Lab publications

  • Murphy Schafer AR, Smith JL, Pryke KM, DeFilippis VR, Hirsch AJ. The E3 Ubiquitin Ligase SIAH1 Targets MyD88 for Proteasomal Degradation During Dengue Virus Infection. Front Microbiol. 2020 Feb 14;11:24. doi: 10.3389/fmicb.2020.00024. PMID: 32117091; PMCID: PMC7033647.
     
  • Smith JL, Hirsch AJ. Analysis of Serum Anti-Zika Virus Antibodies by Focus Reduction Neutralization Test. Methods Mol Biol. 2020;2142:73-80. doi: 10.1007/978-1-0716-0581-3_6. PMID: 32367359.
  • Smith JL, Sheridan K, Parkins CJ, Frueh L, Jemison AL, Strode K, Dow G, Nilsen A, Hirsch AJ. Characterization and structure-activity relationship analysis of a class of antiviral compounds that directly bind dengue virus capsid protein and are incorporated into virions. Antiviral Res. 2018 Jul;155:12-19. doi: 10.1016/j.antiviral.2018.04.019. Epub 2018 Apr 27. PMID: 29709563; PMCID: PMC9627977.
     
  • Hirsch AJ, Roberts VHJ, Grigsby PL, Haese N, Schabel MC, Wang X, Lo JO, Liu Z, Kroenke CD, Smith JL, Kelleher M, Broeckel R, Kreklywich CN, Parkins CJ, Denton M, Smith P, DeFilippis V, Messer W, Nelson JA, Hennebold JD, Grafe M, Colgin L, Lewis A, Ducore R, Swanson T, Legasse AW, Axthelm MK, MacAllister R, Moses AV, Morgan TK, Frias AE, Streblow DN. Zika virus infection in pregnant rhesus macaques causes placental dysfunction and immunopathology. Nat Commun. 2018 Jan 17;9(1):263. doi: 10.1038/s41467-017-02499-9. PMID: 29343712; PMCID: PMC5772047.
     
  • Hirsch AJ, Smith JL, Haese NN, Broeckel RM, Parkins CJ, Kreklywich C, DeFilippis VR, Denton M, Smith PP, Messer WB, Colgin LM, Ducore RM, Grigsby PL, Hennebold JD, Swanson T, Legasse AW, Axthelm MK, MacAllister R, Wiley CA, Nelson JA, Streblow DN. Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues. PLoS Pathog. 2017 Mar 9;13(3):e1006219. doi: 10.1371/journal.ppat.1006219. Erratum in: PLoS Pathog. 2017 Apr 5;13(4):e1006317. PMID: 28278237; PMCID: PMC5344528.
     
  • Smith JL, Jeng S, McWeeney SK, Hirsch AJ. A MicroRNA Screen Identifies the Wnt Signaling Pathway as a Regulator of the Interferon Response during Flavivirus Infection. J Virol. 2017 Mar 29;91(8):e02388-16. doi: 10.1128/JVI.02388-16. PMID: 28148804; PMCID: PMC5375670.