The Davis Lab focuses on developing new therapeutic approaches for aggressive pediatric, adolescent, young adult and adult sarcomas.  

Current active projects include:

• Treatment of molecularly-selected bone and soft tissue sarcomas with CDK4 inhibitors to synchronize and sensitize tumor cells to chemotherapy.
• Characterizing and harnessing the tumor immune microenvironment of osteosarcoma.
• Ongoing collaborations with Department of Pediatrics faculty member Dr. Monika Davare:
  • Identifying, characterizing and targeting kinase alterations in sarcomas.
  • Developing a novel small molecule therapy for Ewing sarcoma.