Blackburn Lab

Advanced spectroscopies

Our lab focuses on the structure and function of oxidase and oxygenase metalloenzymes, particularly copper monooxygenases. We specialize in coordination chemistry and the biochemistry of copper, with particular focus in enzymes which influence neuroendocrine function, pathogen virulence, and cancer. Our biophysical areas of expertise include X-ray absorption spectroscopies (XAS, EXAFS, X-ray crystallography), spectroscopy (EPR, UV-Vis, fluorescence, FTIR), and rapid kinetics (RFQ, stopped-flow, quench-flow microvolume).