HCMV UL8 interaction with β-catenin and DVL2 regulates viral reactivation in CD34⁺ hematopoietic progenitor cells.
Dirck A, Diggins NL, Crawford LB, Perez WD, Parkins CJ, Struthers HH, Turner R, Pham AH, Mitchell J, Papen CR, Malouli D, Hancock MH, Caposio P.J Virol. 2023 Oct 31;97(10):e0124123. doi: 10.1128/jvi.01241-23. Epub 2023 Sep 29.PMID: 37772824 Free PMC article.

Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation.
Medica S, Crawford LB, Denton M, Min CK, Jones TA, Alexander T, Parkins CJ, Diggins NL, Streblow GJ, Mayo AT, Kreklywich CN, Smith P, Jeng S, McWeeney S, Hancock MH, Yurochko A, Cohen MS, Caposio P, Streblow DN.PLoS Pathog. 2023 Oct 2;19(10):e1011682. doi: 10.1371/journal.ppat.1011682. eCollection 2023 Oct.PMID: 37782657 Free PMC article.

Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection.
Zarrella K, Longmire P, Zeltzer S, Collins-McMillen D, Hancock M, Buehler J, Reitsma JM, Terhune SS, Nelson JA, Goodrum F.PLoS Pathog. 2023 Jun 8;19(6):e1011185. doi: 10.1371/journal.ppat.1011185. eCollection 2023 Jun.PMID: 37289831 Free PMC article.

Viral miRNA regulation of host gene expression.
Diggins NL, Hancock MH.Semin Cell Dev Biol. 2023 Sep 15;146:2-19. doi: 10.1016/j.semcdb.2022.11.007. Epub 2022 Nov 30.PMID: 36463091 Review.

mRNA vaccine against fibroblast activation protein ameliorates murine models of inflammatory arthritis.
Zhang X, Jozic A, Song P, Xu Q, Shi X, Wang H, Bishop L, Struthers HM, Rutledge J, Chen S, Xu F, Hancock MH, Zhu D, Sahay G, Chu CQ.Rheumatol Immunol Res. 2023 Jul 22;4(2):90-97. doi: 10.2478/rir-2023-0013. eCollection 2023 Jun.PMID: 37818347 Free PMC article.

Myeloid cell tropism enables MHC-E-restricted CD8⁺ T cell priming and vaccine efficacy by the RhCMV/SIV vaccine.
Hansen SG, Hancock MH, Malouli D, Marshall EE, Hughes CM, Randall KT, Morrow D, Ford JC, Gilbride RM, Selseth AN, Trethewy RE, Bishop LM, Oswald K, Shoemaker R, Berkemeier B, Bosche WJ, Hull M, Silipino L, Nekorchuk M, Busman-Sahay K, Estes JD, Axthelm MK, Smedley J, Shao D, Edlefsen PT, Lifson JD, Früh K, Nelson JA, Picker LJ.Sci Immunol. 2022 Jun 24;7(72):eabn9301. doi: 10.1126/sciimmunol.abn9301. Epub 2022 Jun 17.PMID: 35714200 Free PMC article.

Advances in Model Systems for Human Cytomegalovirus Latency and Reactivation.
Crawford LB, Diggins NL, Caposio P, Hancock MH.mBio. 2022 Feb 22;13(1):e0172421. doi: 10.1128/mbio.01724-21. Epub 2022 Jan 11.PMID: 35012351 Free PMC article. 

Human cytomegalovirus blocks canonical TGFβ signaling during lytic infection to limit induction of type I interferons.
Pham AH, Mitchell J, Botto S, Pryke KM, DeFilippis VR, Hancock MH.PLoS Pathog. 2021 Aug 19;17(8):e1009380. doi: 10.1371/journal.ppat.1009380. eCollection 2021 Aug.PMID: 34411201 Free PMC article.

