Infectious Disease faculty lead Infection Prevention and Control (IPC) programs at OHSU Hospital and Clinics (Dr. John Townes, Medical Director, and Dr. Lynne Strasfeld, Associate Medical Director for Transplant Services), Hillsboro Medical Center (Dr. Holly Villamagna, Medical Director), and the VA Portland Health Care System which includes the hospital, nursing home, and surrounding clinics (Dr. Christopher Pfeiffer, Hospital Epidemiologist, and Dr. Monica Sikka, Associate Hospital Epidemiologist). IPC plays many roles, including but not limited to surveillance of healthcare-associated infections, outbreak management, development and implementation of IPC standard policies, and policies related to novel/emerging pathogens as they arise. The dynamic, ever-changing landscape of infectious diseases and the IPC challenges they pose, from Clostridioides difficile to influenza, multidrug-resistant pathogens, and COVID-19, highlights the pivotal role IPC plays in our healthcare system. Our IPC groups also serve the educational and research missions of an academic medical center, providing ID fellows with formal didactics, opportunities for hands-on participation in IPC activities, and opportunities for original research projects.