6(1):1317577. doi: 10.1080/20013078.2017.1317577. eCollection 2017.

MicroRNAs in Human Cerebrospinal Fluid as Biomarkers for Alzheimer's Disease.
Lusardi TA, Phillips JI, Wiedrick JT, Harrington CA, Lind B, Lapidus JA, Quinn JF, Saugstad JA.
J Alzheimers Dis. 2017;55(3):1223-1233.

MicroRNA Signatures of Colonic Polyps on Screening and Histology.
Tsikitis VL, Potter A, Mori M, Buckmeier JA, Preece CR, Harrington CA, Bartley AN, Bhattacharyya AK, Hamilton SR, Lance MP, Thompson PA.
Cancer Prev Res (Phila). 2016 Dec;9(12):942-949. Epub 2016 Sep 22.

AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB.
Hornick NI, Doron B, Abdelhamed S, Huan J, Harrington CA, Shen R, Cambronne XA, Chakkaramakkil Verghese S, Kurre P.
Sci Signal. 2016 Sep 6;9(444):ra88. doi: 10.1126/scisignal.aaf2797.

Fibrosis, gene expression and orbital inflammatory disease.
Rosenbaum JT, Choi D, Wilson DJ, Grossniklaus HE, Harrington CA, Dailey RA, Ng JD, Steele EA, Czyz CN, Foster JA, Tse D,
Alabiad C, Dubovy S, Parekh P, Harris GJ, Kazim M, Patel P, White V, Dolman P, Edward DP, Alkatan H, Al Hussain H, et al.
Br J Ophthalmol. 2015 Oct;99(10):1424-9. doi: 10.1136/bjophthalmol-2015-306614. Epub 2015 Jun 2.

Parallel Gene Expression Changes in Sarcoidosis Involving the Lacrimal Gland, Orbital Tissue, or Blood.
Rosenbaum JT, Choi D, Wilson DJ, Grossniklaus HE, Harrington CA, Sibley CH, Dailey RA, Ng JD, Steele EA, Czyz CN, Foster JA,Tse D, Alabiad C, Dubovy S, Parekh P, Harris GJ, Kazim M, Patel P, White V, Dolman P, Korn BS, Kikkawa D, et al.
JAMA Ophthalmol. 2015 Jul;133(7):770-7. doi: 10.1001/jamaophthalmol.2015.0726.

Molecular diagnosis of orbital inflammatory disease.
Rosenbaum JT, Choi D, Wilson DJ, Grossniklaus HE, Sibley CH, Harrington CA, Planck SR; Orbital Disease Consortium..
Exp Mol Pathol. 2015 Apr;98(2):225-9. doi: 10.1016/j.yexmp.2015.01.009. Epub 2015 Jan 14.

Computational detection of alternative exon usage.
Laderas TG, Walter NA, Mooney M, Vartanian K, Darakjian P, Buck K, Harrington CA, Belknap J, Hitzemann R, McWeeney SK.
Front Neurosci. 2011 May 13;5:69. doi: 10.3389/fnins.2011.00069. eCollection 2011.

Expression profiling of the ovarian surface kinome reveals candidate genes for early neoplastic changes.
Pejovic T, Pande NT, Mori M, Mhawech-Fauceglia P, Harrington C, Mongoue-Tchokote S, Dim D, Andrews C, Beck A, Tarumi Y, Djilas J, Cappuccini F, Caballero O, Huang J, Levy S, Tsiamouri A, Cain J, Bagby GC, Strausberg RL, Simpson AJ, Odunsi KO.
Transl Oncol. 2009 Dec;2(4):341-9.

A gene expression signature of CD34+ cells to predict major cytogenetic response in chronic-phase chronic myeloid leukemia patients treated with imatinib.
McWeeney SK, Pemberton LC, Loriaux MM, Vartanian K, Willis SG, Yochum G, Wilmot B, Turpaz Y, Pillai R, Druker BJ, Snead JL, MacPartlin M, O'Brien SG, Melo JV, Lange T, Harrington CA, Deininger MW.
Blood. 2010 Jan 14;115(2):315-25. doi: 10.1182/blood-2009-03-210732. Epub 2009 Oct 16.

Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: a critical role for IRF3.
Marsh B, Stevens SL, Packard AE, Gopalan B, Hunter B, Leung PY, Harrington CA, Stenzel-Poore MP.
J Neurosci. 2009 Aug 5;29(31):9839-49. doi: 10.1523/JNEUROSCI.2496-09.2009.

Gene expression profiling of whole blood: comparison of target preparation methods for accurate and reproducible microarray analysis.
Vartanian K, Slottke R, Johnstone T, Casale A, Planck SR, Choi D, Smith JR, Rosenbaum JT, Harrington CA.
BMC Genomics. 2009 Jan 5;10:2. doi: 10.1186/1471-2164-10-2.

Randomization in laboratory procedure is key to obtaining reproducible microarray results.
Yang H, Harrington CA, Vartanian K, Coldren CD, Hall R, Churchill GA.
PLoS One. 2008;3(11):e3724. doi: 10.1371/journal.pone.0003724. Epub 2008 Nov 14.

On the integration of alcohol-related quantitative trait loci and gene expression analyses.
Hitzemann R, Reed C, Malmanger B, Lawler M, Hitzemann B, Cunningham B, McWeeney S, Belknap J, Harrington C, Buck K, Phillips T, Crabbe J.
Alcohol Clin Exp Res. 2004 Oct;28(10):1437-48. Erratum in: Alcohol Clin Exp Res. 2004 Dec;28(12):1930.

Effect of ischaemic preconditioning on genomic response to cerebral ischaemia: similarity to neuroprotective strategies in
hibernation and hypoxia-tolerant states.

Stenzel-Poore MP, Stevens SL, Xiong Z, Lessov NS, Harrington CA, Mori M, Meller R, Rosenzweig HL, Tobar E, Shaw TE, Chu X, Simon RP.
Lancet. 2003 Sep 27;362(9389):1028-37.

Analysis of high density expression microarrays with signed-rank call algorithms.
Liu WM, Mei R, Di X, Ryder TB, Hubbell E, Dee S, Webster TA, Harrington CA, Ho MH, Baid J, Smeekens SP.
Bioinformatics. 2002 Dec;18(12):1593-9.

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