Human Cytomegalovirus Host Interactions: EGFR and Host Cell Signaling Is a Point of Convergence Between Viral Infection and Functional Changes in Infected Cells.
Lee BJ, Min CK, Hancock M, Streblow DN, Caposio P, Goodrum FD, Yurochko AD.Front Microbiol. 2021 May 7;12:660901. doi: 10.3389/fmicb.2021.660901. eCollection 2021.PMID: 34025614 Free PMC article.

Human Cytomegalovirus miR-US25-1 Targets the GTPase RhoA To Inhibit CD34⁺ Hematopoietic Progenitor Cell Proliferation To Maintain the Latent Viral Genome.
Diggins NL, Crawford LB, Hancock MH, Mitchell J, Nelson JA.mBio. 2021 Apr 6;12(2):e00621-21. doi: 10.1128/mBio.00621-21.PMID: 33824207 Free PMC article.

Cytomegaloviral determinants of CD8⁺ T cell programming and RhCMV/SIV vaccine efficacy.
Malouli D, Hansen SG, Hancock MH, Hughes CM, Ford JC, Gilbride RM, Ventura AB, Morrow D, Randall KT, Taher H, Uebelhoer LS, McArdle MR, Papen CR, Espinosa Trethewy R, Oswald K, Shoemaker R, Berkemeier B, Bosche WJ, Hull M, Greene JM, Axthelm MK, Shao J, Edlefsen PT, Grey F, Nelson JA, Lifson JD, Streblow D, Sacha JB, Früh K, Picker LJ.Sci Immunol. 2021 Mar 25;6(57):eabg5413. doi: 10.1126/sciimmunol.abg5413.PMID: 33766849 Free PMC article.

Regulation of Latency and Reactivation by Human Cytomegalovirus miRNAs.
Diggins NL, Skalsky RL, Hancock MH.Pathogens. 2021 Feb 13;10(2):200. doi: 10.3390/pathogens10020200.PMID: 33668486 Free PMC article.

Hematopoietic cell-mediated dissemination of murine cytomegalovirus is regulated by NK cells and immune evasion.
Zhang S, Springer LE, Rao HZ, Espinosa Trethewy RG, Bishop LM, Hancock MH, Grey F, Snyder CM.PLoS Pathog. 2021 Jan 28;17(1):e1009255. doi: 10.1371/journal.ppat.1009255. eCollection 2021 Jan.PMID: 33508041 Free PMC article.

CD34⁺ Hematopoietic Progenitor Cell Subsets Exhibit Differential Ability To Maintain Human Cytomegalovirus Latency and Persistence.
Crawford LB, Hancock MH, Struthers HM, Streblow DN, Yurochko AD, Caposio P, Goodrum FD, Nelson JA.J Virol. 2021 Jan 13;95(3):e02105-20. doi: 10.1128/JVI.02105-20. Print 2021 Jan 13.PMID: 33177198 Free PMC article.

Human Cytomegalovirus UL7, miR-US5-1, and miR-UL112-3p Inactivation of FOXO3a Protects CD34⁺ Hematopoietic Progenitor Cells from Apoptosis.
Hancock MH, Crawford LB, Perez W, Struthers HM, Mitchell J, Caposio P.mSphere. 2021 Jan 6;6(1):e00986-20. doi: 10.1128/mSphere.00986-20.PMID: 33408225 Free PMC article.

Techniques for Characterizing Cytomegalovirus-Encoded miRNAs.
Diggins NL, Crawford LB, Struthers HM, Hook LM, Landais I, Skalsky RL, Hancock MH.Methods Mol Biol. 2021;2244:301-342. doi: 10.1007/978-1-0716-1111-1_16.PMID: 33555594

Human Cytomegalovirus miR-US5-2 Downregulation of GAB1 Regulates Cellular Proliferation and UL138 Expression through Modulation of Epidermal Growth Factor Receptor Signaling Pathways.
Hancock MH, Mitchell J, Goodrum FD, Nelson JA.mSphere. 2020 Aug 5;5(4):e00582-20. doi: 10.1128/mSphere.00582-20.PMID: 3275933 Free PMC article.

