Neuronal signaling encompasses much of what neurons and glia do - from membrane receptors to intracellular signaling cascades and on to gene expression in the nucleus. Studies of neuronal signaling cross subdisciplinary boundaries from cells and synapses to systems and behavior and disruptions of signaling pathways in disease. The growing interest of stem cell biology and cell-based therapies in biomedicine is as important in neuroscience as it is in other disciplines such as cancer biology. NGP faculty members interested in neuronal signaling are actively engaged in this full spectrum using approaches from biochemistry to structural biology as well as physiology and imaging. Some of the molecules under study include kinases, phosphatases, G protein coupled receptor signaling networks, cyclic nucleotides, growth factors to name a few.

To learn more about the work of NGP investigators in this area, click on the links below.