Lab publications
Varco-Merth BD, Brantley W, Marenco A, Duell DD, Fachko DN, Richardson B, Busman-Sahay K, Shao D, Flores W, Engelman K, Fukazawa Y, Wong SW, Skalsky RL, Smedley J, Axthelm MK, Lifson JD, Estes JD, Edlefsen PT, Picker LJ, Cameron CM, Henrich TJ, Okoye AA. Rapamycin limits CD4+ T cell proliferation in simian immunodeficiency virus-infected rhesus macaques on antiretroviral therapy. J Clin Invest. 2022 May 16;132(10):e156063. doi: 10.1172/JCI156063. PMID: 35316218; PMCID: PMC9106346.
Fachko DN, Chen Y, Skalsky RL. Epstein-Barr Virus miR-BHRF1-3 Targets the BZLF1 3'UTR and Regulates the Lytic Cycle. J Virol. 2022 Feb 23;96(4):e0149521. doi: 10.1128/JVI.01495-21.
Chen Y, Fachko DN, Ivanov NS, Skalsky RL. B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition. mSphere. 2021 Apr 14;6(2):e00093-21. doi: 10.1128/mSphere.00093-21. PMID: 33853871; PMCID: PMC8546685.
Bouvet M, Voigt S, Tagawa T, Albanese M, Chen YA, Chen Y, Fachko DN, Pich D, Göbel C, Skalsky RL, Hammerschmidt W. Multiple Viral microRNAs Regulate Interferon Release and Signaling Early during Infection with Epstein-Barr Virus. mBio. 2021 Mar 30;12(2):e03440-20. doi: 10.1128/mBio.03440-20. PMID: 33785626; PMCID: PMC8092300.
Okoye AA, DeGottardi MQ, Fukazawa Y, Vaidya M, Abana CO, Konfe AL, Fachko DN, Duell DM, Li H, Lum R, Gao L, Park BS, Skalsky RL, Lewis AD, Axthelm MK, Lifson JD, Wong SW, Picker LJ. Role of IL-15 Signaling in the Pathogenesis of Simian Immunodeficiency Virus Infection in Rhesus Macaques. J Immunol. 2019 Dec 1;203(11):2928-2943. doi: 10.4049/jimmunol.1900792. Epub 2019 Oct 25. PMID: 31653683; PMCID: PMC6864325.
Chen Y, Fachko D, Ivanov NS, Skinner CM, Skalsky RL. Epstein-Barr virus microRNAs regulate B cell receptor signal transduction and lytic reactivation. PLoS Pathog. 2019 Jan 7;15(1):e1007535. doi: 10.1371/journal.ppat.1007535. PMID: 30615681; PMCID: PMC6336353.
Skinner CM, Ivanov NS, Barr SA, Chen Y, Skalsky RL. An Epstein-Barr Virus MicroRNA Blocks Interleukin-1 (IL-1) Signaling by Targeting IL-1 Receptor 1. J Virol. 2017 Oct 13;91(21):e00530-17. doi: 10.1128/JVI.00530-17. PMID: 28794034; PMCID: PMC5640834.