Human Cytomegalovirus miRNAs Regulate TGF-β to Mediate Myelosuppression while Maintaining Viral Latency in CD34⁺ Hematopoietic Progenitor Cells.
Hancock MH, Crawford LB, Pham AH, Mitchell J, Struthers HM, Yurochko AD, Caposio P, Nelson JA.Cell Host Microbe. 2020 Jan 8;27(1):104-114.e4. doi: 10.1016/j.chom.2019.11.013. Epub 2019 Dec 19.PMID: 31866424 Free PMC article.

Human Cytomegalovirus miRNAs Regulate TGF-β to Mediate Myelosuppression while Maintaining Viral Latency in CD34⁺ Hematopoietic Progenitor Cells.
Hancock MH, Crawford LB, Pham AH, Mitchell J, Struthers HM, Yurochko AD, Caposio P, Nelson JA.Cell Host Microbe. 2020 Jan 8;27(1):104-114.e4. doi: 10.1016/j.chom.2019.11.013. Epub 2019 Dec 19.PMID: 31866424 Free PMC article.

Human Cytomegalovirus US28 Ligand Binding Activity Is Required for Latency in CD34⁺ Hematopoietic Progenitor Cells and Humanized NSG Mice.
Crawford LB, Caposio P, Kreklywich C, Pham AH, Hancock MH, Jones TA, Smith PP, Yurochko AD, Nelson JA, Streblow DN.mBio. 2019 Aug 20;10(4):e01889-19. doi: 10.1128/mBio.01889-19.PMID: 31431555 Free PMC article.

HCMV miRNA Targets Reveal Important Cellular Pathways for Viral Replication, Latency, and Reactivation.
Diggins NL, Hancock MH.Noncoding RNA. 2018 Oct 22;4(4):29. doi: 10.3390/ncrna4040029.PMID: 30360396 Free PMC article. 

Roles of Non-coding RNAs During Herpesvirus Infection.
Hancock MH, Skalsky RL.Curr Top Microbiol Immunol. 2018;419:243-280. doi: 10.1007/82_2017_31.PMID: 28674945 Free PMC article. 

Modulation of the NFκb Signalling Pathway by Human Cytomegalovirus.
Hancock MH, Nelson JA.Virology (Hyderabad). 2017 Aug;1(1):104. Epub 2017 Jul 31.PMID: 29082387 

Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-κB-Activating Factors through Direct Downregulation of IKKα and IKKβ.
Hancock MH, Hook LM, Mitchell J, Nelson JA.mBio. 2017 Mar 7;8(2):e00109-17. doi: 10.1128/mBio.00109-17.PMID: 28270578 Free PMC article.

Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques.
Burwitz BJ, Malouli D, Bimber BN, Reed JS, Ventura AB, Hancock MH, Uebelhoer LS, Bhusari A, Hammond KB, Espinosa Trethewy RG, Klug A, Legasse AW, Axthelm MK, Nelson JA, Park BS, Streblow DN, Hansen SG, Picker LJ, Früh K, Sacha JB.PLoS Pathog. 2016 Nov 9;12(11):e1006014. doi: 10.1371/journal.ppat.1006014. eCollection 2016 Nov.PMID: 27829026 Free PMC article.

Techniques for characterizing cytomegalovirus-encoded miRNAs.
Hook LM, Landais I, Hancock MH, Nelson JA.Methods Mol Biol. 2014;1119:239-65. doi: 10.1007/978-1-62703-788-4_14.PMID: 24639227

Rhesus cytomegalovirus encodes seventeen microRNAs that are differentially expressed in vitro and in vivo.
Hancock MH, Tirabassi RS, Nelson JA.Virology. 2012 Apr 10;425(2):133-42. doi: 10.1016/j.virol.2012.01.009. Epub 2012 Feb 2.PMID: 22305624 Free PMC article.