Publications
Selected publications
Case 35-2023: A 38-Year-Old Woman with Waxing and Waning Pulmonary Nodules.
McCannon JB, Shepard JO, Wong AK, Thomas MF, and Helland TF. Case 35-2023: A 38-year-old woman with waxing and waning pulmonary nodules. NEJM. 389 (20): 1902-11 (2023). PMID 37966289
Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor.
Blum S*, Zlotoff D*, Smith NP*, Kernin I*, Ramesh S, Zubiri L, Caplin J, Tirard A, Sen P, Song Y, Barth J, Slowikowski K, Nasrallah M, Tantivit J , Manakongtreecheep K, McGuire J, Pinto C, McLoughlin D, Jackson M, Chan P, Lawless A, Sharova T, Nieman L, Gainor J, Juric D, Mino-Kenudsen M, Sullivan R, Boland G, Stone J, Thomas MF†, Neilan T†, Reynolds KL†, and Villani AC†. Immune Responses in Checkpoint Myocarditis Across Heart, Blood, and Tumor. *Equal contribution, †co-senior authors. bioRxiv DOI: 10.1101/2023.09.15.557794.
Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans.
Guo L, Salian S, X J, Rath N, Rousseau J, Kim Hyunyun, Ehresmann S, Moosa S, Nakagawa N, Kuroda H, Clayton-Smith J, Wang J, Wang Z, Banka S, Jackson A, Zhang Y, Wei Z, Hüning I, Brunet T, Ohashi H, Thomas MF, Bupp C, Miyake N, Matsumoto N, Mendoza-Londono, Costain G, Hahn G, Donato N, Yigit G, Yamada T, Nichimura G, Ansel KM, Wollnik B, Angelis M, Mégarbané A, Rosenfeld JA, Heissmeyer V, Ikegawa, and Campeau PM. Am J Hum Genet. 110(7): 1068-1085 (2023). PMCID: PMC10357479
Altered interactions between circulating and tissue-resident CD8 T cells with the colonic mucosa define colitis associated with immune checkpoint inhibitors.
Thomas MF*, Slowikowski K*, Manakongtreecheep K, Sen P, Tantivit J, Nasrallah M, Smith NP, Ramesh S, Zubiri L, Tirard A, Arnold BY, Nieman LT, Chen JH, Eisenhaure T, Pelka K, Xu KH, Jorgi V, Pinto C, Sharova T, Glasser R, Chan P, Sullivan RJ, Khalili H, Juric D, Boland G, Dougan M, Hacohen N, Reynolds KL, Li B, and Villani AC. bioRxiv doi: 10.1101/2021.09.17.460868. *Equal contribution
Effect of a Multidisciplinary Severe Immunotherapy Complication Service on Outcomes for Patients Receiving Immune Checkpoint Inhibitor Therapy for Cancer.
Zubiri L, Molina G, Mooradian MJ, Cohen J, Durbin S, Petrillo L, Boland G, Juric D, Dougan M, Thomas MF, Faje AT, Rengarajan M, Guidon AV, Chen ST, Okin D, Medoff BD, Nasrallah M, Kohler MJ, Schoenfeld SR, Karp Leaf RS, Sise ME, Neilan TG, Zlotoff DA, Farmer JR, Bardia A, Sullivan RJ, Blum S, Semenov YR, Villani AC, and Reynolds KL. The Journal for ImmunoTherapy of Cancer, Sep;9(9): e002886 (2021). PMID 34544895
Temporal Trends and Outcomes Among Patients Admitted for Immune-Related Adverse Events: A Single-Center Retrospective Cohort Study from 2011 to 2018.
Molina GE, Zubiri L, Cohen JV, Durbin SM, Petrillo L, Allen IM, Murciano-Goroff YR, Dougan M, Thomas MF, Faje AT, Rengarajan M, Guidon AC, Chen ST, Okin D, Medoff BD, Nasrallah M, Kohler MJ, Schoenfeld SR, Karp Leaf RS, Sise ME, Neilan TG, Zlotoff DA, Farmer JR, Mooradian MJ, Bardia A, Mai M, Sullivan RJ, Semenov YR, Villani AC, Reynolds KL. The Oncologist. 26(6): 514-522 (2021). PMID: 33655682
Diagnosis and Management of Hepatitis in Patients on Checkpoint Blockade.
Reynolds K, Thomas MF, Dougan M. The Oncologist, Sep; 23(9): 991-997 (2018). PMID 29853659
Eri1: A conserved enzyme at the crossroads of multiple RNA-processing pathways.
Thomas MF, L’Etoile N, and KM Ansel. Trends in Genetics, 30(7): 298-307 (2014). PMID: 24929628
Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function.
Thomas MF, Abdul–Wajid S, Panduro M, Babiarz JE, Rajaram M, Woodruff P, Lanier LL, Heissmeyer V and KM Ansel. Blood. 120(1): 130–142 (2012). PMID 22613798
MicroRNA–29 regulates T–box transcription factors and IFN–γ production in helper T cells.
Steiner DF, Thomas MF, Hu JK, Yang Z, Babiarz JE, Allen CD, Matloubian M, Blelloch R, and KM Ansel. Immunity. 35(2): 169–81 (2011). PMID 21820330
A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing.
Babiarz JE, Hsu R, Melton C, Thomas MF, Ullian EM and R Blelloch. RNA. 17(8): 1489–501 (2011). PMID 21712401
Construction of small RNA cDNA libraries for deep sequencing.
Thomas MF & KM Ansel. In Methods in Molecular Biology: MicroRNAs and the Immune System, Vol. 667, ed. Monticelli, S. Humana Press Inc. (2010). PMID 20827529
Cytotoxicity mediated by the Fas ligand (FasL)–activated apoptotic pathway in stem cells.
Mazar J, Thomas MF, Bezrukov L, Chanturia A, Pekkurnaz G, Yin S, Kuznetsov SA, Robey PG and J Zimmerberg. Journal of Biological Chemistry. 284(33): 22022–8 (2009). PMID 19531476